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43篇 您的检索式:作者名="Gehron"
    题名 作者 年代 出处 被引量
1Marrow stromal stem cells显示文摘Bianco P Gehron Robey P 0,,12:1
2FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting显示文摘Riminucci M Collins MT Fedarko NS Cherman N Corsi A White KE Waguespack S Gupta A Hannon T Econs MJ Bianco P Gehron Robey P 0,,:1
3Postnatal human dental pulp stem cells (DPSC) in vitro and in vivo 显示文摘Gronthos S Mankani M Gehron -Robey P 2000PNAS2000,97,13:1
4Gsα^(R201C)and estrogen reveal different subsets of bone marrow adiponectin expressing osteogenic cells显示文摘The Gsα/cAMP signaling pathway mediates the effect of a variety of hormones and factors that regulate the homeostasis of the post-natal skeleton.Hence,the dysregulated activity of Gsαdue to gain-of-function mutations (R201C/R201H)results in severe architectural and functional derangements of the entire bone/bone marrow organ.While the consequences of gain-of-function mutations of Gsαhave been extensively investigated in osteoblasts and in bone marrow osteoprogenitor cells at various differentiation stages,their effect in adipogenically-committed bone marrow stromal cells has remained unaddressed.We generated a mouse model with expression of Gsα^(R201C) driven by the Adiponectin(Adq)promoter.Adq-Gsα^(R201C) mice developed a complex combination of metaphyseal,diaphyseal and cortical bone changes.In the metaphysis,Gsα^(R201C) caused an early phase of bone resorption followed by bone deposition.Metaphyseal bone formation was sustained by cells that were traced by Adq-Cre and eventually resulted in a high trabecular bone mass phenotype.In the diaphysis,Gsα^(R201C),in combination with estrogen,triggered the osteogenic activity of Adq-Cre-targeted perivascular bone marrow stromal cells leading to intramedullary bone formation.Finally,consistent with the previously unnoticed presence of Adq-Cre-marked pericytes in intraosseous blood vessels,Gsα^(R201C) caused the development of a lytic phenotype that affected both cortical(increased porosity)and trabecular(tunneling resorption)bone.These results provide the first evidence that the Adq-cell network in the skeleton not only regulates bone resorption but also contributes to bone formation,and that the Gsα/cAMP pathway is a major modulator of both functions.Biagio Palmisano Rossella Labella Samantha Donsante Cristina Remoli Emanuela Spica Ilenia Coletta Giorgia Farinacci Michele Dello Spedale Venti Isabella Saggio Marta Serafini Pamela Gehron Robey Alessandro Corsi Mara Riminucci 2022Bone Research2022,10,4:1
5Investigation of multipotent postnatal stem cells from human periodontal ligament显示文摘Byoung-Moo Seo Masako Miura Stan Gronthos Peter Mark Bartold Sara Batouli Jaime Brahim Marian Young Pamela Gehron Robey Cun Yu Wang Songtao Shi 2004The Lancet2004,,9429:1
6Marrow stromal stem cells 显示文摘Bianco P Gehron Robey P 2000J Clin Invest2000,105,12:1
7Marrow stromal stem cells显示文摘Bianco P Gehron Robey P 2000J Clin Invest2000,05,12:1
8Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment显示文摘Benedetto Sacchetti Alessia Funari Stefano Michienzi Silvia Di Cesare Stefania Piersanti Isabella Saggio Enrico Tagliafico Stefano Ferrari Pamela Gehron Robey Mara Riminucci Paolo Bianco 2007Cell2007,,2:1
9Interference between pacemakers/implantable cardioverter defibrillators and video capsule endoscopy显示文摘Our Letter to the Editor, related to the article 'Small bowel capsule endoscopy in patients with cardiac pacemakers and implantable cardioverter defibrillators: Outcome analysis using telemetry' by Cuschieri et al , comments on some small errors, that slipped into the authors discussions. The given informations concerning the pacemakerand implantable cardioverter defibrillators modes were inaccurate and differ between the text and the table. Moreover, as 8 of 20 patient's pacemakers were programmed to VOO or DOO ('interference mode') and one patient was not monitored by telemetry during capsule endoscopy, 9 of 20 patients (45%) lack the informations of possible interference between capsule endoscopy their implanted device. Another objection refers to the interpretation of an electrocardiogram (figure 1, trace B) presented: in contrast to the author's opinion the marked spike should be interpreted as an artefact and not as 'undersensing of a fibrillatory wave'. Finally, three comments to cited reviews were not complete respectively not quoted correctly.Dirk Bandorski Johannes Gehron Reinhard Hltgen 2013World Journal of Gastrointestinal Endoscopy2013,5,4:1
10Marrow Stromal Stem Cells显示文摘Bianco P Gehron Pobey P 2000J Clin Invest2000,105,12:1
11Marrow stromal stem cells 显示文摘Bianco P Gehron Robey P 2000J Clin Invest2000,105,12:1
12Marrow stromal stem cells 显示文摘Bianco P & Gehron RP 2000Journal of Clinical Investigation2000,105,:1
13Marrow stromal stem cell显示文摘Bianco P Gehron RP 2000J clin Invest2000,105,12:1
14Expression of bone sialoprotein (BSP) in developing human tissues显示文摘Paolo Bianco Larry W. Fisher Marian F. Young John D. Termine Pamela Gehron Robey 1991Calcified Tissue International1991,,6:1
15Simmons Mesenchymal Stem Ceils: Revisiting History, Concepts, and Assays 显示文摘Paolo Bianco Pamela Gehron Robey Paul J 2008Cell Stem Cell2008,4,2:1
16Marrow stromal stem cel s显示文摘Bianco P Gehron Robey P 0,,12:1
17In vivo formation of bone and haematopoietic territories by transplanted human bone marrow stromal cells generated in medium with and without osteogenic supplements显示文摘Sergei A. Kuznetsov Mahesh H. Mankani Pamela Gehron Robey 2011J Tissue Eng Regen Med2011,,3:1
18Cloning and sequence analysis of bovine bone sialoprotein cDNA:conservation of acidic domains,tyrosine sulfation consensus repeats and RGD cell attachment domain显示文摘Chenu C Ibaraki K Gehron Robey P 1994J Bone Miner Res1994,9,3:1
19Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells 显示文摘Riminucci M Gehron RP Saggio I 2010J Mol Endocrinol2010,45,6:1
20Marrow stromal stem cells显示文摘Bianco P Gehron Robey P 2000J Clin Invest2000,105,12:1
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