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| 1 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 8 |
| 2 | Mosquito larvicidal properties of Ficus henghalensis L.(Family:Moraceae) against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi(Diptera:Culicidae)显示文摘Objective:To determine the larvicidal efficacy of different solvent leaf extract of Ficus benghalensis(F.benghalensis) against Culex tritaeniorhynchus(Cx.tritaeniorhynchus) and Anopheles subpictus(An.subpictus).Methods:Twenty five early third instar larvae of Cx. tritaeniorhynchus and An.subpictus were exposed to various concentrations and were assayed in the laboratory by using the protocol of WHO 2005.The larval mortality was observed after 24 h of treatment.Results:Among three solvent extracts tested the maximum efficacy was observed in the methanol extract.The LC50 and LC90 values of F.benghalensis against early third instar of Cx. tritaeniorhynchus and An.subpictus were 100.88.159.76 ppm and 56.66.85.84 ppm.respectively. No mortality was observed in controls.The chi-square values were significant at P<0.05 level. Conclusions:From the results it can be concluded the crude extract of F.benghalensis was an excellent potential for controlling Cx.tritaeniorhynchus and Art.subpictus mosquito larvae. | M Govindarajan R Sivakumar A Amsath S Niraimathi | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，7： | 3 |
| 3 | 焊接参数对搅拌摩擦焊接AA2219-T87材料韧性、洋葱圆环的断裂行为的影响(英文)显示文摘与熔焊相比,搅拌摩擦焊可以更好地保持材料的韧性和塑性,提高焊接的抗裂稳定性。本研究旨在提高焊接接头的延性和强度。刀具廓形在保持延性、分析金属流动行为和确定断裂起始点等方面起着重要作用。分析了洋葱圆环不同区域的微观结构,得出了洋葱圆环强度与金属流型的关系。结果表明,洋葱圆环强化了焊缝熔核。肩部和锥形螺纹型线刀具具有优异的力学性能。显微硬度数据表明,断口经过热影响区和热机械影响区等低硬度区。扫描电镜图像显示了细长的晶粒和韧窝,证实了断裂为韧性断裂。 | Dinesh KUMAR R S MUTHUKUMARAN Vincent XAVIER T VENKATESWARAN D SIVAKUMAR | 2019 | Journal of Central South University2019，26，9： | 2 |
| 4 | An elastoplastic critical state framework for unsaturated soil显示文摘 | WHEELER S J SIVAKUMAR V | 1995 | Geotechnique1995，45，1： | 1 |
| 5 | A systematic approach to noise reduction in observed chaotic time series显示文摘 | Sivakumar B Phoon K K Liong S Y | 1999 | Journal of Hydrology1999，219，34： | 1 |
| 6 | An Elasto -plastic CriticalState Framework for Unsaturated Soil显示文摘 | WHEELER S J SIVAKUMAR V | 1995 | C eotechnique1995，45，1： | 1 |
| 7 | Characterizations of diverse mole of pure and Ni-doped o-Fe, OJ synthesized nanoparticles through chemical precipitation route显示文摘 | Sivakumar S Anusuya D Khatiwada C P | 2014 | Spectrochimacta A2014，128，15： | 1 |
| 8 | A study on the design and behavior of 显示文摘 | Saravanan U Sivakumar S M Kalyanaraman V | | Smart Materials and Structures0，，： | 1 |
| 9 | The estimation of transpiration from sparse dryland millet using stomatal con cuctance and vegetation area indices 显示文摘 | Wallace J S Roberts J M Sivakumar M V K | 1990 | Agricutural forest meteorology1990，51，： | 1 |
| 10 | An elastoplastic critical state framework for unsaturated soil显示文摘 | WHEELER S J SIVAKUMAR V | 1995 | Geotechnique1995，45，1： | 1 |
| 11 | Tropical clays II : Engineering behavior显示文摘 | PANDIAN N S NAGARAJ T S SIVAKUMAR BABU G L | 1993 | Journal of Geotechnieai Engineering1993，119，： | 1 |
| 12 | Interactions of serum albumins with antitumor agent benzo phenazine -a spectroscopic study 显示文摘 | Sivakumar R Naveertraj S Anandan S | 2011 | J Lumin2011，131，10： | 1 |
| 13 | 显示文摘 | Yasodhai S Sivakumar T Govindarajan S | 1999 | Thermochimica Acta1999，338，： | 1 |
| 14 | Synthesis,antimyeobaeterial activity evaluation, and QSAR studies of chalcone derivatives 显示文摘 | P M Sivakumar S Prabu Seenivasan Vanaja Kumar Mukesh Doble | 2007 | Bioorganic & Medicinal Chemistry Letters2007，17，6： | 1 |
| 15 | Anthocyanin-rich sweet potato lacto-pickle: production, nutritional and proximate composition显示文摘 | PANDA S H PANDA S SIVAKUMAR P S | 2009 | International Journal of Food Science and Technology2009，44，： | 1 |
| 16 | Natural optima in human skull: a low-velocity impact study 显示文摘 | Anup S Sivakumar SM Suraishkumar GK | 2007 | In J Crashwor- thiness2007，12，1： | 1 |
| 17 | Silencing of midgut aminopep tidase-N of Spodoptera litura by Double-stranded RNA establishes its role as Bacillus thuringiensis toxin receptor显示文摘 | RAJAGOPAL R SIVAKUMAR S AGRAWAL N | 2002 | Biol Chem2002，277，46： | 1 |
| 18 | Seasonal variations in composting pro- cess of dead poultry birds显示文摘 | Sivakumar K Kumar V R S Jagatheesan P N R | 2008 | Bioresource Technology2008，99，： | 1 |
| 19 | Synthesis and anti- angiogenesis activity of coumarin derivatives 显示文摘 | Lee S Sivakumar K Shin W S | 2006 | Bioorganic & Medicinal Chemistry Letters2006，16，： | 1 |
| 20 | 显示文摘 | Malghan S G Wang P S Sivakumar A | 1993 | Compos Interface1993，1，3： | 1 |
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