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| 1 | bFGF and TGFβ expression in rat kidneys after ischemic/reperfusional gut injury and its relationship with tissue repair显示文摘INTRODUCTION Intestinal isehemia/rePerfusion(I/R)oeeureommonly in eritieally 111 Patients.It 15 wellreeognized that gutl/R may eause tissue damageand dysfunetion of intestine,and induee | Yang YH Fu XB Sun TZ Jiang LX Gu XM | 2000 | World Journal of Gastroenterology2000，6，1： | 13 |
| 2 | Clinical significance and pathogenic role of anti-cardiac myosin autoantibody in dilated cardiomyopathy显示文摘In order to explore the possible roles played by the autoimmune mechanism in the progression of myocarditis into dilated cardiomyopathy (DCM) using an animal model, we investigated whether autoimmune myocarditis might develop into DCM Methods Experimental Balb/C mice (n=20) were immunized with cardiac myosin with Freun d’s complete adjuvant at days 0, 7 and 30 The control Balb/C mice (n=10) were immunized with Freund’s complete adjuvant in the same mannere Serum and my ocardium samples were collected after the first immunization at days 15, 21 and 120 The anti-myosin antibody was examined by enzyme-linked immunosorbent assay and immunoblotting Results Pathological findings demonstrated that there was myocardial necrosis or inflammatory infiltration during acute stages and fibrosis mainly in the late phase of experimental group, but the myocardial lesions were not found in the control group Autoimmunity could induce myocarditis and DCM in the absence of viral infection High titer anti-myosin IgG antibodies were found in the experimental group, but not in the control group Furthermore, the anti-myosin heavy chain (200 KD) antibody was positive in 21 of 48 patients with DCM and viral myocarditis, but only 4 of 20 patients with coronary heart disease, including 1 case and 3 c ases that reacted with heavy and light chains (27 5 KD), respectively The antibodies were not detected in healthy donors Conclusion Cardiac myosin might be an autoantigen that provokes autoimmunity and leads to the transformation of myocarditis into DCM Detection of anti-myosin heavy chain antibody might contribute to diagnosis for DCM and viral | 汪朝晖 廖玉华 董继华 李淑莉 王金平 Michael LX Fu | 2003 | Chinese Medical Journal2003，，4： | 8 |
| 3 | Localization of a functional autoimmune epitope on the muscarinic acetycholine receptor-2 in patients with idiopathic dilated cardiomyopathy显示文摘 | Fu LX Magnusson Y Bergh CH | 1993 | J Clin Invest1993，91，5： | 1 |
| 4 | Cytotoxic constituents from Sola-num lyratum显示文摘 | Sun LX Fu WW Ren J | 2006 | Arch Pharm Res2006，29，2： | 1 |
| 5 | Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in-patients with idiopathic dilated cardiopathy显示文摘 | Magnusson Y Bergh C | 1993 | J Clin Invest1993，91，5： | 1 |
| 6 | Responses of antioxidant gene,protein and enzymes to salinity stress in two genotypes of perennial ryegrass (Lolium perenne) differing in salt tolerance显示文摘 | Hu LX Li HY Pang HC Fu JM | | 0，，02： | 1 |
| 7 | Design,synthesis,and biological evaluation of new 2’-deoxy-2’-fluoro-4’-triazole cytidine nucleosides as potent antiviral agents显示文摘 | Wu J Yu WQ Fu LX | 2013 | Eur J Med Chem2013，63，： | 1 |
| 8 | Nematodes as indicators of soil recovery in tailings of a lead/zinc mine 显示文摘 | Shao YH Zhang WX Shen JC Zhou LX Xia HP Shu WS Ferris H Fu SL | 2008 | Soil Biol Biochem2008，40，： | 1 |
| 9 | Preparation of curcumin loaded poly (3-capwlactone)-poly (ethylene glycol)-poly (3-caprolactone)nanofibers and their in vitro antitumor activity against Glioma 9L cells显示文摘 | Guo G Fu SZ Zhou LX | | 0，，9： | 1 |
| 10 | Partitioning soil respiration of subtropical forests with different successional stages in south China 显示文摘 | Yi ZG Fu SL Yi WM Zhou GY Mo JM Zhang DQ Ding MM Wang XM Zhou LX | 2007 | For Ecol Manage2007，243，2： | 1 |
| 11 | Localization of a functio n al antoimmune epitope on the muscarinic acetycholine receptor-2 in patients wit h idiopathic dilated cardiomyopathy显示文摘 | Yvonne Magnusson Claes-Hakan Bergh | 1993 | J Clin Invest1993，91，： | 1 |
| 12 | JK(a-b - ) and Kidd blood group genotypes in Chinese people显示文摘 | Yan LX Zhu FM Fu QH | 2003 | Transfusion2003，43，2： | 1 |
| 13 | Dilated cardiomyopat hy deffines serum autoantibodies against G-protein-coupled cardiovascular rece ptors显示文摘 | Michael LX Fu Masami Shimizu | 1995 | Autoimmunity1995，21，： | 1 |
| 14 | Ultrasensitive eolorimetrie detection of heparin based on self-assembly of gold nanoparticles on graphene oxide显示文摘 | Fu XL Chert LX Li JH | 2012 | Analyst2012，137，16： | 1 |
| 15 | Anti-M2-muscarinic receptor autoantibodies and idiopathic dilated cardiomyopathy显示文摘 | Fu LX | 1996 | Int J Cardiol1996，54，： | 1 |
| 16 | Localization of a functional autoimmune epitope on the muscarnic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy显示文摘 | Fu LX Yvonne M Claes-Makan B | 1993 | J Clin Invest1993，9，： | 1 |
| 17 | Vertical and horizontal profiles of airborne particulate matter near ma- jor roads in Macao, China 显示文摘 | WuY HaoJ M Fu LX | 2002 | Atmospheric Environment2002，36，31： | 1 |
| 18 | Localization of a functional autoimmune epitomes on the muscarinic acetylcholin receptor - 2 in patients with idiopathic dilated cardiomyopathy显示文摘 | Fu LX Magnusson Y Bergh C | 1993 | J Clin Invest1993，91，： | 1 |
| 19 | Dilated cardiomyopathy defines serum autoantibodies against G-protein coupled cardiovascular receptors显示文摘 | Matsui S Fu LX Shimizu M | 1995 | Immunol1995，21，： | 1 |
| 20 | Cytotoxic constituents from solanum lyratum显示文摘 | Sun LX Fu WW Ren J | 2006 | Arch Pharm Res2006，29，2： | 1 |
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