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| 1 | 内脏脂肪组织通过产生骨桥蛋白调控成纤维细胞衰老促进心脏衰老显示文摘老化通过增加包括骨桥蛋白(osteopontin,OPN)在内的细胞外基质(extracellular matrix,ECM)蛋白的沉积引起心脏结构和功能改变进而导致进行性间质纤维化。虽然已知OPN参与各种病理状况,但其在心肌衰老中的作用仍不清楚。 | Sawaki D Czibik G Pini M Ternacle J Suffee N Mercedes R Marcelin G Surenaud M Marcos E Gual P Clément K Hue S Adnot S Hatem SN Tsuchimochi I Yoshimitsu T Hénégar C Derumeaux G 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，3： | 14 |
| 2 | Targeting PVR(CD155)and its receptors in anti-tumor therapy显示文摘Poliovirus receptor(PVR,CD155)has recently been gaining scientific interest as a therapeutic target in the field of tumor immunology due to its prominent endogenous and immune functions.In contrast to healthy tissues,PVR is expressed at high levels in several human malignancies and seems to have protumorigenic and therapeutically attractive properties that are currently being investigated in the field of recombinant oncolytic virotherapy.More intriguingly,PVR participates in a considerable number of immunoregulatory functions through its interactions with activating and inhibitory immune cell receptors.These functions are often modified in the tumor microenvironment,contributing to tumor immunosuppression.Indeed,increasing evidence supports the rationale for developing strategies targeting these interactions,either in terms of checkpoint therapy(i.e.,targeting inhibitory receptors)or in adoptive cell therapy,which targets PVR as a tumor marker. | Paola Kučan Brlić Tihana Lenac Roviš Guy Cinamon Pini Tsukerman Ofer Mandelboim Stipan Jonjić | 2019 | Cellular & Molecular Immunology2019，16，1： | 10 |
| 3 | Enamel microabrasion: An overview of clinical and scientific considerations显示文摘Superficial stains and irregularities of the enamelare generally what prompt patients to seek dental intervention to improve their smile. These stains or defects may be due to hypoplasia, amelogenesis imperfecta, mineralized white spots, or fluorosis, for which enamel microabrasion is primarily indicated. Enamel microabrasion involves the use of acidic and abrasive agents, such as with 37% phosphoric acid and pumice or 6% hydrochloric acid and silica, applied to the altered enamel surface with mechanical pressure from a rubber cup coupled to a rotatory mandrel of a lowrotation micromotor. If necessary, this treatment can be safely combined with bleaching for better esthetic results. Recent studies show that microabrasion is a conservative treatment when the enamel wear is minimal and clinically imperceptible. The most important factor contributing to the success of enamel microabrasion is the depth of the defect, as deeper, opaque stains, such as those resulting from hypoplasia, cannot be resolved with microabrasion, and require a restorative approach. Surface enamel alterations that result from microabrasion, such as roughness and microhardness, are easily restored by saliva. Clinical studies support the efficacy and longevity of this safe and minimally invasive treatment. The present article presents the clinical and scientific aspects concerning the microabrasion technique, and discusses the indications for and effects of the treatment, including recent works describing microscopic and clinical evaluations. | Núbia Inocencya Pavesi Pini Daniel Sundfeld-Neto Flavio Henrique Baggio Aguiar Renato Herman Sundfeld Luis Roberto Marcondes Martins José Roberto Lovadino Débora Alves Nunes Leite Lima | 2015 | World Journal of Clinical Cases2015，3，1： | 6 |
| 4 | Early diverting colostomy for perianal sepsis in children with acute leukemia显示文摘 | Alessio Pini Prato Elio Castagnola Concetta Micalizzi Carlo Dufour Stefano Avanzini Luca Pio Edoardo Guida Girolamo Mattioli Vincenzo Jasonni Nicola Disma Leila Mameli Giovanni Montobbio Piero Buffa | 2012 | Journal of Pediatric Surgery2012，，10： | 2 |
| 5 | Sorption and swelling of poly(D,L-lactic acid)and poly(lactic-co-glycolic acid)in supercritical CO2:An experimental and modeling Study显示文摘 | R Pini G Storti M Mazzotti | 2008 | Polymer Science Part B:Polymer Physics2008，46，5： | 1 |
| 6 | Diagnosis of Bacteriuria and Leukocyturia by Automated Flow Cytometry Compared with Urine Culture显示文摘 | Pieretti B Brunat P Pini B | 2010 | Journal Of Clinical Microbiology2010，48，： | 1 |
| 7 | Factors affecting the healing response of the intrabony defects following guided tissue regeneration and access flap surgery 显示文摘 | Tonetti MS Pini Prato G Cortellini P | 1996 | J Clin Periodon- tol1996，23，： | 1 |
| 8 | Induction of c-fos-like protein in spinal cord neurons following sensory stimulation显示文摘 | Hunt SP Pini A Evan G | | 0，，6131： | 1 |
| 9 | Two years of a fungal aerobioeontamination survey in a Florentine haematology ward显示文摘 | Pini G Donato R Faggi E | 2004 | Eur J Epidemiol2004，19，7： | 1 |
| 10 | Periodontal regeneration of human intrabony defects with titanium reinforced membranes显示文摘 | Cortellini P Pini Prato G Tonetti MS | 1995 | Periodontol1995，66，9： | 1 |
| 11 | First example of a silica gel-supported optically active Mn( Ⅲ)-Salen complex as a heterogeneous asymmetric catalyst in the epoxidation of ole fins显示文摘 | PINI D MANDOLI A ORLANDI S | 1999 | Tetrahedron: Asymmetry1999，10，20： | 1 |
| 12 | Invexity and generalized convexity 显示文摘 | Pini R | 1991 | Optimization1991，22，： | 1 |
| 13 | APilot Study of Pro-urokinase in the Treatment of Deep Vein Thrombosis显示文摘 | Moia M Mannucci P M Pini M | 1994 | Thrombosis and Haemostasis1994，72，3： | 1 |
| 14 | Identification of carotid 'vulnera-ble plaque' by contrast-enhanced ultrasonography: correlation with plaque histology, symptoms and cerebral computed tomography 显示文摘 | Faggioli GL Pini R Mauro R | 2011 | Eur J Vasc Endovasc Surg2011，41，2： | 1 |
| 15 | Multiobjective Programming under Generalized Type I Invexity 显示文摘 | Hanson M A Pini R Singh C | 2001 | Journal of Mathematical Analysis and Applications2001，281，2： | 1 |
| 16 | Enzyme - Linked Immunosorbent Assay (ELISA) in the Serodiagnosis of Hydatid Disease 显示文摘 | IACONA A PINI C VICARI G | 1986 | American Journal of Tropical Medicine and Hygiene1986，35，： | 1 |
| 17 | Invexity and generalized convexity 显示文摘 | Pini R | 1991 | Optimization1991，22，： | 1 |
| 18 | Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instability 显示文摘 | Cipollone F Prontera C Pini B | 2001 | Circulation2001，104，8： | 1 |
| 19 | Laparoscopic simultaneous treatment of peripelvic renal cysts and stones: caseseries显示文摘 | Mieali S Pini G Sighinolfi MC | 2009 | J En- dourol2009，23，11： | 1 |
| 20 | Elevated circulating level of monocyte chemoattractantPretein-1 in the patients with restenosis after coronary angioplasty显示文摘 | Cipollune F Marini M Pini B | 2001 | Arterioscler Thromb Vasc Biol2001，21，3： | 1 |
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