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578篇 您的检索式:作者名="Guida"
    题名 作者 年代 出处 被引量
1Preparation of Unsupported Molybdenum Phosphide Hydrofining Catalysts显示文摘LI Fengyan, ZHAO Tianbo, SUN Guida, LI Cuiqing (Department of Applied Chemistry, Beijing Institute of Petrochemical Technology, Beijing 102617, China) 2003催化学报2003,24,2:10
2Lymphocyte subsets predictive value and possible involvement of human papilloma virus infection on breast cancer molecular subtypes显示文摘AIM To detect human papilloma virus(HPV) presence and to characterize cellular immune response in breast cancer patients. METHODS A total of 74 women were included, of which 48 samples were from patients diagnosed with breast cancer and 26 patients with benign pathology of the breast. Molecular subtype classification was performed based on the immunohistochemical reports of the tumor piece. HPV genome detection and genotyping from fresh breast biopsies was performed using the INNO-LIPA HPV Genotyping Extra test(Innogenetics, Ghent, Belgium). CD3+, CD4+, CD8+ and natural killer(NK)+ cells levels from peripheral blood samples from patients with breast cancer and benign pathology were measured by flow cytometry. RESULTS Luminal A was the most frequent breast cancer molecular subtype(33.33%). HPV was detected in 25% of the breast cancer patients, and genotype 18 was the most frequent in the studied population. The mean of CD3+, CD4+ and CD8+ subpopulations were decreased in patients with breast cancer, in relation to those with benign pathology, with a statistically significant difference in CD8+ values(P = 0.048). The mean of NK+ cells was increased in the benign pathology group. The average level of CD3+, CD4+, CD8+ and NK+ cells decreased as the disease progressed. HER2+ and Luminal B HER2+ tumors had the lowest counts of cell subsets. HPV breast cancer patients had elevated counts of cellular subsets. CONCLUSION Determining level changes in cellular subsets in breast cancer patients is a useful tool to evaluate treatment response.Andreína Fernandes Adriana Pesci-Feltri Isabel García-Fleury Marco López Vincent Guida Marisol De Macedo María Correnti 2018World Journal of Clinical Oncology2018,9,7:5
3Chlorinated paraffins in the technosphere:A review of available information and data gaps demonstrating the need to support the Stockholm Convention implementation显示文摘Chlorinated paraffins(CPs)have been produced for a wide range of applications,mostly in open uses,such as metalworking fluids,lubricants,coolants or additives in consumer goods.The production volume is more than one million tonnes requiring control of the lifecycle of these persistent and bioaccumulative chemicals.In May 2017,the Stockholm Convention amended its Annex A to list short chain chlorinated paraffins(SCCPs)as a Persistent Organic Pollutant(POP).Additionally,a limit for the presence of SCCPs in other CP mixtures was set at 1%by weight.CPs can be released to the environment throughout their lifecycle.Therefore,the major objective of this review was to assess and compile information on SCCPs and other CPs regarding their lifecycle in the technosphere to support the Stockholm Convention implementation.A few studies have assessed CP production plants and contamination in the surrounding environments.However,there was no systematic investigation of release routes from production and no assessment of associated landfills,even though these are known major pollution sources at other organochlorine production sites.Some studies have reported that industrial areas,where CPs have likely been used,have elevated levels of CPs in sediments and soil.However,although CPs are largely released when used as metalworking fluids or lubricants,no systematic assessment of releases has been conducted at the thousands of sites where CPs are used in high volumes.Many CPs,mainly medium chain chlorinated paraffins(MCCPs)and SCCPs,are used as additives in the production of consumer goods,resulting in exposure risks.Levels above the European Union regulation for SCCPs of 1500 mg kg^-1 and up to approx.20%are frequently found.The end-of-life management of CP-containing products is difficult since no labelling requirement exists even for products containing SCCPs.The Stockholm Convention prohibits the recycling of SCCP-containing products,which will result in challenges recycling the impacted waste categories.The activities under the Stockholm Convention related to SCCPs,such as the inventory,phase-out,and management of impacted products,provide opportunities to address existing data gaps and challenges.Special attention needs to be given to developing countries with lacking analytical capacity as well as waste management and destruction capacity.Yago Guida Raquel Capella Roland Weber 2020Emerging Contaminants2020,6,1:4
4Physicochemical Properties and Catalytic Performance of a Novel Aluminosilicate Composite Zeolite for Hydrocarbon Cracking Reaction显示文摘A novel micro-micro/mesoporous aluminosilicate ZSM-5-Y/MCM-41 composite molecular sieve with a MCM-41 type structure was synthesized through a novel process of the self-assembly of CTAB surfactant micellae with silica-alumina source originated from alkaline treatment of ZSM-5 zeolite.The physical properties of the ZSM-5- Y/MCM-41 composite molecular sieve were characterized by XRD,Py-FTIR and N_2 adsorption-desorption techniques. Different kinds of molecular sieves including ZSM-5,Y zeolite,Al-MCM-41,ZSM-5/MCM-41 and ZSM-5-Y/MCM- 41 as cracking catalysts were investigated,using 1,3,5-triisopropylbenzene(1,3,5-TIPB) as the probe molecule.Catalytic tests showed that the ZSM-5-Y/MCM-41 composite molecular sieve exhibited higher catalytic activity compared with the microporous ZSM-5 zeolite,Y zeolite,mesoporous Al-MCM-41 molecular sieve and ZSM-5/MCM-41 composite molecular sieve under the same conditions.The remarkable catalytic activity was mainly attributed to the presence of the hierarchical pore structure and proper acidity in the ZSM-5-Y/MCM-41 composite catalyst.Meanwhile, a carbenium ion mechanism was put forward for the cracking of 1,3,5-TIPB.Qi Jian Zhao Tianbo Xu Xin Li Fengyan Sun Guida 2010China Petroleum Processing & Petrochemical Technology2010,12,1:4
5Complete mesocolic excision and central vascular ligation in colorectal cancer in the era of minimally invasive surgery显示文摘Since the 19th century,appropriate lymphadenectomy has been considered a cornerstone of oncologic surgery and one of the most important prognostic factors.This approach can be applied to any surgery for gastrointestinal cancer.During surgery for colon and rectal cancer,an adequate portion of the mesentery is removed together with the segment of bowel affected by the disease.The adequate number of lymph nodes to be removed is standardized and reported by several guidelines.It is mandatory to determine the appropriate extent of lymphadenectomy and to balance its oncological benefits with the increased morbidity associated with its execution in cancer patients.Our review focuses on the concept of“complete mesenteric excision(CME)with central vascular ligation(CVL),”a radical lymphadenectomy for colorectal cancer that has gained increasing interest in recent years.The aim of this study was to evaluate the evolution of this approach over the years,its potential oncologic benefits and potential risks,and the improvements offered by laparoscopic techniques.Theoretical advantages of CME are improved local-relapse rates due to complete removal of the intact mesocolic fascia and improved distance recurrence rates due to ligation of vessels at their origin(CVL)which guarantees removal of a larger number of lymph nodes.The development and worldwide diffusion of laparoscopic techniques minimized postoperative trauma in oncologic surgery,providing the same oncologic results as open surgery.This has been widely applied to colorectal cancer surgery;however,CME entails a technical complexity that can limit its wide minimally-invasive application. This review analyzesresults of these procedures in terms of oncological outcomes, technical feasibilityand complexity, especially within the context of minimally invasive surgery.Marzia Franceschilli Sara Di Carlo Danilo Vinci Bruno Sensi Leandro Siragusa Vittoria Bellato Roberto Caronna Piero Rossi Giuseppe Cavallaro Andrea Guida Simone Sibio 2021World Journal of Clinical Cases2021,9,25:2
6Early diverting colostomy for perianal sepsis in children with acute leukemia显示文摘Alessio Pini Prato Elio Castagnola Concetta Micalizzi Carlo Dufour Stefano Avanzini Luca Pio Edoardo Guida Girolamo Mattioli Vincenzo Jasonni Nicola Disma Leila Mameli Giovanni Montobbio Piero Buffa 2012Journal of Pediatric Surgery2012,,10:2
7Myocardial protection during aortic surgery:comparison between Bretschneider-HTK and cold blood cardioplegia显示文摘Scrascia G Guida P Rotunno C 0,,05:2
8智能情报检索的用户模拟显示文摘本文介绍了IR-NLIⅡ系统—一个能使临时用户使用联机情报检索系统和包含用户模拟能力的专家接口。它是通过为具体应用领域所推荐的用户模型的组织及系统运行中作用的描述,阐释了一个用户模拟于系统。同时,还描述了建立这种模型所使用的技术.这些都以描述一类典型用户的模框(Stereotype)为基础的.Giorgio Brajnik Giovanni Guida Carlo Tasso 贾同兴 1990现代图书情报技术1990,,4:2
9Prognostic role of sub- clinical hypothyroidism in chronic heart failure outpatients显示文摘IACOVIELLO M GUIDA P GUASTAMACCHIA E et ol 2008Curr Pharm Des2008,14,26:1
10Nasal nitric oxide concentration in suspected chronic rhinosinusitis显示文摘Bommarito L Guida G Hef tier E 2008Ann Allergy Asthma Immunol2008,101,4:1
11The role of macrophages polarization in predicting prognosis of radically re- sected gastric cancerpatients显示文摘PANTANO F BERTI P GUIDA FM 2013J Cell Mol Med2013,17,11:1
12Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor显示文摘Wu Y Sun H Basta-Pljakic J Cardoso L Kennedy OD Jasper H Domene H Karabatas L Guida C Schaffler MB Rosen CJ Yakar S 0,,:1
13Development of knowledge about osteoporosis in the world of orthopedics and traumatology显示文摘Guida G lolascon G Gimigliano F 2011Aging clinical and experimental research2011,23,2:1
14Perforated appendix with abscess: hnmediate or interval appendectomy? Some examples to explain our choice 显示文摘Guida E Pederiva F Grazia MD 2015Int J Surg Case Rep2015,12,:1
15Laparoscopic or open hemicolectomy for elderly patients with right colon cancer A retrospective analysis显示文摘Guida F Clemente M Valvano L 2015G Chir2015,36,5:1
16Characterization of multipotent cells from human adult hair follicles显示文摘Raposio E Guida C Baldeni I 2007Toxicol In Vitro2007,21,2:1
17Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis显示文摘MAGNONE M BRUZZONE S GUIDA L 2009J Biol Chem2009,284,17:1
18The chicken Il-I receptor:differential evolution of the cytoplasmic and extracellular domains显示文摘GUIDA S HEGUY A MELLI M 1992Gene1992,111,:1
19UbcHl0 expression may be a useful tool in the prognosis of ovarian carcinomas显示文摘Berlingieri MT Pallante P Guida M 2007Oncogene2007,26,14:1
20Selective chemical probe inhibitor of STATI, identified through structure-based virtual screening, induces antitumor activity显示文摘Siddiquee K Zhang S Guida WC 2007Proc Natl Acad Sci USA2007,104,18:1
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