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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Diagnostic value of negative enrichment and immune fluorescence in situ hybridization for intraperitoneal free cancer cells of gastric cancer显示文摘Objective:To explore the intraperitoneal free cancer cell(IFCC)detection value of negative enrichment and immune fluorescence in situ hybridization(NEimFISH)on chromosomes(CEN)8/17.Methods:To verify the reliability of NEimFISH,29 gastric cancer tumors,their adjacent tissues and greater omental tissues were tested.Our study then included 105 gastric cancer patients for IFCC.We defined patients as IFCC-positive if a signal was detected,regardless of the detailed cancer cell numbers.A comparison of clinicopathological features was conducted among IFCC groups.We also compared the diagnosis value and peritoneal recurrence predictive value among different detection methods.The comparison of IFCC number was also conducted among different groups.Results:A cutoff of 2.5 positive cells could distinguish all benign tissue samples and 97%of malignant tissue samples in our study.Compared to intestinal gastric cancer,patients with diffuse gastric cancer tended to have more IFCCs(6 vs.4,P=0.002).The IFCC counts were often higher in the lymphovascular invasion positive group than negative group(3 vs.1,P=0.022).All IFCC samples that were considered positive using conventional cytology were also found to be positive using NEimFISH.When compared to conventional cytology and paraffin pathology,NEimFISH had a higher IFCC positive rate(68.9%)and higher one-year peritoneal recurrence predictive value with area under the curve(AUC)of 0.922.Conclusions:Gastric cancer could be effectively diagnosed by NEimFISH.The IFCC number found using NEimFISH on CEN8/17 is closely associated with Lauren type and vascular invasion of cancer.NEimFISH is a reliable detection modality with a higher positive detection rate,higher one-year peritoneal recurrence predictive value and quantitative features for IFCC of gastric cancer. | Anqiang Wang Zhongwu Li Qian Wang Yali Bai Xin Ji Tao Fu Ke Ji Yanwen Xue Tingxu Han Xiaojiang Wu Ji Zhang Yingjie Yang Guobin Xu Zhaode Bu Jiafu Ji | 2019 | Chinese Journal of Cancer Research2019，31，6： | 3 |
| 3 | 显示文摘 | Zhang Guobin Shi Chaoshu Han Zhengfu | 2001 | Chin Phys Lett2001，19，3： | 1 |
| 4 | 2017年中国出现的H7N9高致病性病毒的快速进化显示文摘文章简介为了防控H7N9病毒,中国2017年9月开始对鸡进行了H5/H7二价禽流感灭活疫苗。为了解H7N9病毒在中国家禽中的分布情况,研究团队进行了系统的禽流感病毒监测。2017年2月至2017年5月之间在379个活禽市场和665个家禽养殖场共采集30201份样品(其中活禽市场采集12504份. | Jianzhong Shi Guohua Deng Shujie Ma Xianying Zeng Xin Yin Mei Li Bo Zhang Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Liling Liu Pucheng Chen Yongping Jiang Yuntao Guan Jinxiong Liu Wenli Gu Shuyu Han Yangming Song Libin Liang Zhiyuan Qu Yujie Hou Xiurong Wang Hongmei Bao Guobin Tian Yanbing Li Li Jiang Chengjun Li 陈化兰 | 2019 | 科学新闻2019，0，2： | 1 |
| 5 | Exponential isothermal amplification coupled MALDI-TOF MS for microRNAs detection显示文摘Micro RNAs(mi RNAs) have attracted significant attention in biomedical research and clinical diagnosis.However, due to their inherent characteristics of low abundance and the high complexity of corresponding biological matrices, simultaneous detection of multiple mi RNAs at low abundance is still a challenge.In this work, a method coupling exponential amplification reaction(EXPAR) with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS) is developed for label-free and simultaneous detection of multiple mi RNAs. The assay can be performed under isothermal conditions in a single reaction tube, and finished in less than 30 min. It exhibits good quantification ability and with attomolar-level sensitivity for mi RNAs detection. It also shows high specificity to distinguish mi RNAs at single-nucleotide resolution. We used the method to detect the mi RNA-21, let-7a, mi RNA-100, and mi RNA-125b in samples of spiked human serum and breast cancer cells(i.e., MCF-7, MDA-MB-231 and SK-BR-3). The quantification results were well consistent with the standard real-time fluorescence EXPAR.Consequently, the label-free mass-spectrometric platform could be a potential tool for mi RNAs analysis in complex biological samples, and may be used for clinical diagnosis. | Guobin Han Dandan Li Qiuyuan Lin Jia Yi Qian Lyu Qingwei Ma Liang Qiao | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
| 6 | Distortion minimization for multimedia transmission in NOMA HAP-UAV integrated aerial access networks显示文摘Aerial access networks have been envisioned as a promising 6G solution to enhance the ground communication systems in both coverage and capacity. To better utilize the spectrum and fully explore different channel characteristics, this paper constructs an integrated network comprising the High Altitude Platform(HAP) and Unmanned Air Vehicles(UAVs) with the NonOrthogonal Multiple Access(NOMA) technology. In order to improve the transmission quality of images and videos, a power management scheme is proposed to minimize the distortion of the transmissions from the HAP and UAVs to the terminals. The power control is formulated as a non-convex problem constrained by the maximal transmit power and the minimal terminal rate requirements. The variable substitution and the first-order Tailor’s expansion is used to transform it into a sequence of convex problems, which are subsequently solved through the gradient projection method. Simulation demonstrates the signal distortion and error rate improvement achieved by the proposed algorithm. | Guobin ZHANG Zhu HAN Hang XIN Xin WEI Boya DI | 2022 | Chinese Journal of Aeronautics2022，35，9： | 0 |
| 7 | Droplets deposition and harvest-aid efficacy for UAV application in arid cotton areas in Xinjiang,China显示文摘With the development of Unmanned Aerial Vehicle(UAV)sprayers,the application of low-volume spraying of harvest-aid and other agrochemicals to cotton using UAVs is becoming a new agronomic trend worldwide.The effect of spray volume and canopy density for UAV spraying is significant but was rarely studied.In this study,five representative spray volumes were explored to examine the effect of spray volume on deposition and harvest-aid efficacy for cotton using a UAV sprayer.To explore the effect of canopy density,similar tests were carried out in a field located nearby with a lower leaf area index(LAI).A conventional trailer boom sprayer was selected for comparison.Different spray volumes had a significant effect on defoliation,but had no significant effect on boll opening and fiber quality.A higher defoliation rate was achieved in the lower LAI field.The total rate of defoliation using the UAV was inferior to the boom sprayer in the high LAI field for lower deposition and defoliation rate in the lower canopy.Considering the deposition,defoliation rate,and working efficiency,a spray volume of 15.0 L/hm^(2) with an average droplet size of 150μm is recommended for UAV application. | Guobin Wang Jiahui Wang Pengchao Chen Xiaoqiang Han Shengde Chen Yubin Lan | 2022 | International Journal of Agricultural and Biological Engineering2022，15，5： | 0 |
| 8 | Regulating the Electronic Structure of Fe^(3+)‑Doped BiOCl_(x)I_(1-x)Solid Solution by an Amidoxime‑Functionalized Fibrous Support for Efficient Photocatalysis显示文摘BiOX(X=Cl,I,Br)has attracted intensive interest as a photocatalyst for environmental remediation,but its limited pho-tocatalytic activity versus visible light irradiation restricts its practical application.Herein,a Fe^(3+)-doped BiOCl_(x)I_(1-x)solid solution(Fe-BiOCl_(x)I_(1-x))was synthesized in situ on an amidoxime-functionalized fibrous support via a one-pot solvothermal approach.Comprehensive characterization and DFT calculations indicate that the robust chelated interaction between ami-doxime groups and Fe^(3+)greatly boosts the crystal growth of nanosized Fe-BiOCl_(x)I_(1–x)on the fibrous surface,simultaneously tunes its electronic structure for improved light harvesting and oxygen vacancy creation,and enables the fibrous support to act as an electron sink for efficient charge separation.These synergistic qualities result in high photocatalytic activity for the degradation of organic contaminants,which outperforms that obtained for unsupported Fe-BiOCl_(x)I_(1-x)and other fibrous samples by several times.Our findings highlight the importance of functionalized support design for the development of efficient BiOX photocatalysts under visible light irradiation. | Zhenbang Han Mingze Lv Xianbing Shi Guobin Li Jin Zhao Xiaoming Zhao | 2023 | Advanced Fiber Materials2023，5，1： | 0 |
| 9 | Microglial NLRP3 inflammasome-mediated neuroinflammation and therapeutic strategies in depression显示文摘Previous studies have demonstrated a bidirectional relationship between inflammation and depression.Activation of the nucleotide-binding oligomerization domain,leucine-rich repeat,and NLR family pyrin domain-containing 3(NLRP3)inflammasomes is closely related to the pathogenesis of various neurological diseases.In patients with major depressive disorder,NLRP3 inflammasome levels are significantly elevated.Understanding the role that NLRP3 inflammasome-mediated neuroinflammation plays in the pathogenesis of depression may be beneficial for future therapeutic strategies.In this review,we aimed to elucidate the mechanisms that lead to the activation of the NLRP3 inflammasome in depression as well as to provide insight into therapeutic strategies that target the NLRP3 inflammasome.Moreover,we outlined various therapeutic strategies that target the NLRP3 inflammasome,including NLRP3 inflammatory pathway inhibitors,natural compounds,and other therapeutic compounds that have been shown to be effective in treating depression.Additionally,we summarized the application of NLRP3 inflammasome inhibitors in clinical trials related to depression.Currently,there is a scarcity of clinical trials dedicated to investigating the applications of NLRP3 inflammasome inhibitors in depression treatment.The modulation of NLRP3 inflammasomes in microglia holds promise for the management of depression.Further investigations are necessary to ascertain the efficacy and safety of these therapeutic approaches as potential novel antidepressant treatments. | Qiuqin Han Wenhui Li Peiqing Chen Lijuan Wang Xiwen Bao Renyan Huang Guobin Liu Xiaorong Chen | 2024 | Neural Regeneration Research2024，19，9： | 0 |
| 10 | Preface显示文摘As the chairs of the 8th International Conference of Pioneer Computer Scientists,Engineers and Educators 2022(ICPCSEE 2022,originally ICYCSEE),it is our great pleasure to welcome you to the conference proceedings.ICPCSEE 2022 was held in Chengdu,China,during August 19-22,2022,and hosted by the Southwest Petroleum University,the University of Electronic Science and Technology of China,and the National Academy of Guo Ding Institute of Data Sciences,China. | Liehui Zhang Hongzhi Wang Yang Wang Guobin Zhu Qilong Han | 2022 | 国际计算机前沿大会会议论文集2022，，2： | 0 |
| 11 | Chronology and Geochemistry of the Berezitovoe Polymetallic Gold Deposit in Eastern Siberia, Russia and its Geological Significance显示文摘The Berezitovoe deposit is a large-sized Au-Ag-Zn-Pb deposit in the east of the SelengaStanovoi superterrane, Russia. Au-Ag orebodies are hosted by tourmaline-garnet-quartz-muscovite metasomatic rocks; Zn-Pb orebodies are hosted by granodiorites, porphyritic granites and tourmalinegarnet-quartz-muscovite metasomatic rocks. These orebodies are surrounded by wall rocks dominated by the Tukuringra Complex granodiorites, porphyritic granites, and gneissic granodiorites. The alteration includes silicification and garnet, sericitization chloritization, carbonatization and kaollinization. LA-ICP-MS U-Pb zircon dating indicates that the gold mineralization can be divided into two stages in the Berezitovoe polymetallic gold deposit(at 363.5 ± 1.5 Ma, and133.4± 0.5).Hornblende-plagioclase gneisses of the Mogocha Group in the study area underwent Paleoproterozoic metamorphism(at 1870 ± 7.8 and 2400 ± 13 Ma), gneissic granodiorite of the Tukuringra Complex yields a late Paleozoic magmatic age(at 379.2 ± 1.1 Ma),and subalkaline porphyritic granitoid of the Amudzhikan Complex yield late Mesozoic magmatic ages(133-139 and 150-163 Ma). Granodiorites of the Tukuringra Complex in the study area have high concentrations of SiO_2(average of 60.9 wt%), are aluminum-oversaturated(average A/CNK of 1.49), are enriched in the large ion lithophile elements(e.g.,K, Rb, and Ba), U, Th, and Pb, are depleted in high field strength elements(e.g., Ta, Nb, and Ti), and have slightly negative Eu and no Ce anomalies in chondrite-normalized rare earth element diagrams.Fluid inclusions from quartz veins include three types: aqueous two-phase, CO_2-bearing three-phase,and pure CO_2. Aqueous two-phase inclusions homogenize at 167℃-249℃ and have salinities of 4.32%-9.47% NaCl equivalent, densities of 0.86-0.95 g/cm^3, and formed at depths of 0.52-0.94 km. In comparison, the C0_2-bearing three-phase inclusions have homogenization temperatures of 265℃-346℃,salinities of 7.14%-11.57% NaCl equivalent, and total densities of 0.62-0.67 g/cm^3. The geochemical and zircon U-Pb data and the regional tectonic evolution of the study area, show that the Berezitovoe polymetallic gold deposit formed in an island arc or active continental margin setting, most probably related to late Paleozoic subduction of Okhotsk Ocean crust beneath the Siberian Plate. | ZHANG Guobin YANG Yanchen Alexander S.VAKH Vadim G. KHOMICH WANG Keyong YE Songqing HAN Shijiong | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 0 |
| 12 | Preface显示文摘As the chairs of the 8th International Conference of Pioneer Computer Scientists,Engineers and Educators 2022(ICPCSEE 2022,originally ICYCSEE),it is our great pleasure to welcome you to the conference proceedings.ICPCSEE 2022 was held in Chengdu,China,during August 19–22,2022,and hosted by the Southwest Petroleum University,the University of Electronic Science and Technology of China,and the National Academy of Guo Ding Institute of Data Sciences,China. | Liehui Zhang Hongzhi Wang Yang Wang Guobin Zhu Qilong Han | 2022 | 国际计算机前沿大会会议论文集2022，，1： | 0 |
| 13 | Plug Seedling Production of Short Vine Type Sweet Potato Variety‘Ganshu No.2’显示文摘This study was conducted to investigate the effects of different vine cuttings and provide a fast method for production of high-quality sweet potato seedlings.With short vine type‘Ganshu No.2'as an experiment material,biological characteristics of sweet potato seedlings were investigated by setting three vine sections( the ingle-node section,dual-node section and three-node top bud section) using three kinds of substrates( red soil,leaf mould and pond sludge).The results showed that the dual-node vine section plus leaf mould treatment sprouted earliest( 3 d) with the highest survival rate( 86.6%),root number( 9.2 roots) and the longest root length( 5.9 cm),compared with other treatments.Therefore,dual-node vine section plus leaf mould plug seedling raising has the characteristics of short sprouting time,high survival rate and low cost.The method could provide seedlings in a short period( 20 d),improves sweet potato propagation coefficient and is worth extending and applying. | Xiaosan LIU Guobin XIAO Yazhen LI Fuliang XIAO Han LI Xiaojun XIAO Tianbao HUANG | 2018 | Agricultural Biotechnology2018，7，6： | 0 |
| 14 | Proton storage chemistry in aqueous zinc-organic batteries:A review显示文摘Benefiting from the advantageous features of structural diversity and resource renewability,organic electroactive compounds are considered as attractive cathode materials for aqueous Zn-ion batteries(ZIBs).In this review,we discuss the recent developments of organic electrode materials for aqueous ZIBs.Although the proton(H^(+))storage chemistry in aqueous Zn-organic batteries has triggered an overwhelming literature surge in recent years,this topic remains controversial.Therefore,our review focuses on this significant issue and summarizes the reported electrochemical mechanisms,including pure Zn^(2+)intercalation,pure H^(+)storage,and H^(+)/Zn^(2+)co-storage.Moreover,the impact of H^(+)storage on the electrochemical performance of aqueous ZIBs is discussed systematically.Given the significance of H^(+)storage,we also highlight the relevant characterization methods employed.Finally,perspectives and directions on further understanding the charge storage mechanisms of organic materials are outlined.We hope that this review will stimulate more attention on the H^(+)storage chemistry of organic electrode materials to advance our understanding and further its application. | Xianming Deng James Kumankuma Sarpong Guobin Zhang Jing Hao Xu Zhao Linyuan Li Hongfei Li Cuiping Han Baohua Li | 2023 | InfoMat2023，5，2： | 0 |
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