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| 1 | 基于ICF核心分类集类目开发临床等级评定量表显示文摘目的本研究在急性期医院背景下,就上下肢的移动性为例,目的是检验ICF类目的临床评定等级是否能够整合成一种多参数的等级评定量表,并且该量表能够根据特定患者的临床问题和康复目标提供有效可靠的临床评估。方法对急性期医院患有肌肉骨骼系统疾病的患者采用多中心前瞻性队列心理测量方法对数据进行统计分析。结果 234例肌肉骨骼状况患者(平均年龄56岁,50%女性。44%患者诊断涉及下肢,18%患者诊断涉及髋关节,18%患者诊断涉及上肢,16%患者诊断涉及脊柱)。调整不同测量功能项目之后,建立针对上肢或下肢功能的两个独立量表。建立的量表中有10个(上肢)和8个(下肢)测试项目有很好的拟合度。结论本研究的结果表明可基于ICF的核心分类集类目来开发等级评定量表。这可能是一个有希望的方法,因为在现有的领域里从心理测量方面来讲还没有可靠的测量方法。 | Eva Grill Gerold Stucki 王朴(译) 陈迪 田峻(译) 邱卓英(审校) 张爱民(审校) | 2011 | 中国康复理论与实践2011，17，2： | 5 |
| 2 | Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer显示文摘AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality. | Mohamad A Mouchli Lidia Ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman | 2018 | World Journal of Gastroenterology2018，24，8： | 5 |
| 3 | A LIM Domain Protein from Tobacco Involved in Actin-Bundling and Histone Gene Transcription显示文摘从植物(秘鲁利玛机场之代号) 的二秘鲁利玛机场之代号包含域的蛋白质典型地展出双 cytoplasmicnuclear 分布,建议除了他们在肌动朊细胞骨架组织的以前描述的角色,他们参予原子过程。用针对识别绑种 histone 基因倡导者的因素的一幅西南的基于污点的屏幕,我们孤立包含烟草秘鲁利玛机场之代号蛋白质 WLIM2 (NtWLIM2 ) 的积极克隆 cDNA。用两块草地荧光灯蛋白质(GFP ) 基于熔化、基于免疫学的策略,我们提供 NtWLIM2 本地化到肌动朊细胞骨架,原子核,和核的清楚的证据。有趣地,由 latrunculin B 的肌动朊细胞骨架的混乱显著地增加 NtWLIM2 原子部分,指出可能的新奇 cytoskeletalnuclear 串音。生物化学并且电子显微镜学实验揭示 NtWLIM2 的能力直接把后者绑在肌动朊细丝并且到交叉连接进厚肌动朊捆。NtWLIM2 明确地绑在 Arabidopsis histone H4A748 基因倡导者的保存 octameric cis 元素(10 月) 并且这绑定大部分依靠两个秘鲁利玛机场之代号领域的 Electrophoretic 活动性移动试金表演。重要地,在 Arabidopsis 和烟草原物进行的基于记者的实验证实 NtWLIM2 的能力绑在并且在实时房间激活 H4A748 基因倡导者。表示研究在烟草 BY-2 房间增长和房间周期前进期间显示 NtWLIM2 mRNA 和 NtWLIM2 蛋白质的组成的存在,建议在基础 histone 基因表示的激活的 NtWLIM2 的一个角色。有趣地,两个都生活房间并且在 vitro 数据支持 NtWLIM2 di/oligomerization。我们建议 NtWLIM2 作为稳定肌动朊的蛋白质工作,它在改变的细胞骨架之上,梭到原子核以便修改基因表示。 | Danièle Moes Sabrina Gatti CEline Hoffmann Monika Dieterle Flora Moreau Katrin Neumann Marc Schumacher Marc Diederich Erwin Grill Wen-Hui Shen André Steinmetz Cldment Thomas | 2013 | Molecular Plant2013，6，2： | 2 |
| 4 | Wear resistant fluorinated diamond-like carbon films显示文摘 | Donnet C Fontaine J Grill A | 1997 | Surface and Coating Technology1997，94，： | 2 |
| 5 | Algae sequester heavy metals via synthesis of phytochelatin complexes显示文摘 | Walter Gekeler Erwin Grill Ernst-Ludwig Winnacker Meinhart H. Zenk | 1988 | Archives of Microbiology1988，，2： | 2 |
| 6 | Characterization of fructose 6 phosphate phosphoketolases purified from Bifidobaeterium species 显示文摘 | Grill JP Crociani J Ballongue J | 1995 | Current Microbiology1995，31，1： | 1 |
| 7 | Clinical implications of defining the gross tumor volume with combination of CT and 18FDG- positron emission tomography in non- small- cell lung cancer显示文摘 | Grills I S Yah D Black Q C | 2007 | Int J Radiat Oncol Biol Phys2007，67，3： | 1 |
| 8 | NT-3 gene delivery elicitsgrowth of chronically injured corticospinal axons and modestly improves functional deficits after chronic scar resection显示文摘 | Tuszynski MH Grill R Leonard LL | 2003 | Exp Neurol2003，181，1： | 1 |
| 9 | Butterfly, Spider, and Plant Communities in Different Land-Use Types in Sardina,ha- ly 显示文摘 | GRILL A KNOFLACH B CLEARY D F R | 2005 | Biodiversity and Conservation2005，14，5： | 1 |
| 10 | Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma显示文摘 | Grill J Puget S Andreiuolo F | 2012 | Pediatr Blood Cancer2012，58，4： | 1 |
| 11 | Purification and characterization of conjugated BSH from Bifidobacterium longum BB536显示文摘 | Grill J Schneider F Crociani J | | 0，，07： | 1 |
| 12 | Defining a radiotherapy target with positron emission tomography显示文摘 | Black QC Grills IS Kestin LL | | 0，，04： | 1 |
| 13 | Correction of clubfoot relapse using Ilizarov,s apparatus in children 8-15 years old显示文摘 | Franke J Grill F Hein G | 1990 | Arch Orthop Trauma Surg1990，110，1： | 1 |
| 14 | Applied electric fields accelerate the diffusion rate and increase the diffusion distance of DiI in fixed tissue 显示文摘 | Swift MJ Crago PE Grill WM | 2005 | J Neurosci Methods2005，141，1： | 1 |
| 15 | Adhesion of different bifidobacteria strains to human enterocyte-like Caco-2 cells and comparison with in vivo study 显示文摘 | Crociani J Grill J P Huppert M | 1995 | Appl Microbiol1995，21，： | 1 |
| 16 | Evidance against an interaction between the mRNA downstream box and 16SrRNA in translation initiation显示文摘 | Moll I Huber M Grill S | 2001 | Journal of Bacteriology2001，11，183： | 1 |
| 17 | Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease 显示文摘 | Carlsen SM Foiling I Grill V | 1997 | Scand J Clin Lab Invest1997，57，6： | 1 |
| 18 | Hypercalcemia of malignancy 显示文摘 | Grill V Martin T | 2000 | Rev Endocr Metab Disord2000，1，4： | 1 |
| 19 | Outcomes after stereotacticlung radiotherapy or wedge resection for stage I non-small-cell lungcancer显示文摘 | Grills I Mangona V Welshe R | 2010 | J Clin Oncol2010，28，： | 1 |
| 20 | Validation of Inter- national Classification of Functioning, Disability, and Health (ICF) Core Sets for early postacute rehabilitation fa- cilities: comparisons with three other functional measures 显示文摘 | Grill E Stucki G Scheuringer M | 2006 | Am J Phys Med & Rehabil2006，85，8： | 1 |
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