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331篇 您的检索式:作者名="GALLEGO S"
    题名 作者 年代 出处 被引量
1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Accuracy of Magnetic Resonance Enterography in Assessing Response to Therapy and Mucosal Healing in Patients With Crohn’s Disease显示文摘Ingrid Ordás Jordi Rimola Sonia Rodríguez José M. Paredes María J. Martínez-Pérez Esther Blanc Juan A. Arévalo Marta Aduna Montserrat Andreu Alexander Radosevic Anna M. Ramírez-Morros Susana Pinó Marta Gallego Aranzazu Jauregui-Amezaga Elena Ricart Julián 2013Gastroenterology2013,,:3
3Risk of developing tuberculosis under anti-TNF treatment despite latent infection screening显示文摘Aranzazu Jauregui-Amezaga Fanny Turon Ingrid Ordás Marta Gallego Faust Feu Elena Ricart Julián Panés 2012Journal of Crohn’s and Colitis2012,,:2
4Community structure and PAH ring-hydroxylating dioxygenase genes of a marine pyrene-degrading microbial consortium显示文摘GALLEGO S VILA J TAULER M 2014Biodegradation2014,25,4:1
5Toughening of PA6/mEPDM Blends by Two Methods of Compounding, Extruder and Internal Mixer: Rheological, Morphological and Mechanical Characterization显示文摘R Gallego D Garc A-L Pez S L Pez-quintana 2008Poly- mer Bulletin2008,60,:1
6Cadmium toxicity in plants显示文摘Benavides M Gallego S Tomaro M 2005Brazilian Journal of Plant Physiology2005,17,1:1
7A role for glutamate decarboxylase during tomato ripening:the characterisation of a cDNA encoding a putative glutamate decarboxylase with a calmodulin-binding site显示文摘Gallego P P Whotton L Picton S 1995Plant Molecular Biology1995,27,6:1
8The social network of a cell:recent advances in interactome mapping显示文摘Charbonnier S Gallego O 0,,5:1
91-Deoxy-D-xy- lulose 5-phosphate reductoisomerase and plastid isoprenoid biosyn- thesis during tomato fruit ripening 显示文摘RODRtGUEZ-CONCEPCION M AHUMADA I DIEZ-JUEZ E SAURET-GUETO S MARIA LOIS L GALLEGO F CAR- RETERO-PAULET L CAMPOS N BORONAT A 2001Plant J2001,27,3:1
10Effect of heavy metal ion excess on sunflower leaves :evidence for involvement of oxidative stress 显示文摘GALLEGO S M BENAVIDEs MP TOMARO M L 1996Plant Sci1996,121,:1
11Simplified method for the determination of chlorinated fungicides and insecticides in fruits by gas chromatography显示文摘COLUME A CARDENAS S GALLEGO M 2000J Chromatogr A2000,882,:1
12Cyelooxygenase-2 (COX-2):a molecular target in prostate cancer 显示文摘Aparieio Gallego G Diaz Prado S Jimenez Fonseea P 2007Clin Transl Oneol2007,9,11:1
13Prognostic influence of p53 nuclear overexpression in colorectal carcinoma显示文摘Gallego MG Acenero MJ Ortega S 2000Dis Colon Rectum2000,43,7:1
14Influ- ence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers 显示文摘Lopez - Rodrlguez R Novalbos J Gallego - Sandfn S 2008Pharmacol Res2008,58,:1
15Impact of fracture coating on fracture/matrix interactions in unsaturated porous medi显示文摘Thoma S G Gallegos D P Smith D M 1992Water Resources Research1992,28,:1
16Fully automated quantitation of hepatitis B virus (HBV) DNA in human plasma by the COBAS AmpliPrep/COBAS TaqMan system显示文摘Hochberger S Althof D Gallegos de Schrott R 2006J Clin Virol2006,35,4:1
17The start of renal replacement therapy in a Spanish 显示文摘Castellano I Gallego S Labrador PJ 2006Nefrologia2006,26,4:1
18Use of high resolution imagery and ground survey data for estimating crop areas in Mengcheng county, China显示文摘H Kerdiles Q Dong S Spyratos F J Gallego 2014IOP Conference Series: Earth and Environmental Science2014,,1:1
19Effect of collection zone height and operating variables on recovery of overload flotation columns 显示文摘Garibay R P Gallegos A P M Uribe S A 2002Minerals Engineering2002,15,:1
20Effect of cadmium stress on nitrogen metabolism in nodules and roots of soybean plants 显示文摘Balestrasse K B Benavides M P Gallego S M 2003Function Plant Biology2003,30,:1
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