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| 1 | Addressing global change challenges for Central Asian socio-ecosystems显示文摘中亚是到全球气候变化的行星地球上的最脆弱的区域之一,取决于很易碎的自然资源。苏联遗产与一个高度综合的系统离开了五个国家(哈萨克斯坦, Tajikistan, Kyrgyzstan,土库曼斯坦,和乌兹别克) ,但是他们正在面对大挑战妨碍食物和水资源的地区性的协作的紧张。与增加气候可变性并且在这个区域温暖趋势,食物和水安全问题现在变得甚至更关键并且如果没适当地探讨,能影响地区性的稳定性。这二个很批评的元素,食物和水的长期的司机,是气候变化;立即并且可能影响食物和水安全的更激烈的因素是机构的变化和经济刺激驾驶的陆地使用。作为反馈,在陆地使用和陆地盖子的变化直接在这个区域穿上含意农村社区的水使用,食物生产,和生活方式。地区性、国际的努力被作了整体地理解原因,程度,率和土地的社会含意在这个区域使用变化。这些中的许多被理解,或在由各种各样的工程,而是开发答案的答案或研究努力的调查下面,到这些,迫切地区性的问题正在缺乏。这篇文章,用作特刊的介绍,提供在导致了这期特刊的出版物的地方面对中央亚洲国家和各种各样的国际努力的挑战的简短概述[出版摘要] | Jiaguo QI Temirbek S. BOBUSHEV Rashid KULMATOV Pavel GROISMAN Garik GUTMAN | 2012 | Frontiers of Earth Science2012，6，2： | 8 |
| 2 | Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment显示文摘The messenger RNA 3'-untranslated region(3'UTR)plays an important role in regulation of gene expres-sion on the posttranscriptional level. The 3'UTR con-trols gene expression via orchestrated interactionbetween the structural components of mRNAs(cis-ele-ment) and the specific trans-acting factors(RNA bind-ing proteins and non-coding RNAs). The crosstalk ofthese factors is based on the binding sequences and/or direct protein-protein interaction, or just functionalinteraction. Much new evidence that has accumulatedsupports the idea that several RNA binding factors canbind to common mRNA targets: to the non-overlappingbinding sites or to common sites in a competitive fash-ion. Various factors capable of binding to the sameRNA can cooperate or be antagonistic in their actions.The outcome of the collective function of all factorsbound to the same mRNA 3'UTR depends on manycircumstances, such as their expression levels, affinity to the binding sites, and localization in the cell, which can be controlled by various physiological conditions. Moreover, the functional and/or physical interactions of the factors binding to 3'UTR can change the character of their actions. These interactions vary during the cell cycle and in response to changing physiological condi-tions. Abnormal functioning of the factors can lead to disease. In this review we will discuss how alterations of these factors or their interaction can affect cancer development and promote or enhance the malignant phenotype of cancer cells. Understanding these altera-tions and their impact on 3'UTR-directed posttran-scriptional gene regulation will uncover promising new targets for therapeutic intervention and diagnostics. We will also discuss emerging new tools in cancer di-agnostics and therapy based on 3'UTR binding factors and approaches to improve them. | Andrii Vislovukh Thaiz Rivera Vargas Anna Polesskaya Irina Groisman | 2014 | World Journal of Biological Chemistry2014，5，1： | 6 |
| 3 | Understanding livestock production and sustainability of grassland ecosystems in the Asian Dryland Belt显示文摘Background:Companioned by economic development,a dietary shift toward higher meat consumption is seen in developing countries and transitional economies,where the demand for livestock production has been increasing in response to such a dietary shift.In the Asian Dryland Belt,approaches to meet this demand have focused on grazing intensification,cropland conversion for animal feed,and supplemental feeding.With the scarcity of water,energy,and food in the region,a key question is whether or not the current approaches are sustainable.If not,what are the pathways to increase livestock production while protecting the region’s environment for a sustainable future?We provide our reviews and discuss current approaches in response to these dietary shifts and assess their environmental resilience with a focus on the grassland ecosystems in the Asian Dryland Belt.Results:While current approaches alleviate the urgent need for short-term livestock production,they lead to longterm vulnerability in food security.Trade-offs between short gains and long-term losses,between food for humans and for animals,and between agricultural intensification and environmental degradation need to be holistically examined for the sustainable development of the region.A grassland water,energy,and food nexus framework is proposed with specific recommendations to increase livestock production while considering other ecosystem services of the dryland grassland ecosystems in the Asian Dryland Belt.Conclusions:Current practices to increase livestock production are likely to lead to long-term,large-scale ecological degradation of the grassland ecosystems in the Asian Dryland Belt and are thus unsustainable.By considering the trade-offs in the nexus of water,land,food,and livelihoods,sustainable pathways were articulated and recommended.Future pilot studies are needed for validation and adoption. | Jiaguo Qi Xiaoping Xin Ranjeet John Pavel Groisman Jiquan Chen | 2017 | Ecological Processes2017，6，1： | 4 |
| 4 | 上颌前牙区即刻种植修复的红白美学评分显示文摘目的:应用红色美学评分(PES)和白色美学评分(WES)评价上颌前牙即刻种植体与即刻修复的美学效果。材料与方法:回顾性分析患者资料。该评估由两名观察者使用12个评估标准进行。结果:在53名患者(22名男性与31名女性)的53例图像中,红色美学评分PES的均值为8.63±2.4(范围1-14),而白色美学评分WES均值为6.92±1.67(范围,2-10)。近中牙龈乳头得到最大的PES均值为(1.39±0.4)。远端牙龈乳头得到最小的PES均值(0.87±0.54)。牙齿表面得到最大的WES均值为(1.54土0.34)且牙齿形态得到最小的WES均值为(1.25土0.43)。结论:根据PES/WES值评估.针对上颌前牙,配合即刻修复的即刻种植体具有良好的临床美学效果。PES和WES评估值显示出较强的观察者本身差异一致性,但较弱的观察者间差异一致性。 | Guaracilei Maciel Vidigal Mario Groisman Victor Grover Rene Clavijo Igor Guimaraes Barros Paulinelli Santos Ricardo Guimaraes Fischer 杨宗澄(译) 徐新(审) | 2019 | 中国口腔医学继续教育杂志2019，22，2： | 3 |
| 5 | 在过去40年里出现的新趋势——北美持续旱段(英文)显示文摘在普遍增温的背景下,强降水过程中降水量不平衡增长(扩大植物生长期,加剧蒸腾作用)及降水总量的微弱改变将增加具有潜在威胁的极端气候事件——持续干期出现的频率。本文研究了过去几十年里,强降水过程出现频率发生改变的同一时期,这种趋势是否在北美北纬50。以南地区已经出现。同时,对日平均温度大于5℃,大量水分用于蒸腾的暖季及其给地面生态系统健康和农业带来巨大威胁的无降水期中,没有适量降水(〉1.0mm)的漫长干旱段进行了评价。在过去的四十年里,干旱段的平均持续时间显著延长,加拿大东南部持续20天以上,美国东部及沿墨西哥湾地区一个月以上,美国西南部及墨西哥北部2个月以上。因此,美国东部为期一个月的干旱段的重现期减少了一大半,从15年缩减到6~7年。在相对湿季里,大部分北纬55o南部的大陆上旱段的平均持续时间正在延长。但是,这一趋势并没有在美国的西北部及与加拿大接壤的南部地区发现。 | Pavel Ya. Groisman Richard W. Knight | 2007 | 地球科学进展2007，22，11： | 3 |
| 6 | Evaporation losing its strength显示文摘 | Peterson T C Golubev V S Groisman 19 Y | 1995 | Nature1995，377，： | 1 |
| 7 | Resistance to host antimicrobial peptides is nec- essary for Salmonella virulence显示文摘 | GROISMAN E A PARRA-LOPEZ C SALCEDO M | 1992 | Proc Natl Acad Sci U S A1992，89，11： | 1 |
| 8 | Ob served variability and trends in extreme climate events: A brief review显示文摘 | Easterlling D R Evans J L Groisman P Y | 2000 | Bullelin of the American Meteoro logical Society2000，81，41： | 1 |
| 9 | The Salmonella SpiC protein targets the mammalian HootG protein function to alter cellular traf licking显示文摘 | Shotland Y Kramer H Groisman EA | 2003 | Mol Microbiol2003，49，6： | 1 |
| 10 | Hamack Inequality for a Class of Degenerate Elliptic Operator 显示文摘 | FERNANDES J D GROISMAN J MELO S T | 2003 | Zeitschrift fur Analysis Und Ihre Anwendungen2003，22，1： | 1 |
| 11 | Ob- served variability and trends in extreme climate events: A brief review显示文摘 | Easterling D R Evans J L Groisman P Y | 2000 | Bulletin of the American Meteoro-logical Society2000，81，3： | 1 |
| 12 | Prolonged dry episodes over the conterminous United States:new tendencies emerging during the last 40 years显示文摘 | Groisman P Y R W Knight | | 0，，： | 1 |
| 13 | The secreted glycoprorein CREG enhances differentiation of NTERA-2 human embryo- nal carcinoma cells 显示文摘 | Veal E Groisman R Eisenstein M | 2000 | Oncogene2000，19，17： | 1 |
| 14 | Evaporation losing its strength显示文摘 | Peterson T C Golubev V S Groisman P Y | 1995 | Nature1995，337，： | 1 |
| 15 | Ewapomtion losing its strength 显示文摘 | Peterson Golubev Groisman | 1995 | Nature1995，，377： | 1 |
| 16 | The ubiquitin ligase activity in the ddb2 and csa complexes is differentially regulated by the cop9 signalosome in response to DNA damage显示文摘 | Groisman R Polanowska J Kuraoka I | 2003 | Cell2003，113，： | 1 |
| 17 | Observed variability and trends in extreme climate events:A brief review显示文摘 | Easterling D R Evans J L Groisman P Y | 2000 | Bulletin of the American Meteorological Society2000，81，： | 1 |
| 18 | Lateral gene trans- fer and the nature of bacterial innovation显示文摘 | Ochman H Lawrence JG Groisman EA | 2000 | Nature2000，405，5： | 1 |
| 19 | Evaporation changes over the contiguous United States and the former USSR:A reassessment显示文摘 | Valentin S Golubev Jay H Lawrimore Pavel Ya Groisman | 2006 | Geophysical Research Letters2006，28，13： | 1 |
| 20 | Evaporation losing its strength显示文摘 | Peterson T C Golubev V S Groisman P Y | 1995 | Nature1995，377，： | 1 |
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