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| 1 | Post-traumatic hepatic artery pseudoaneurysm treated with endovascular embolization and thrombin injection显示文摘Post-traumatic hepatic artery pseudoaneurysm is unc-ommon,appearing in approximately 1%of hepatic trauma cases.Most are extrahepatic(80%)and have a late onset.Although they are usually asymptomatic, they should always be treated becasue of the high risk of complications,especially breakage.Currently the treatment of choice is endovascular embolization with coils or the exclusion of the pseudoaneurysm using other intravascular devices.Recently there have been accounts of a treatment that combines embolization with coils and image-guided percutaneous human thrombin injection.We present a case of post-traumatichepatic artery pseudoaneurysm that was successfully treated using this combined technique. | Lloret Esta Francisco López Conesa Asunción Capel Alemán Antonio Robles Campos Ricardo Reus Pintado Manuel Marín Hernández Caridad | 2010 | World Journal of Hepatology2010，2，2： | 9 |
| 2 | Helicobacter pylori and EBV in gastric carcinomas:Methylation status and microsatellite instability显示文摘AIM:To verify the methylation status of CDH1, DAPK, COX2, hMLH1 and CDKN2A genes and to evaluate their association with Helicobacter pylori (H. pylori)-cagA+ and Epstein Barr virus (EBV) infections in gastric adenocarcinomas.METHODS: Methylation-specific PCR (MSP) assay was performed in 89 primary gastric carcinomas (intestinal and diffuse types). Microsatellite instability (MSI) analysis was performed using the BAT26 primer set and PCR products were analyzed with the ABI PRISM 3100 Genetic Analyzer using Genescan 3.7 software (Applied Biosystems). Detection of H. pylori and genotyping were performed by PCR, using specifi c primers for ureaseC and cagA genes. The presence of EBV was assessed by in situ hybridization. Statistical analyses were performed using the χ2 or Fisher's exact test.RESULTS: The most frequent hypermethylated gene was COX-2 (63.5%) followed by DAPK (55.7%), CDH1 (51%), CDKN2A (36%) and hMLH1 (30.3%). Intestinal and diffuse adenocarcinomas showed different methylation profiles and there was an association between methylation of E-CDH1 and H. pylori-cagA+ in the intestinal adenocarcinoma type. MSI was correlated with hMLH1 methylation. There was an inverse correlation between DAPK hypermethylation and MSI.CONCLUSION: We found a strong association between CDH1 methylation and H. pylori-cagA+ in intestinal-type gastric cancer, association of MSI and better prognosis and an heterogeneous COX-2 overexpression. | Adriana Camargo Ferrasi Nídia Alice Pinheiro Silvia Helena Barem Rabenhorst Otávia Luisa Caballero Maria Aparecida Marchesan Rodrigues Fabrício de Carvalho Celso Vieira de Souza Leite Marcia Valéria Pitombeira Ferreira Marcos Aurélio Pessoa Barros Maria Inês de Moura Campos Pardini | 2010 | World Journal of Gastroenterology2010，16，3： | 6 |
| 3 | New insights into the pathophysiology of achalasia and implications for future treatment显示文摘Idiopathic achalasia is an archetype esophageal motor disorder, causing significant impairment of eating ability and reducing quality of life. The pathophysiological underpinnings of this condition are loss of esophageal peristalsis and insufficient relaxation of the lower esophageal sphincter(LES). The clinical manifestations include dysphagia for both solids and liquids, regurgitation of esophageal contents, retrosternal chest pain, cough, aspiration, weight loss and heartburn. Even though idiopathic achalasia was first described more than 300 years ago, researchers are only now beginning to unravel its complex etiology and molecular pathology. The most recent findings indicate an autoimmune component, as suggested by the presence of circulating anti-myenteric plexus autoantibodies, and a genetic predisposition, as suggested by observed correlations with other well-defined genetic syndromes such as Allgrove syndrome and multiple endocrine neoplasia type 2 B syndrome. Viral agents(herpes, varicella zoster) have also been proposed as causative and promoting factors. Unfortunately, the therapeutic approaches available today do not resolve the causes of the disease, and only target the consequential changes to the involved tissues, such as destruction of the LES, rather than restoring or modifying the underlying pathology. New therapies should aim to stop the disease at early stages, thereby preventing the consequential changes from developing and inhibiting permanent damage. This review focuses on the known characteristics of idiopathic achalasia that will help promote understanding its pathogenesis and improve therapeutic management to positively impact the patient's quality of life. | Janette Furuzawa-Carballeda Samuel Torres-Landa Miguel ángel Valdovinos Enrique Coss-Adame Luis A Martín del Campo Gonzalo Torres-Villalobos | 2016 | World Journal of Gastroenterology2016，22，35： | 4 |
| 4 | Effect of Helicobacter pylori Infection on Growth Velocity of School-age Andean Children显示文摘 | Karen J. Goodman Pelayo Correa Robertino Mera Maria C. Yepez Cristina Cerón Cristina Campo Nancy Guerrero Mónica S. Sierra Luis E. Bravo | 2011 | Epidemiology2011，，1： | 2 |
| 5 | Treatment of anaerobic sludge digester effluents by the CANON process in an air pulsing SBR显示文摘 | J.R. Vázquez-Padín M.J. Pozo M. Jarpa M. Figueroa A. Franco A. Mosquera-Corral J.L. Campos R. Méndez | 2008 | Journal of Hazardous Materials2008，，1： | 2 |
| 6 | Perspectives of the potential implications of wine polyphenols on human oral and gut microbiota显示文摘 | T. Requena M. Monagas M.A. Pozo-Bayón P.J. Martín-álvarez B. Bartolomé R. del Campo M. ávila M.C. Martínez-Cuesta C. Peláez M.V. Moreno-Arribas | 2010 | Trends in Food Science & Technology2010，，7： | 2 |
| 7 | sTWEAK is a marker of early haematoma growth and leukoaraiosis in intracerebral haemorrhage显示文摘Objective To study the association between early growth of haematoma with biomarkers of endothelial dysfunction such as leukoaraiosis(LA)and the soluble tumour necrosis factor-like weak inducer of apoptosis(sTWEAK)in patients with intracerebral haemorrhage(ICH).Methods This is a retrospective observational study of patients with nontraumatic ICH.Clinical and biochemical parameters were analysed.sTWEAK levels were measured by ELISA.LA was analysed in the hemisphere without haemorrhage to avoid interference with the acute injury.The main endpoint was the haematoma growth evaluated by the difference in volume between the second and the initial neuroimage.Poor functional outcome,defined as a modified Rankin Scale>2 at 3 months,was considered as secondary endpoint.Receiver operating characteristic curve analysis was performed to stablish the best cut-off for sTWEAK levels associated with haematoma growth.Results We included 653 patients with ICH in our analysis(71.1±11.9 years,44%women).Haematoma growth was observed in 188 patients(28.8%).sTWEAK levels≥5600 pg/mL predicted ICH growth with a sensitivity of 84%and a specificity of 87%.sTWEAK levels≥5600 pg/mL and the presence of LA were associated with haematoma growth(OR:42.46;(CI 95%22.67 to 79.52)and OR:2.73(CI 95%1.39 to 5.34),respectively).Also,the presence of LA(OR:4.31(CI 95%2.89 to 6.42))and the interaction between ICH growth and sTWEAK(OR:2.23(CI 95%1.40 to 3.55))were associated with poor functional outcome at 3 months.Conclusion sTWEAKs,together with the presence and grade of LA,are biomarkers able to predict ICH growth and poor functional outcome in patients with ICH. | Andrés da Silva-Candal Iria López-Dequidt Manuel Rodriguez-Yañez PauloÁvila-Gómez JoséManuel Pumar JoséCastillo Tomás Sobrino Francisco Campos Ramón Iglesias-Rey Pablo Hervella | 2021 | Stroke & Vascular Neurology2021，6，4： | 2 |
| 8 | Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers显示文摘瞄准:分析在肝的 anti-HBs 的存在是否移植接受者在阻止 HBV 感染是有效的。方法:23 个病人收到 anti-HBc 积极的肝被学习。九个接受者是由于以前的 HBV 感染积极的 anti-HBc。他们,一个人也收到了在肝前移植时期期间疫苗的 HBV。十四个接受者是由于在预先移植经期期间管理的 HBV 疫苗积极的 anti-HBs。肝活体检视在 10/14 anti-HBc negative/anti-HBs 被获得积极接受者并且在 4/9 anti-HBc 积极接受者。结果:在 46 个月的一个吝啬的后续时期以后,有保护的浆液 anti-HBs 层次的 1 个接受者作为有免疫力的逃跑 HBV 异种的后果得了 de novo HBV 感染。在 14 之中种牛痘的 anti-HBc negative/anti-HBs 积极接受者,有可得到的肝活体检视(10%) 的 1/10 病人在 13 瞬间有肝 HBV-DNA 没有浆液的肝以后的移植病毒的标记并且没得 de novo HBV 感染。种牛痘的 anti-HBc 没有 HBV 疫苗的反应的积极接受者是在浆液和肝积极的 HBV-DNA,病毒的 DNA 在下列测试是连续地否定的,自发的 seroconversion 因此被诊断。结论:由于 HBV 疫苗或过去的 HBV 感染的 anti-HBs 的存在似乎在保护从 anti-HBc 收到肝的病人有效积极施主。然而,有免疫力的逃跑 HBV 异种的出现,能躲避 anti-HBs 保护,应该被看作 HBV 感染的风险。 | Rafael Barcena Gloria Moraleda Javier Moreno M Dolores Martín Emilio de Vicente Jesús Nuo M Luisa Mateos Santos del Campo | 2006 | World Journal of Gastroenterology2006，12，13： | 2 |
| 9 | Chronic hepatitis induced by Jin Bu Huan显示文摘 | Picciotto A Campo N Brizzolara R | 1998 | J Hepatol1998，28，： | 1 |
| 10 | Targeting and topology in the membrane of plant 3-hydroxy-3-methylglutaryl coen- zyme A reductase显示文摘 | Campos N Boronat A | 1995 | Plant Cell1995，7，12： | 1 |
| 11 | Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention 显示文摘 | Campo G Fileti L de Cesare N | 2010 | J Am College Cardiol2010，56，18： | 1 |
| 12 | Zinc inhibits the mixed lymphocyte culture显示文摘 | CAMPO C WELLINGHAUSEN N FABER C | | 0，，01： | 1 |
| 13 | Selection of models of lactation curves to use in milk production simulation systems显示文摘 | Cunha D N F V Pereira J C Campos O F | 2010 | Rev Bras Zootecn2010，39，4： | 1 |
| 14 | Chronic hepatitis induced by Jin Bu Huan显示文摘 | Picciotti A Campo N Brizzolara R | 1998 | Hepatol1998，28，： | 1 |
| 15 | Activity of maize transglutaminase overexpressed in Escherichia coli inclusion bodies:an alternative to protein refolding显示文摘 | Carvajal P Gibert J Campos N | | 0，，01： | 1 |
| 16 | Cytogenetic studies in peripheral blood of bovines afflicted by pap- illomatosis显示文摘 | Melo T C Diniz N Campos S R et ai | 2011 | Vet Comp Oncol2011，9，4： | 1 |
| 17 | Quaternary ammonium compounds: an alternative disinfection method for fresh produce wash water 显示文摘 | Chaidez C Lopez J Campo N C | 2007 | Journal of Water and Health2007，5，2： | 1 |
| 18 | Determination of sorbic acid in raw beef: An improved procedure显示文摘 | CAMPOS C GERSCHENSON L N ALZAMORA S M CHIRIFE J | 1991 | Food Sci1991，56，3： | 1 |
| 19 | Cloning and characterization of a gene from Escherichia coli encoding a transketolas-like enzyme that catalyzes the synthesis of 1-deoxy-D-xylulose-5- phosphate, a common precursor of isprenoid,thiamin,and pyridoxol biosynthesis显示文摘 | Lois L M Campos N Putra S R | 1998 | Proc Natl Acad Sci USA1998，95，： | 1 |
| 20 | Enhanced flux through the methylerythritol 4-phosphate pathway in Arobidopsis plants overexpressing , deoxyxylulose 5- phosphate reductoisomerase显示文摘 | CARRETERO-PAULET L CAIRO A BOTELLA-PAV:A P BE- SUMBES O CAMPOS N BORONAT A RODRfGUEZ-CONCEP- CIO M | 2006 | Plant Mol Biol2006，62，45： | 1 |
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