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| 1 | Irradiation uniformity at the Laser MegaJoule facility in the context of the shock ignition scheme显示文摘The use of the Laser MegaJoule facility within the shock ignition scheme has been considered. In the first part of the study, one-dimensional hydrodynamic calculations were performed for an inertial confinement fusion capsule in the context of the shock ignition scheme providing the energy gain and an estimation of the increase of the peak power due to the reduction of the photon penetration expected during the high-intensity spike pulse. In the second part, we considered a Laser MegaJoule configuration consisting of 176 laser beams that have been grouped providing two different irradiation schemes. In this configuration the maximum available energy and power are 1.3 MJ and 440 TW. Optimization of the laser–capsule parameters that minimize the irradiation non-uniformity during the first few ns of the foot pulse has been performed. The calculations take into account the specific elliptical laser intensity profile provided at the Laser MegaJoule and the expected beam uncertainties. A significant improvement of the illumination uniformity provided by the polar direct drive technique has been demonstrated. Three-dimensional hydrodynamic calculations have been performed in order to analyse the magnitude of the azimuthal component of the irradiation that is neglected in twodimensional hydrodynamic simulations. | Mauro Temporal Benoit Canaud Warren J. Garbett Rafael Ramis Stefan Weber | 2014 | High Power Laser Science and Engineering2014，2，2： | 3 |
| 2 | Tumor targeted mesoporous silica-coated gold nanorods facilitate detection of pancreatic tumors using Multispectral optoacoustic tomography显示文摘Multispectral optoacoustic 断层摄影术(MSOT ) 是在传统的形式上提供几个优点的一种新兴的成像技术,特别地处于它解决在显微镜的规模上的深度的光对比的能力。当潜在的应用包括临床的阀值由当前的技术设置了的下面的肿瘤的早察觉时,肿瘤特定的对比代理人的缺乏限制 MSOT 成像的使用。因此,我们与 polyacrylic 酸(泛美航空公司) 或 aminefunctionalized mesoporous 硅石(MS ) 由涂层金牌 nanorods (GNR ) 构造了高度稳定的 nano 对比代理人。Syndecan-1,被显示了指向像胰岛素的生长因素 1 受体(IGF1-R )( 在胰腺的肿瘤的 upregulated ) ,在泛美航空公司涂的 GNR (PAA-GNRs ) 或 MS 涂的 GNR (MS-GNRs ) 的表面上被结合创造指向肿瘤的 nanoparticles。在 vitro, nanoparticles 指向的肿瘤与流动 cytometry 被估计。在 S2VP10L 房间(为 IGF1-R 积极) , syndecan-1 MS-GNRs (Syndecan-MS-GNRs ) 在 OA 信号表明了增加, 10x,与 syndecan-1 PAAGNR (Syndecan-PAA-GNRs ) 相比。最小的绑定在 MiaPaca-2 房间被观察(为 IGF1-R 否定) 。在 vivo,肿瘤 Syndecan-MS-GNRs 的特定的指向用鼠科的 orthotopic 被评估胰腺的癌症模型。Syndecan- MS-GNRs 比在象肝那样的离开目标机关在胰腺的肿瘤以内表明了显著地更大的累积。与 IGF1-R 否定 MiaPaca-2 房间植入的老鼠没表明指向的特定的肿瘤。在摘要,我们报导指向的 nano 对比代理人(Syndecan-MS-GNRs ) 能成功地检测 orthotopic 有在用 MSOT 的 vivo 有约束力的最小的离开目标的胰腺的肿瘤。 | Anil Khanal Christopher Ullum Charles W Kimbrough Nichola C. Garbett Joseph A. Burlison Molly W. McNally Phillip Chuong Ayman S. EI-Baz Jacek B. Jasinski Lacey R. McNally | 2015 | Nano Research2015，8，12： | 2 |
| 3 | An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer显示文摘 | Fiona J. Collinson David G. Jayne Alessio Pigazzi Charles Tsang Jennifer M. Barrie Richard Edlin Christopher Garbett Pierre Guillou Ivana Holloway Helen Howard Helen Marshall Christopher McCabe Sue Pavitt Phil Quirke Carly S. Rivers Julia M. B. Brown | 2012 | International Journal of Colorectal Disease2012，，2： | 2 |
| 4 | Enrich-ment of microsatellite from the citrus genome using bi-otinylated oligonucleotide sequence bound to strepta-vidin-coated magnetic particles显示文摘 | KIJAS J M FOWLER J C GARBETT C A | 1994 | Biotechniques1994，16，4： | 1 |
| 5 | Proteolysis in colorectal cancer显示文摘 | Garbett E A Reed M W R Brown N J | 1999 | J Clin Pathol: Mol Pathol1999，52，3： | 1 |
| 6 | Proteolysis in human breast and colorectal cancer显示文摘 | Garbett EA | 1999 | Br J Cancer1999，81，2： | 1 |
| 7 | An investigation into the application of floating reed bed and barley straw techniques for the remediation of eutrophic waters显示文摘 | Garbett P | 2005 | Water and Environment Journal2005，19，3： | 1 |
| 8 | Proteolysis in human breast cancer 显示文摘 | Garbett E A Reed M W Stephenson T J | 2000 | Mol Pathol2000，53，2： | 1 |
| 9 | Polar direct drive illumination uniformity provided by the Orion facility显示文摘 | Mauro Temporal Benoit Canaud Warren J. Garbett Franck Philippe Rafael Ramis | 2013 | The European Physical Journal D2013，，10： | 1 |
| 10 | Circular dichroism to determine binding mode and affinity of ligand-DNA interactions 显示文摘 | Garbett NC Ragazzon PA Chaires JB | 2007 | Nat Protoc2007，2，： | 1 |
| 11 | Opioid and nonopioid analgesics显示文摘 | SCHUG S A GARBETT W R GILLESPIE G | 2003 | Best Pract Res Clin Anaesthesiol2003，17，1： | 1 |
| 12 | Proteolysis in colorectal cancer显示文摘 | Garbett E A Reed M W R Brown N J | 1999 | Mol Pathol1999，52，3： | 1 |
| 13 | Synthesis and biological evaluation of bisindenoisoquinolines as topoisomerase I inhibitors显示文摘 | Nagarajan M Morrell A Antony S Kohlhagen G Agama K Pommier Y Ragazzon P.A Garbett N.C Chaires J.B Hollingshead M Cushman M | | 0，，17： | 1 |
| 14 | Disruption of cerebral cortex MET signaling in autism spectrum disorder 显示文摘 | Campbell D B D'Oronzio R Garbett K | 2007 | Ann Neurol2007，62，3： | 1 |
| 15 | Proteolysis in human breast and colorectal cancer显示文摘 | Garbett EA Reed MW Brown NJ | 1999 | Br J Cancer1999，81，2： | 1 |
| 16 | Proteolysis in colorectal cancer显示文摘 | Garbett E A Reed M W R Brown N J | 1999 | J Clin Pathol:Mol Pathol1999，52，3： | 1 |
| 17 | Maternal immuneactivation alters fetal brain development throughinterleukin-6显示文摘 | Smith SEP Li J Garbett K | 2007 | J Neuroscience2007，27，10： | 1 |
| 18 | An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer显示文摘 | Fiona J. Collinson David G. Jayne Alessio Pigazzi Charles Tsang Jennifer M. Barrie Richard Edlin Christopher Garbett Pierre Guillou Ivana Holloway Helen Howard Helen Marshall Christopher McCabe Sue Pavitt Phil Quirke Carly S. Rivers Julia M. B. Brown | 2012 | International Journal of Colorectal Disease2012，，2： | 1 |
| 19 | Proteolysis in human breast cancer 显示文摘 | Reed MW Stephenson TJ | 2000 | Mol Pathol2000，53，2： | 1 |
| 20 | Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression显示文摘 | Garbett KA Vereczkei A Kálmán S | 2015 | Biol Psychiatry2015，77，3： | 1 |
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