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296篇 您的检索式:作者名="Guoping LI"
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1Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)显示文摘In recent years,as living standards have continued to improve,the number of diabetes patients in China,along with the incidence of complications associated with the disease,has been increasing.Among these complications,diabetic foot disease is one of the main causes of disability and death in diabetic patients.Due to the differences in economy,culture,religion and level of medical care available across different regions,preventive and treatment methods and curative results for diabetic foot vary greatly.In multidisciplinary models built around diabetic foot,the timely assessment and diagnosis of wounds and appropriate methods of prevention and treatment with internal and external surgery are key to clinical practice for this pathology.In 2019,under the leadership of the Jiangsu Medical Association and Chinese Diabetes Society,the writing group for the Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)was established with the participation of scholars from the specialist areas of endocrinology,burn injury,vascular surgery,orthopedics,foot and ankle surgery and cardiology.Drawing lessons from diabetic foot guidelines from other countries,this guide analyses clinical practices for diabetic foot,queries the theoretical basis and grades and gives recommendations based on the characteristics of the pathology in China.This paper begins with assessments and diagnoses of diabetic foot,then describes treatments for diabetic foot in detail,and ends with protections for high-risk feet and the prevention of ulcers.This manuscript covers the disciplines of internal medicine,surgical,nursing and rehabilitation and describes a total of 50 recommendations that we hope will provide procedures and protocols for clinicians dealing with diabetic foot.Aiping Wang Guozhong Lv Xingbo Cheng Xianghua Ma Wei Wang Jianchao Gui JiHu Meng Lu Guoping Chu Jin’an Chen Hao Zhang Yiqiu Jiang Yuedong Chen Wengbo Yang Lin Jiang Houfa Geng Rendong Zheng Yihui Li Wei Feng Boey Johnson Wenjuan Wang Dalong Zhu Yin Hu 2020Burns & Trauma2020,8,1:34
2ZIKA virus isolated from mosquitoes:a field and laboratory investigation in China,2016显示文摘A field investigation of arboviruses was conducted in Dejiang, Guizhou Province in the summer of 2016. A total of 8,795 mosquitoes, belonging to four species of three genera, and 1,300 midges were collected. The mosquito samples were identified on site according to their morphology, and the pooled samples were ground and centrifuged in the laboratory. The supernatant was incubated with mosquito tissue culture cells(C6/36) and mammalian cells(BHK-21) for virus isolation. The results indicated that 40%(3,540/8,795) were Anopheles sinensis, 30%(2,700/8,795) were Culex pipiens quinquefasciatus, and 29%(2,530/8,795)were Armigeres subbalbeatus. Furthermore, a total of eight virus isolates were obtained, and genome sequencing revealed two Zika viruses(ZIKVs) isolated from Culex pipiens quinquefasciatus and Armigeres subbalbeatus, respectively; three Japanese encephalitis viruses(JEVs) isolated from Culex pipiens quinquefasciatus; two Banna viruses(BAVs) isolated from Culex pipiens quinquefasciatus and Anopheles sinensis, respectively; and one densovirus(DNV) isolated from Culex pipiens quinquefasciatus.The ZIKVs isolated from the Culex pipiens quinquefasciatus and Armigeres subbalbeatus mosquitoes represent the first ZIKV isolates in China's Mainland. This discovery presents new challenges for the prevention and control of ZIKV in China, and prompts international cooperation on this global issue.Shihong Fu Song Song Hong Liu Yuanyuan Li Xiaolong Li Xiaoyan Gao Ziqian Xu Guoping Liu Dingming Wang Zhenzao Tian Jingzhu Zhou Ying He Wenwen Lei Huanyu Wang Bin Wang Xiaoqing Lu Guodong Liang 2017Science China(Life Sciences)2017,60,12:25
3In vitro differentiation of adipose-derived stem cells and bone marrow-derived stromal stem cells into neuronal-like cells显示文摘Adipose-derived stem cells and bone marrow-derived stromal stem cells were co-cultured with untreated or Aβ1-40-treated PC12 cells, or grown in supernatant derived from untreated or Aβ1-40-treated PC12 cells. Analysis by western blot and quantitative real-time PCR showed that protein levels of Nanog, Oct4, and Sox2, and mRNA levels of miR/125a/3p were decreased, while expression of insulin-like growth factor-2 and neuron specific enolase was increased. In comparison, the generation of neuron specific enolase-positive cells was most successful when adipose-derived stem cells were co-cultured with Aβ1-40-treated PC12 cells. Our results demonstrate that adipose-derived stem cells and bone marrow-derived stromal stem cells exhibit trends of neuronal-like cell differentiation after co-culture with Aβ1-40-treated PC12 cells. This process may relate to a downregulation of miR-125a-3p mRNA expression and increased levels of insulin-like growth factor-2 expression.Jin Zhou Guoping Tian Jing'e Wang Xuefeng Cong Xingkai Wu Siyang Zhang Li Li Bing Xu Feng Zhu Xuedan Luo Jian Han Fengjie Hu 2011Neural Regeneration Research2011,6,19:21
4Distribution of Pacific-origin water in the region of the Chukchi Plateau in the Arctic Ocean in the summer of 2003显示文摘The upper ocean thermohaline structures in the region of the Chukchi Plateau are analyzed with the hydrographic data collected by the Chinese National Arctic Research Expedition in the summer of 2003. Three types of the Pacific-origin water were found in the upper ocean, Alaska Coastal Water (ACW), summer Bering Sea Water (sBSW) and winter Bering Sea Water (wBSW) are indicated by two maximums temperature and one minimum temperature, piling up from the upper to the lower respectively. The extreme warm ACW with a maximum temperature of 1.62 ℃ was found in the southwestern Canada Basin at a depth of about 50 m. A pathway of the ACW into the basin from its adjacent area did not existed in the expedition period. So it is speculated that the extreme warm feature of the ACW was formed locally in 2003. The relative weak ACW occurred to the east of the Chukchi Cap and in the southern Chukchi Abyssal Plain. The latter one might originate from a warm downwelling that existed in a small canyon at the shelf break of the Chukchi Sea. The sBSW without the ACW was found only at the southwestern flank of the Chukchi Cap. The ACW and the sBSW were not found in the northernmost station at 81°N,which indicates the north boundary of the upper Pacific-origin water in the Canada Basin. The wBSW, which existed in all deep stations,was exactly uniform at temperature. The difference of the core potential temperature of the wBSW in the deep regions is only 0.08 ℃.SHI Jiuxin CAO Yong ZHAO Jinping GAO Guoping JIAO Yutian LI Shujiang 2005Acta Oceanologica Sinica2005,24,6:15
5Recombinant CC16 protein inhibits the production of pro-inflammatory cytokines via NF-KB and p38 MAPK pathways in LPS-activated RAW264,7 macrophages显示文摘积累的证据显示克莱拉房间 protein-16 (CC16 ) 有反煽动性的功能,尽管深奥分子的小径完全没被阐明。这里,我们评估了效果肿瘤坏死因素 alpha (TNF-) 的表示上的 recombinant 老鼠 CC16 (rCC16 ) , interleukin-6 (IL-6 ) ,和在 lipopolysaccharide (LPS ) 的 IL-8 刺激了老鼠巨噬细胞(RAW264.7 房间) 并且探索了内在的分子的机制。rCC16 在两个禁止了导致 LPS 的 TNF- , IL-6,和 IL-8 表示,这被发现送信人 ribonucleicacid (mRNA ) 水平和蛋白质以一种集中依赖者方式铺平,由即时反向的 transcriptase 聚合酶链反应和连接酶的 immunosorbent 试金示威了。如此的镇压效果被 transcriptional 活动和原子因素(NF ) 的脱氧核糖核酸酸绑定活动的抑制伴随 -B 然而并非使活跃之物蛋白质(AP )-1。西方的污点分析进一步表明 rCC16 禁止了原子 NF-B 和 NF-B 禁止的蛋白质 IB,和 p38 的 cytosolic NF-B, phosphorylation 和减小的减小的增加激活 mitogen 的蛋白质 kinase (MAPK ) 依赖者由在它的 p65 子单元的 Ser276 的 phosphorylation 的 NF-B 激活。而且, rCC16 被发现没另外在c6月N终端 kinase ,c6月,或c-Jun.的原子 translocation 的 phosphorylation 上有效果,TNF-的减小, IL-6 ,并且 IL-8 被颠倒内长的uteroglobin有约束力的蛋白质的水平什么时候被 RNA 干扰在 对待rCC16 、 对待LPS 的 RAW264.7 房间减少。我们的数据建议 rCC16 由在 RAW264.7 房间使 NF-B 和 p38 MAPK 然而并非 AP-1 失去活性压制调停 LPS 的煽动性的调停人 TNF- , IL-6,和 IL-8 生产。Min Pang Yangyang Yuan Dong Wang Ting Li Dan Wang Xiaohong Shi Min Guo Chunfang Wang Xinri Zhang Guoping Zheng Baofeng Yu Hailong Wang 2017Acta Biochimica et Biophysica Sinica2017,49,5:14
6The bulk transfer coefficients and surface fluxes on the western Tibetan Plateau显示文摘On the gradient observational data of the atmospheric surface layer from September 1997 to December 1998 collected by two sets of Automatic Weather Station (AWS) installed in Gaize and Shiquanhe on the western Tibetan Plateau, mean surface roughness lengths at the two stations above are determined to be 2.7 and 2.9 cm, respectively. The bulk transfer coefficients each day are computed by the profile-flux method, means of the bulk transfer coefficient for momentum (i.e. drag coefficient) in 1998 are 4.83×10-3 and 4.75×103 at the two stations. The surface fluxes of momentum, sensible heat and latent heat each day are further estimated by the bulk formulas, annual mean of these fluxes is 3.4×10-2 and 1.8×102N/m2, 73.1 and 67.2 W/m2, 15.4 and 2.9 W/m2, respectively. The diurnal and seasonal variations are obtained by a composite method and the relationships among the heat transfers between land and atmosphere, plateau monsoon and plateau rain season are also discussed.Guoping Li Tingyang Duan Yuanfa Gong 2000Chinese Science Bulletin2000,45,13:13
7Inhibition of NF-κB Expression and Allergen-induced Airway Inflammation in a Mouse Allergic Asthma Model by Andrographolide显示文摘Jing Li Li Luo Xiaoyun Wang Bin Liao Guoping Li 2009Cellular & Molecular Immunology2009,6,5:11
8Effect of dry density on ^(125)I diffusion in GMZ bentonite显示文摘Gaomiaozi(GMZ) bentonite is regarded as the favorable candidate backfilling material for a potential repository in China.It is important to understand the diffusion behavior of 125 I in GMZ bentonite and compare the diffusion behavior in GMZ and other types of bentonite like MX-80,Avonlea,etc.Therefore,through-and out-diffusion experiments were conducted to obtain the effective diffusion coefficient(D e) and distribution coefficient(K d).A computer code named Fitting for diffusion coefficient(FDP) was used for the experimental data processing and theoretical modeling.At the dry density of GMZ bentonite from 1600-2000 kg/m 3,the D e values of 125 I were(2.4-20.4) × 10-12 m 2 /s and K d values were constants.At dry density above 1800 kg/m 3,the diffusion behaviors were almost the same,indicating that the anion exclusion was ineffective.Out-diffusion results showed that the species of 125 I may be changed during the diffusion processing.It was probably caused by some organic matters or reducing substances in GMZ bentonite.Since the main composition of bentonite is montmorillonite,similar diffusion parameters were obtained in GMZ and other types of bentonite.The relationship of D e and accessible porosity(acc) could be described by Archie's law with exponent n = 1.2-2.8 for 125 I diffusion in bentonite,whereas n = 2.0 in GMZ bentonite.Furthermore,bentonite with the dry density of 1800 kg/m 3 was proposed as the backfilling materials used in the construction of high level radioactivity waste repository.WU Tao LI JinYing DAI Wei XIAO GuoPing SHU FuJun YAO Jun SU YuLan SHI Lei 2012Science China Chemistry2012,55,9:11
9Induction of Th1-Type Immune Response by Chitosan Nanoparticles Containing Plasmid DNA Encoding House Dust Mite Allergen Der p2 for Oral Vaccination in Mice显示文摘This study was to prepare the chitosan-pDer p 2 nanoparticles and to investigate the effect of chitosan-DNA nanoparticles on immune response in mice by oral delivery of chitosan-DNA nanoparticles. The nanoparticles were synthesized by complexing chitosan with plasmid DNA. The DNA was fully complexed into chitosan-DNA nanoparticles,suggesting a 100% encapsulation efficiency. Chitosan-DNA complex renders a significant protection of the plasmid. No effect on cell viability was observed in both cell types and average cell viability over 100% was obtained. Oral gene delivery with chitosan-DNA nanoparticles can generate a higher level expression of gene in vivo. Oral chitosan-pDer p 2 nanoparticles in BALB/c mice can induce IFN-γ in serum and prevent subsequent sensitization of Th2 cell-regulated specific IgE responses. The data indicate that the oral administration of chitosan-pDer p 2 nanoparticles results in the expression of Der p 2 in the epithelial cells of both stomach and small intestine and the induction of Th1-type immune response.Guoping Li Zhigang Liu Bin Liao Nanshan Zhong 2009Cellular & Molecular Immunology2009,6,1:10
10Whole-Genome Resequencing of a Worldwide Collection of Rapeseed Accessions Reveals the Genetic Basis of Ecotype Divergence显示文摘Rapeseed (Brassica napus),an important oilseed crop,has adapted to diverse climate zones and latitudes by forming three main ecotype groups,namely winter,semiwinter,and spring types. However,genetic variations underlying the divergence of these ecotypes are largely unknown. Here,we report the global pattern of genetic polymorphisms in rapeseed determined by resequencing a worldwide collection of 991 germplasm accessions.A total of 5.56 and 5.53 million singlenucleotide polymorphisms (SNPs)as Well as 1.86 and 1.92 million InDels were identified by mapping reads to the reference genomes of 'Darmor-bzh'and 'Tapidor,'respectively.We generated a map of allelic drift paths that shows splits and mixtures of the main populations,and revealed an asymmetric evolution of the two subgenomes of B.napus by calculating the genetic diversity and linkage disequilibrium parameters.Selective-sweep analysis revealed genetic changes in genes orthologous to those regulating various aspects of plant development and response to stresses.A genome-wide association study identified SNPs in the promoter regions of FLOWERING LOCUS T and FLOWERING LOCUS C orthologs that corresponded to the different rapeseed ecotype groups. Our study provides important insights into the genomic footprints of rapeseed evolution and flowering-time divergence among three ecotype groups,and will facilitate screening of molecular markers for accelerating rapeseed breeding.Dezhi Wu Zhe Liang Tao Yan Ying Xu Lijie Xuan Juan Tang Gang Zhou Ulrike Lohwasser Shuijin Hua Haoyi Wang Xiaoyang Chen Qian Wang Le Zhu Antony Maodzeka Nazim Hussain Zhilan Li Xuming Li Imran Haider Shamsi Ghulam Jilani Linde Wu Hongkun Zheng Guoping Zhang Boulos Chalhoub Lisha Shen Hao Yu Lixi Jiang 2019Molecular Plant2019,12,1:10
11Therapeutic Effects of DNA Vaccine on Allergen-Induced Allergic Airway Inflammation in Mouse Model显示文摘Vaccination with DNA encoding Dermatophagoides pteronyssinus group 2 (Der p 2) allergen previously showed its effects of immunologic protection on Der p 2 allergen-induced allergic airway inflammation in mice. In present study, we investigated whether DNA vaccine encoding Der p 2 could exert therapeutic role on allergen-induced allergic airway inflammation in mouse model and explored the mechanism of DNA vaccination in asthma specific-allergen immunotherapy. After sensitized and challenged by Der p 2, the BALB/c mice were immunized with DNA vaccine. The degrees of cellular infiltration were scored. IgE levels in serum and IL-4/IL-13 levels in BALF were determined by ELISA. The lung tissues were assessed by histological examinations. Expressions of STAT6 and NF-κB in lung were determined by immunohistochemistry staining. Vaccination of mice with DNA vaccine inhibited the development of airway inflammation and the production of mucin induced by allergen, and reduced the level of Der p 2-specific IgE level. Significant reductions of eosinophil infiltration and levels of IL-4 and IL-13 in BALF were observed after vaccination. Further more, DNA vaccination inhibited STAT6 and NF-κB expression in lung tissue in Der p 2-immunized mice. These results indicated that DNA vaccine encoding Der p 2 allergen could be used for therapy of allergen-induced allergic airway inflammation in our mouse model.Guoping Li Zhigang Liu Nanshan Zhong Bin Liao Ying Xiong 2006Cellular & Molecular Immunology2006,3,5:9
12A Potential Disease Susceptibility Gene CsLOB of Citrus Is Targeted by a Major Virulence Effector PthA of Xanthomonas citri subsp, citri显示文摘Dear Editor, Citrus bacterial canker (CBC),one of the most destructive diseases of citrus,has a severe economic impact on citrus industries in tropical and subtropical countries (Das,2003).It has been widely known that Xanthomonas cirri subsp.cirri (Xcc) causes the CBC by transferring the type-Ⅲ effectors (T3SEs) to the interior of the plant cell through type-Ⅲ secretion system (T3S) to modulate transcription of host plants to trigger CBC disease (Schaad et al.,2006).Pathotype A,the Asiatic form of Xcc,has a wide host range,is pathogenic on almost all citrus varieties,and contains a major virulence gene pthA encoding a T3S-secreted transcriptional activator-like effector (TALE) that promotes cellular hypertrophy (Al-Saadi et al.,2007).However,the susceptibility gene in citrus being responsible for the CBC and matching PthA of Xcc is largely unknown.Zheng Li Lifang Zou Gang Ye Li Xiong Zhiyuan Ji Muhammad Zakria Ni Hong Guoping Wang Gongyou Chen 2014Molecular Plant2014,7,5:9
13The frequency and skewed T-cell receptor beta-chain variable patterns of peripheral CD4+CD25+ regulatory T-cells are associated with hepatitis B e antigen seroconversion of chronic hepatitis B patients during antiviral treatment显示文摘Jiezuan Yang Guoping Sheng Dangsheng Xiao Haiyan Shi Wei Wu Haifeng Lu Ping Yi Hongcui Cao Lanjuan Li 2016Cellular & Molecular Immunology2016,13,5:9
14Formation Mechanism of the Changxing Formation Gas Reservoir in the Yuanba Gas Field,Sichuan Basin,China显示文摘在很轻轻的站台边缘 paleogeographic 环境,站台边缘礁石公寓使碳酸盐水库岩石褪色在 Yuanba 的 Changxing 形成被开发地。后来弱的结构的进化和 diagenetic 进化引起了 Changxing 形成形成 lithologic 陷井,与象溶解 bioclastic dolostone 那样的好水库并且溶解了毛孔 dolostone。Changxing 形成煤气的水库是伪 layered 在压力弄空开车下面的多孔的 lithologic 气体水库,与高 H2S 和中等 CO2 内容。为 Changxing 形成煤气的水库的进行的系统可能在内在的形成在 Changxing 形成水库, Changxing 形成的最高的 erosional 表面,以及 micropores 和 microfractures 由毛孔和 microfractures 组成的这纸 predictes。Changxing 形成水库经历了控告阶段的 3 烃。这份报纸建议那散开是为这座煤气的水库的主要形成机制。在中间、迟了的 Yanshanian, Yuanba 区域进入了主要煤气的收费阶段。气体从来源岩石和另外的含有石油的阶层在小差错和 microfractures 主要通过散开并且与渗出物流动的帮助移居了到 Changxing 形成碳酸盐水库岩石,形成 lithologic 气体水池。在喜玛拉雅的时代,没有强壮的修正, lithologic 陷井总体上被高举或重叠,并且为气体是有利的保藏。LONG Shengxian HUANG Renchun LI Hongtao YOU Yuchun LIU Guoping BAI Zhenrui 2011Acta Geologica Sinica(English Edition)2011,85,1:9
15New Nodosaurid Dinosaur from the Late Cretaceous of Lishui, Zhejiang Province, China显示文摘nodosaurid 恐龙的一个新类和种:Zhejiangosaurus lishuiensisgen。et sp。nov。此处被树立。它被由至少三真骶的 vertebrae,熔化形成 presacral 杆的 5 尾的背面的 vertebrae,从身体的中间的线的肠骨的长苗条的 preacetabular 过程的宽分叉,和定位在的 fourthtrochanter 组成的骶骨描绘大腿骨中间长度。LU Junchang JIN Xingsheng SHENG Yiming LI Yihong WANG Guoping Yoichi AZUMA 2007Acta Geologica Sinica(English Edition)2007,81,3:8
16Dynamic and Numerical Study of Waves in the Tibetan Plateau Vortex显示文摘In terms of its dynamics, The Tibetan Plateau Vortex(TPV) is assumed to be a vortex in the boundary layer forced by diabatic heating and friction. In order to analyze the basic characteristics of waves in the vortex, the governing equations for the vortex were established in column coordinates with the balance of gradient wind. Based on this, the type of mixed waves and their dispersion characteristics were deduced by solving the linear model. Two numerical simulations with triple-nested domains—one idealized large-eddy simulation and one of a TPV that took place on 14 August 2006—were also carried out. The aim of the simulations was to validate the mixed wave deduced from the governing equations. The high-resolution model output data were analyzed and the results showed that the tangential flow field of the TPV in the form of center heating was cyclonic and convergent in the lower levels and anticyclonic and divergent in the upper levels. The simulations also showed that the vorticity of the vortex is uneven and might have shear flow along the radial direction. The changing vorticity causes the formation and spreading of vortex Rossby(VR) waves, and divergence will cause changes to the motion of the excitation and evolution of inertial gravity(IG) waves. Therefore, the vortex may contain what we call mixed inertial gravity–vortex Rossby(IG–VR) waves. It is suggested that some strongly developed TPVs should be studied in the future, because of their effects on weather in downstream areas.CHEN Gong LI Guoping 2014Advances in Atmospheric Sciences2014,31,1:8
17Symptom selection for multi-label data of inquiry diagnosis in traditional Chinese medicine显示文摘In traditional Chinese medicine(TCM) diagnosis,a patient may be associated with more than one syndrome tags,and its computer-aided diagnosis is a typical application in the domain of multi-label learning of high-dimensional data.It is common that a great deal of symptoms can occur in traditional Chinese medical diagnosis,which affects the modeling of diagnostic algorithm.Feature selection entails choosing the smallest feature subset of relevant symptoms,and maximizing the generalization performance of the model.At present there are rare researches on feature selection on multi-label data.A hybrid optimization technique is introduced to symptom selection for multi-label data in TCM diagnosis in this paper,and modeling is made by means of four multi-label learning algorithms like k nearest neighbors,etc.We compare the performance of the algorithm with the current popular dimension reduction algorithms like MEFS(embedded feature selection for multi-Label learning),MDDM(multi-label dimensionality reduction via dependence maximization) on the UCI Yeast gene functional data set and an inquiry diagnosis dataset of coronary heart disease(CHD).Experimental results show that the algorithm we present has significantly improved the performance.In particular,the improvement on the average precision for the classifier is up to 10.62% and 14.54%.Syndrome inquiry modeling of CHD in TCM is realized in this paper,providing effective reference for the diagnosis of CHD and analysis of other multi-label data.SHAO Huan LI GuoZheng LIU GuoPing WANG YiQin 2013Science China(Information Sciences)2013,56,5:8
18Impact of Regional Development on Carbon Emission: Empirical Evidence Across Countries显示文摘Global warming is recently an urgent issue worldwide. The increase of carbon emissions induced by human economic activities has become a major driving force behind global climate change. Thus, as a matter of social responsibility, reasonable carbon constraints should be implemented to ensure environmental security and sustainable development for every country. Based on a summary of studies that examined the relationship between carbon emissions and regional development, this paper shows that human activity-led carbon emission is caused by the combination of several influencing factors, including population size, income level, and technical progress. Thus, a quantitative model derived from IPAT-ImPACT-Kaya series and STIRPAT models was established. Empirical analysis using multivariate nonlinear regression demonstrated that the origins of growing global carbon emission included the increasing influencing elasticity of the population size and the declining negative effect of technical progress. Meanwhile, in context of classification of country groups at different income levels, according to the comparison of fluctuating patterns of the influencing elasticity, technical progress was found as the main factor influencing carbon emission levels in high-income countries, and population size might be the controlling factor in middle-income countries. However, for low-income countries, the nonlinear relationship between carbon emission and its influencing factors was not significant, whereas population growth was identified as an important potential driving force in future carbon emissions. This study can therefore provide a reference for the formulation of policies on carbon constraints, especially to develop more efficient carbon mitigating policies for countries at different income levels.LI Guoping YUAN Yuan 2014Chinese Geographical Science2014,24,5:7
19Analysis of a Vortex Precipitation Event over Southwest China Using AIRS and In Situ Measurements显示文摘A strong precipitation event caused by the southwest vortex(SWV), which affected Sichuan Province and Chongqing municipality in Southwest China on 10–14 July 2012, is investigated. The SWV is examined using satellite observations from AIRS(Atmospheric Infrared Sounder), in situ measurements from the SWV intensive observation campaign, and MICAPS(Marine Interactive Computer-Aided Provisioning System) data. Analysis of this precipitation process revealed that:(1)heavy rain occurred during the development phase, and cloud water content increased significantly after the dissipation of the SWV;(2) the area with low outgoing longwave radiation values from AIRS correlated well with the SWV;(3) variation of the temperature of brightness blackbody(TBB) from AIRS reflected the evolution of the SWV, and the values of TBB reduced significantly during the SWV's development; and(4) strong temperature and water vapor inversions were noted during the development of the SWV. The moisture profile displayed large vertical variation during the SWV's puissant phase,with the moisture inversion occurring at low levels. The moisture content during the receding phase was significantly reduced compared with that during the developing and puissant phases. The vertical flux of vapor divergence explained the variation of the moisture profile. These results also indicate the potential for using AIRS products in studying severe weather over the Tibetan Plateau and its surroundings, where in situ measurements are sparse.Chengcheng NI Guoping LI Xiaozhen XIONG 2017Advances in Atmospheric Sciences2017,34,4:7
20MicroRNAs in heart and circulation during physical exercise显示文摘Exercise training is beneficial to the cardiovascular system. MicroRNAs(miRNAs, miRs) are a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of eukaryotic gene expression. Exercise training alters the expression levels of large amounts of miRNAs in the heart. In addition, circulating miRNAs appear to be regulated by exercise training. In this review, we will summarize recent advances in the regulation of miRNAs during physical exercise intervention in various cardiovascular diseases, including pathologic cardiac hypertrophy, myocardial fibrosis, ischemia-reperfusion injury, myocardial infarction, and heart failure. The regulatory role of circulating miRNAs after exercise training was also reviewed. In conclusion, miRNAs might be a valuable target for treatment of cardiovascular diseases and have great potential as biomarkers for assessment of physical performance.Lijun Wang Yicheng Lv Guoping Li Junjie Xiao 2018Journal of Sport and Health Science2018,7,4:7
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