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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | New totally intracorporeal reconstructive approach after robotic total gastrectomy: Technical details and short-term outcomes显示文摘AIM To show outcomes of our series of patients that underwent a total gastrectomy with a robotic approach and highlight the technical details of a proposed solution for the reconstruction phase.METHODS Data of gastrectomies performed from May 2014 to October 2016, were extracted and analyzed. Basic characteristics of patients, surgical and clinical outcomes were reported. The technique for reconstruction(Parisi Technique) consists on a loop of bowel shifted up antecolic to directly perform the esophago-enteric anastomosis followed by a second loop, measured up to 40 cm starting from the esojejunostomy, fixed to the biliary limb to create an enteroenteric anastomosis. The continuity between the two anastomoses is interrupted just firing a linear stapler, so obtaining the Roux-en-Y by avoiding to interrupt the mesentery.RESULTS Fifty-five patients were considered in the present analysis. Estimated blood loss was 126.55 ± 73 m L, no conversions to open surgery occurred, R0 resections were obtained in all cases. Hospital stay was 5(3-17) d, no anastomotic leakage occurred. Overall, a fast functional recovery was shown with a median of 3(3-6) d in starting a solid diet.CONCLUSION Robotic surgery and the adoption of a tailored reconstruction technique have increased the feasibility and safety of a minimally invasive approach for total gastrectomy. The present series of patients shows its implementation in a western center with satisfying short-term outcomes. | Amilcare Parisi Francesco Ricci Alessandro Gemini Stefano Trastulli Roberto Cirocchi Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，23： | 4 |
| 3 | Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy显示文摘In recent years, some researchers have tried to find a way to improve the surgical identification of the lymphatic drainage routes and lymph node stations during radical gastrectomy, thus starting a new research frontier in this field called 'navigation surgery'. Among the different reported solutions, the introduction of the indocyanine green(ICG) has drawn attention for its characteristics, a fluorescence dye that can be detected in the near infrared spectral band(NIR). A fluorescence imaging technology has been integrated in the latest version of the Da Vinci robotic system and surgeons have extensively reported their experiences in colorectal and hepato-biliary surgery for tumors, vascular and lymphatic structures visualization. However, up to date, the combined use of fluorescence imaging and robotic technology has not been adequately investigated during lymphadenectomy in gastric cancer. | Jacopo Desiderio Stefano Trastulli AlessANDro Gemini Domenico Di Nardo Giorgio Palazzini Amilcare Parisi Vito D'ANDrea | 2018 | Chinese Journal of Cancer Research2018，30，5： | 3 |
| 4 | Provocative Mesenteric Angiography for Lower Gastrointestinal Hemorrhage: Results from a Single-institution Study显示文摘 | Charles Y. Kim Paul V. Suhocki Michael J. Miller Mazhar Khan Gemini Janus Tony P. Smith | 2010 | Journal of Vascular and Interventional Radiology2010，，4： | 2 |
| 5 | Antibiotic prophylaxis in patients with cirrhosis: Current evidence for clinical practice显示文摘Patients with cirrhosis show an increased susceptibility to infection due to disease-related immune-dysfunction.Bacterial infection therefore represents a common,often detrimental event in patients with advanced liver disease,since it can worsen portal hypertension and impair the function of hepatic and extrahepatic organs.Among pharmacological strategies to prevent infection,antibiotic prophylaxis remains the first-choice,especially in high-risk groups,such as patients with acute variceal bleeding,low ascitic fluid proteins,and prior episodes of spontaneous bacterial peritonitis.Nevertheless,antibiotic prophylaxis has to deal with the changing bacterial epidemiology in cirrhosis,with increased rates of gram-positive bacteria and multidrug resistant rods,warnings about quinolonesrelated side effects,and low prescription adherence.Short-term antibiotic prophylaxis is applied in many other settings during hospitalization,such as before interventional or surgical procedures,but often without knowledge of local bacterial epidemiology and without strict adherence to antimicrobial stewardship.This paper offers a detailed overview on the application of antibiotic prophylaxis in cirrhosis,according to the current evidence. | Alberto Ferrarese Nicola Passigato Caterina Cusumano Stefano Gemini Angelo Tonon Elton Dajti Giovanni Marasco Federico Ravaioli Antonio Colecchia | 2021 | World Journal of Hepatology2021，13，8： | 2 |
| 6 | Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors’ experience显示文摘 | Claudio Renzi Castellani Francesco Barberini Roberto Cirocchi Gemini Noya Boselli Parisi Corsi Desiderio Adriano Redler Trastulli Alberto Santoro | 2013 | 2013 (defa)2013，，： | 2 |
| 7 | A more meaningfol sonreing system for determining the severity of goronm'y heartdisease显示文摘 | Gemini GG | 1983 | Am J cardiol1983，51，： | 1 |
| 8 | Provocative Mesenteric Angiography for Lower Gastrointestinal Hemorrhage: Results from a Single-institution Study显示文摘 | Charles Y. Kim Paul V. Suhocki Michael J. Miller Mazhar Khan Gemini Janus Tony P. Smith | 2010 | Journal of Vascular and Interventional Radiology2010，，4： | 1 |
| 9 | Biodegradafion and detoxifieafion of P-nitrophenol by Rhodococcus wratislaviensis显示文摘 | Gemini V L Gallego A Oliveira V M | 2005 | International Biodeterioration Biodegradation2005，55，： | 1 |
| 10 | A more meaningful scoring system for determiningthe severity of coronary heart disease显示文摘 | Gemini GG | 1983 | Am J Cardiol1983，51，3： | 1 |
| 11 | A new generation of surfactants显示文摘 | Rosen M J Gemini | 1993 | Chemtech1993，，1： | 1 |
| 12 | Detoxification of 2, 4, 6-trichlorophenol by an indigenous bacterial community显示文摘 | Gallego A Gemini V Rossi S | 2009 | International Biodeterioration & Biodegradation2009，63，8： | 1 |
| 13 | Hepatic Venous Pressure Measurements: Comparison of End-Hole and Balloon Catheter Methods显示文摘 | Tony P. Smith Charles Y. Kim Alastair D. Smith Gemini Janas Michael J. Miller David R. Sopko Paul V. Suhocki | 2012 | Journal of Vascular and Interventional Radiology2012，，2： | 1 |
| 14 | Gender and peripheral neuropathy in chronic alcoholism;a clinical-electroneurographic study显示文摘 | Gemini D | 2000 | Alcohol Alcohol2000，35，4： | 1 |
| 15 | A more meaningful scoring system for determining the severity of coronary heart disease显示文摘 | Gemini GG | 1994 | AM J Cardiol1994，47，： | 1 |
| 16 | A new generation of surfactants 显示文摘 | Rosen M J Geminis | 1993 | J Am Chem Soc1993，23，3： | 1 |
| 17 | Biodegradation and detoxification of p-nitro phenol by Rhodococcus wratisla- viensis显示文摘 | GEMINI V L GALLEGO A OLIVEIRA V M | 2005 | International Biodeterioration & Biodegradation2005，55，2： | 1 |
| 18 | The role of gender and other factors as predictors of not receiving reperfusion ther- apy and of outcome in Stsegrnent elevation myocardial in- farction显示文摘 | Cohen M Gemini GF Maritz F | 2005 | J Thromb Thrombolysis2005，19，3： | 1 |
| 19 | Biodegra- dation and detoxiflcation ofp-nitrophenol by Rhodococcus wratislaviensis显示文摘 | GEMINI V L GALLEGO A DE OLIVEIRA V M | 2005 | International Biodeterioration Biodegra- dation2005，55，2： | 1 |
| 20 | determination and analysis of interfacial properties显示文摘 | Castro M J L Kovensky J Cirelli A F New family of nonionic gemini surfactants | 2002 | Langmuir2002，18，7： | 1 |
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