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| 1 | Community-Based User Domain Model Collaborative Recommendation Algorithm显示文摘Collaborative Filtering (CF) is a commonly used technique in recommendation systems. It can promote items of interest to a target user from a large selection of available items. It is divided into two broad classes: memory-based algorithms and model-based algorithms. The latter requires some time to build a model but recommends online items quickly, while the former is time-consuming but does not require pre-building time. Considering the shortcomings of the two types of algorithms, we propose a novel Community-based User domain Collaborative Recommendation Algorithm (CUCRA). The idea comes from the fact that recommendations are usually made by users with similar preferences. The first step is to build a user-user social network based on users' preference data. The second step is to find communities with similar user preferences using a community detective algorithm. Finally, items are recommended to users by applying collaborative filtering on communities. Because we recommend items to users in communities instead of to an entire social network, the method has perfect online performance. Applying this method to a collaborative tagging system, experimental results show that the recommendation accuracy of CUCRA is relatively good, and the online time-complexity reduces to O.n/. | Fulan Qian Yanping Zhang Yuan Zhang Zhen Duan | 2013 | Tsinghua Science and Technology2013，18，4： | 3 |
| 2 | The fourherb Chinese medicine PHY906 reduces chemotherapyinduced gastrointestinal toxicity 显示文摘 | Wing Lam Scott Bussom Fulan Guan | 2010 | Sci Transl Med2010，2，45： | 1 |
| 3 | Polymorphisms in genes of APE1 , PARP1 , and XRCC1 : risk and prognosis of colorectal cancer in a Northeast Chinese population显示文摘 | Ye Li Shuying Li Zhiwei Wu Fulan Hu Lin Zhu Xiaojuan Zhao Binbin Cui Xinshu Dong Suli Tian Fan Wang Yashuang Zhao | 2013 | Medical Oncology2013，，2： | 1 |
| 4 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 5 | Ultrasound-Guided High-Intensity Focused Ultrasound vs Laparoscopic Myomectomy for Symptomatic Uterine Myomas显示文摘 | Fulan Wang Liangdan Tang Li Wang Xiaoyan Wang Jinyun Chen Xiaohua Liu Yao Gong | 2014 | The Journal of Minimally Invasive Gynecology2014，，2： | 1 |
| 6 | Exploring pathogenesis in subjects with subjective Tinnitus having kidney deficiency pattern in terms of Traditional Chinese Medicine based on serum metabolic profiles显示文摘OBJECTIVE: To investigate the metabolic pathogenesis in subjects with subjective tinnitus(ST)having kidney deficiency pattern(KDP)(ST/KDP) in terms of Traditional Chinese Medicine.METHODS: Three groups of subjects, including healthy individuals, subjects with ST/KDP, and subjects who were healthy initially and then developed ST/KDP one year later(healthy → ST/KDP),were recruited for this study. Serum metabolic profiles of all subjects were analyzed using ultra-performance liquid chromatography coupled with quadruple-time-of-flight mass spectrometry. The metabolic characteristics of the ST/KDP subjects were determined, and the corresponding biomarkers were predicted. The metabolomics data from the healthy → ST/KDP subjects were collected for further verification.RESULTS: Twelve metabolites in the ST/KDP subjects were different from those of the healthy control subjects. Of these metabolites, according to the prediction, except for octanoic acid, other metabolites might characterize ST/KDP. Ten metabolites at the outcome ST/KDP stage were different from those at the initial(control) stage. Through the comparison of these metabolites with the predicted metabolites, five common metabolites, including upregulated glutamate, serotonin, oroticacid and 8-oxoguanine, as well as downregulated taurine, were found. These common metabolites were significantly associated with canonical pathways including calcium signaling, γ-aminobutyric acid(GABA) receptor signaling, purine and pyrimidine biosynthesis, taurine biosynthesis, and serotonin receptor signaling.CONCLUSION: The metabolic pathogenesis in ST/KDP subjects was characterized by upregulated glutamate, serotonin, orotic acid and 8-oxoguanine, as well as downregulated taurine, additionally, perturbations of calcium signaling, GABA receptor signaling, purine and pyrimidine biosynthesis, taurine biosynthesis, and serotonin receptor signaling. | Tan Yong Shen Shanshan Guan Fulan He Bing Lu Cheng Xiao Cheng Jiang Miao Zhao Ning Li Li Cheng Shiping Zu Xianpeng Zhang Weidong Liu Xinru Lü Aiping | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 1 |
| 7 | The prognostic significance of polymorphisms in hMLH1/hMSH2 for colorectal cancer显示文摘 | Yibaina Wang Guangxiao Li Fulan Hu Haoran Bi Zhiwei Wu Xiaojuan Zhao Ye Li Shuying Li Dandan Li Binbin Cui Xinshu Dong Yashuang Zhao | 2014 | Medical Oncology2014，，6： | 1 |
| 8 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 9 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 10 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 11 | Prevalence and associated factors of knee osteoarthritis in a community-based population in Heilongjiang, Northeast China显示文摘 | Liying Jiang Jiesheng Rong Qiuju Zhang Fulan Hu Shide Zhang Xia Li Yashuang Zhao Tianzun Tao | 2012 | Rheumatology International2012，，5： | 1 |
| 12 | APC alterations are frequently involved in the pathogenesis of acinar cell carcinoma of the pancreas, mainly through gene loss and promoter hypermethylation显示文摘 | Fulan D Sahnane N Bernasconi B | 2014 | Virchows Arch2014，464，5： | 1 |
| 13 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
| 14 | Can Vascular Endothelial Growth Factor and Microvessel Density Be Used as Prognostic Biomarkers for Colorectal Cancer? A Systematic Review and Meta-Analysis显示文摘 | Yibaina Wang Xiaoping Yao Jie Ge Fulan Hu Yashuang Zhao E. Z. Dajani C. Tosetti | 2014 | The Scientific World Journal2014，，： | 1 |
| 15 | APC altera tions are frequently involved in the pathogenesis of aci- nar cell carcinoma of the pancreas, mainly through gene loss and promoter hypermethylation 显示文摘 | Fulan D Sahnane N Bernasconi B | 2014 | Virchows Arch2014，464，5： | 1 |
| 16 | Current status of brain hydrolysate显示文摘 | Zhong Yuxu Li Fulan Zou Lijia | 1996 | Chin J Biochem Pharm1996，17，4： | 1 |
| 17 | Modeling transport of arsenic through modified granular natural siderite filters for arsenic removal显示文摘Groundwater arsenic (As) contamination is a hot issue,which is severe health concern worldwide.Recently,many Fe-based adsorbents have been used for As removal from solutions.Modified granular natural siderite (MGNS),a special hybrid Fe(II)/Fe(III) system,had higher adsorption capacity for As(III) than As(V),but the feasibility of its application in treating high-As groundwater is still unclear.In combination with transport modeling,laboratory column studies and field pilot tests were performed to reveal both mechanisms and factors controlling As removal by MGNS-filled filters.Results show that weakly acid pH and discontinuous treatment enhanced As(III) removal,with a throughput of 8700 bed volumes (BV) of 1.0 mg/L As(III) water at breakthrough of 10 mg/L As at pH 6.Influent HCO3^- inhibited As removal by the filters.Iron mineral species,SEM and XRD patterns of As-loading MGNS show that the important process contributing to high As(III) removal was the mineral transformation from siderite to goethite in the filter.The homogeneous surface diffusion modeling (HSDM) shows that competition between As(III) and HCO3^- with adsorption sites on MGNS was negligible.The inhibition of HCO3^- on As(III) removal was connected to inhibition of siderite dissolution and mineral transformation.Arsenic loadings were lower in field pilot tests than those in the laboratory experiments,showing that high concentrations of coexisting anions (especially HCO3^-- and SiO4^4-),high pH,low EBCT,and low groundwater temperature decreased As removal.It was suggested that acidification and aeration of high- As groundwater and discontinuous treatment would improve the MGNS filter performance of As removal from real high-As groundwater. | Fulan Li Huaming Guo Kai Zhao Wei Xiu Jiaxing Shen Yi Chen | 2019 | Geoscience Frontiers2019，10，5： | 1 |
| 18 | Mesenchymal stem cells derived from inflamed periodontal ligaments exhibit impaired immunomodulation显示文摘 | Dayong Liu Junji Xu Ousheng Liu Zhipeng Fan Yi Liu Fu Wang Gang Ding Fulan Wei Chunmei Zhang Songlin Wang | 2012 | J Clin Periodontol2012，，12： | 1 |
| 19 | Digital subtraction angiography in the evaluation of cerebrovascular disease显示文摘 | Fulan A J Weinstein M A Little J R | 1983 | J Neurol Clin1983，1，1： | 1 |
| 20 | Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery显示文摘 | Yao Qin Huali Chen Wenmin Yuan Rui Kuai Qianyu Zhang Fulan Xie Li Zhang Zhirong Zhang Ji Liu Qin He | 2011 | International Journal of Pharmaceutics2011，，1： | 1 |
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