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| 1 | Love and death: microglia, NLRP3 and the Alzheimer's brain显示文摘 | Tobias Goldmann Tuan LengTay Marco Prinz | 2013 | Cell Research2013，23，5： | 8 |
| 2 | Herb-induced liver injury: Systematic review and meta-analysis显示文摘BACKGROUND The use of herbal supplements and alternative medicines has been increasing in the last decades.Despite popular belief that the consumption of natural products is harmless,herbs might cause injury to various organs,particularly to the liver,which is responsible for their metabolism in the form of herb-induced liver injury(HILI).AIM To identify herbal products associated with HILI and describe the type of lesion associated with each product.METHODS Studies were retrieved using Medical Subject Headings Descriptors combined with Boolean operators.Searches were run on the electronic databases Scopus,Web of Science,MEDLINE,BIREME,LILACS,Cochrane Library for Systematic Reviews,SciELO,Embase,and Opengray.eu.Languages were restricted to English,Spanish,and Portuguese.There was no date of publication restrictions.The reference lists of the studies retrieved were searched manually.To access causality,the Maria and Victorino System of Causality Assessment in Drug Induced Liver Injury was used.Simple descriptive analysis were used to summarize the results.RESULTS The search strategy retrieved 5918 references.In the final analysis,446 references were included,with a total of 936 cases reported.We found 79 types of herbs or herbal compounds related to HILI.He-Shou-Wu,Green tea extract,Herbalife,kava kava,Greater celandine,multiple herbs,germander,hydroxycut,skullcap,kratom,Gynura segetum,garcinia cambogia,ma huang,chaparral,senna,and aloe vera were the most common supplements with HILI reported.Most of these patients had complete clinical recovery(82.8%).However,liver transplantation was necessary for 6.6%of these cases.Also,chronic liver disease and death were observed in 1.5%and 10.4%of the cases,respectively.CONCLUSION HILI is normally associated with a good prognosis,once the implied product is withdrawn.Nevertheless,it is paramount to raise awareness in the medical and non-medical community of the risks of the indiscriminate use of herbal products. | Vinícius Remus Ballotin Lucas Goldmann Bigarella Ajacio Bandeira de Mello Brandão Raul Angelo Balbinot Silvana Sartori Balbinot Jonathan Soldera | 2021 | World Journal of Clinical Cases2021，9，20： | 4 |
| 3 | Transgastric pancreatography and EUS-guided drainage of the pancreatic duct显示文摘 | Uwe Will Frank Fueldner Anne-Kathrin Thieme Bernhard Goldmann Rainer Gerlach Igor Wanzar Frank Meyer | 2007 | Journal of Hepato - Biliary - Pancreatic Surgery2007，，4： | 2 |
| 4 | National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales. | Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser | 2021 | Forest Ecosystems2021，8，1： | 2 |
| 5 | Quantitative determination of four nitrofuran metabolites in meat by isotope dilution liquid chromatography–electrospray ionisation–tandem mass spectrometry显示文摘 | Pascal Mottier Seu-Ping Khong Eric Gremaud Janique Richoz Thierry Delatour Till Goldmann Philippe A. Guy | 2004 | Journal of Chromatography A2004，，1： | 2 |
| 6 | Scoring the collective effects of SNPs: association of minor alleles with complex traits in model organisms显示文摘It has long been assumed that most parts of a genome and most genetic variations or SNPs are non-functional with regard to reproductive fitness.However,the collective effects of SNPs have yet to be examined by experimental science.We here developed a novel approach to examine the relationship between traits and the total amount of SNPs in panels of genetic reference populations.We identified the minor alleles(MAs)in each panel and the MA content(MAC)that each inbred strain carried for a set of SNPs with genotypes determined in these panels.MAC was nearly linearly linked to quantitative variations in numerous traits in model organisms,including life span,tumor susceptibility,learning and memory,sensitivity to alcohol and anti-psychotic drugs,and two correlated traits poor reproductive fitness and strong immunity.These results suggest that the collective effects of SNPs are functional and do affect reproductive fitness. | YUAN DeJian ZHU ZuoBin TAN XiaoHua LIANG Jie ZENG Chen ZHANG JieGen CHEN Jun MA Long DOGAN Ayca BROCKMANN Gudrun GOLDMANN Oliver MEDINA Eva RICE Amanda D. MOYER Richard W. MAN Xian YI Ke LI YanKe LU Qing HUANG YiMin HUANG Shi | 2014 | Science China(Life Sciences)2014，57，9： | 2 |
| 7 | Combination anesthesia with ketamlne and pentobarbital:a long-term porcine model显示文摘 | Goldmann C Ghofrani A Haferaann B | 1999 | Res Exp Med1999，199，1： | 1 |
| 8 | Cognitive impairment in Parkinson's disease and dementia with Lewy bodies:a spectrum of disease显示文摘 | Goldmann Gross R Siderowf A Hurtig HI | 2008 | Neurosignals2008，16，1： | 1 |
| 9 | Troponin:an important prognostic marker and risk-stratification tool in non-ST-segment elevation acute coronary syncdromes显示文摘 | Newby LK Goldmann BU Ohman EM | 2003 | J Am Coll Cardiol2003，41，4： | 1 |
| 10 | The classification and discrimination of glass fragments using non destructive energy dispersive X-ray microfluorescence显示文摘 | Hicks T Monard Sermier F Goldmann T | | 0，，2： | 1 |
| 11 | Microstream capnography improves patient monitoring during moderate sedation:a randomized,controlled trial显示文摘 | Lightdale JR Goldmann DA Feldman HA | | 0，，06： | 1 |
| 12 | Paired comparison- based subjective quality assessment of stereoscopic images 显示文摘 | Lee J S Goldmann L Ebrahimi T | 2013 | Multimedia Tools and Applications2013，67，1： | 1 |
| 13 | Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels, c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina ( CAPTURE ) Study Investigators 显示文摘 | Hamm C W Heeschen C Goldmann B | 1999 | N Engl J Med1999，340，： | 1 |
| 14 | Mechanical aspects of cell shape regulation and signaling显示文摘 | Goldmann W H | 2002 | Cell Biol Int2002，26，： | 1 |
| 15 | Mechanical aspects of cell shape regulation and signaling显示文摘 | Goldmann WH | 2002 | Cell Biology International2002，26，4： | 1 |
| 16 | Ventilation-in- duced activation of the mitogen-activated protein kinase pathway显示文摘 | Uhlig U Haitsma JJ Goldmann Y | 2002 | Eur Respir J2002，20，4： | 1 |
| 17 | Treponin concentrations for stratification of patients with acute coronary syndromes in relation to therapeutic efficacy of tirefiban 显示文摘 | Heeschen C Hamm C W Goldmann B | 1999 | Lancet1999，354，： | 1 |
| 18 | Novel polymorphisms in the caprine PrP gene: a codon 142 mutation associated with scrapie incubation period 显示文摘 | GOLDMANN W MARTIN T FOSTER J | 1996 | J Gen Virol1996，77，： | 1 |
| 19 | Contribution of natural killer cells to the pathogenesis of septic shock induced by Streptococcus pyogenes in mice显示文摘 | Goldmann O Chhatwal GS Medina E | 2005 | J Infect Dis2005，191，： | 1 |
| 20 | Nosocomial viral infections: recent developments and new strategies 显示文摘 | Goldmann DA | 2009 | Eur J Clin Microbiol Infect Dis2009，8，1： | 1 |
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