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| 1 | Isolation and characterization of bipotent liver progenitor cells from adult mouse显示文摘 | Li WL Su J Yao YC Tao XR Yan YB Yu HY Wang XM Li JX Yang YJ Lau JT HuYP | 2006 | 中国生物学文摘2006，20，5： | 26 |
| 2 | 门静脉高压并非肝细胞癌肝切除术的绝对禁忌证显示文摘在肝细胞癌(hepatocellular carcinoma,HCC)的各种临床分期系统中,Bruix J团队领衔的巴塞罗那肝癌临床分期标准(Barcelona Clinic Liver Cancer,BCLC)最受推崇,美国和欧洲肝病协会指南的制定亦基于该分期系统。BCLC认为门静脉高压显著增加HCC肝切除术后患者发生肝功能衰竭的风险, | Zhong JH Li H Xiao N Ye XP Ke Y Wang YY Ma L Chen J You XM Zhang ZY Lu SD Li LQ 钟鉴宏 齐鲁楠 | 2014 | 中国癌症防治杂志2014，6，4： | 18 |
| 3 | Antifungal activities and action mechanisms of compounds from Tribulus terrestris L.显示文摘 | Zhang JD Xu Z Cao YB Chen HS Yan L An MM Gao PH Wang Y Jia XM Jiang YY | 2006 | 第二军医大学学报2006，27，5： | 14 |
| 4 | Doxycycline-regulated co-expression of GDNF and TH in PC12 cells.显示文摘 | Wang JJ Zhang T Niu DB Wang K Li KR Xue B Wang XM | 2006 | 中国生物学文摘2006，20，10： | 11 |
| 5 | Effects of HBV gene variations on disease development and antiviral therapy for patients with chronic hepatitis B显示文摘Viral variation may change pathogenicity, escape immunity, lead to persistence infection, and cause drug resistance against antiviral therapy. This study was undertaken to investigate the effects of HBV gene variation on the progression of disease and on the efficacy of antiviral therapy for patients with chronic hepatitis B(CHB). METHODS:Hepatitis B virus (HBV) gene mutational sites were detected using gene chip in selected hepatitis B patients. RESULTS:In the patients HBeAg did not show serologic conversion or HBeAg(-)/anti-HBe(+), but their HBV DNA remained positive 24 weeks after α-interferon therapy, which was associated with mutations of nt1896, nt1814, nt1762 and nt1764. In the patients, that HBV DNA levels decreased or were undetectable, but rebounded later after antiviral therapy by lamivudine was associated with mutations of aa528 and(or) aa552(i.e.YMDD mutation), which resulted in lamivudine-resistance. YMDD mutation was prone to occur 52 weeks after lamivudine therapy in some chronic hepatitis B patients (26.4%). Nt1896 mutation was common in most chronic hepatitis B patients (68.5%). Chronic severe hepatitis, cirrhosis, and primary liver carcinoma were related to the mutations of nt1896, nt1762 and nt1764. CONCLUSIONS:HBV gene mutations could aggravate patient’s condition and affect the efficacy of antiviral therapy. The regular detection of HBV gene mutation is helpful for identification of disease prognosis and adjustment of therapeutic strategy. | Shenzhen Eastlake Hospital, Shenzhen 518020, China (Chen JY) and National Key Laboratory of Virology (Wuhan University) Department of Infectious Diseases, Renmin Hospital, Wuhan University, Wuhan 430060, China(Wang LW, Sun XM and Gong ZJ) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 8 |
| 6 | Comparison of gene expression between normalcolon mucosa and colon carcinoma by means of messenger RNA differential display显示文摘 | Wang L Lu W Chen YG Zhou XM Gu JR | 1999 | World Journal of Gastroenterology1999，5，6： | 4 |
| 7 | Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘 | Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX | 2006 | 中国生物学文摘2006，20，4： | 2 |
| 8 | THE VARIATIONAL PRINCIPLES FOR PYROELECTRIC MEDIA显示文摘The pyroelectric medium is an important material in the application of smart materialsand structures.It is necessary to systematically discuss all kinds of variational principles which play avery significant role in the fundamental theory of mechanics and numerical analysis method.This paperfirstly gives the quasi-static and the dynamic variational principles,then the principles for eigen prob-lems.As a simple example,the principle was finally applied to derive the fundamental equations for ananisotropic piezoelectric plate. | Wang, XM Shen, YP | 1995 | Acta Mechanica Solida Sinica1995，8，4： | 2 |
| 9 | Expression of heavy-chain variable domain of mAb against Encephalitis Type B virus in transgenic tobacco显示文摘SINCE the first report on immunoglobulin gene expression in plant by Hiatt et al. in 1989,analogous researches have been further developed. Up to now, it has become a new method touse transgenic plants and plant cells to produce antibodies and study disease-resistance breedingof crops, plant metabolism and growth, which is an organic combination of immunologyand plant sciences at molecular level. According to recent reports, both higher and lowerplants, such as tobacco, Arabidopsis, calli of maize and unicellular green alga, can | Wu, YQ Xiong, XM Zeng, JZ Zhang, J Wang, DJ Huang, HL | 1997 | Chinese Science Bulletin1997，42，12： | 2 |
| 10 | Spatial variation regularities of cosmic radiation and evaluation of exposure doses to aircrews显示文摘 | Gui SG Fan XM | 1996 | Chin J Radiol Med Prot1996，16，6： | 1 |
| 11 | Experimental study of cardiac muscle tissue engineering in bioreactor显示文摘 | Liu X Wang CY Guo XM | 2003 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao2003，25，1： | 1 |
| 12 | The involvement of glycogen synthase kinase-3 and PP-2A in lactacystin-induced tau accumulation 显示文摘 | Ren QG Liao XM Wang ZF | 2006 | FEBS Lett2006，550，10： | 1 |
| 13 | Phosphorylation/dehhosphorylation of an- drogen receptor as a determinant of androgen agonistic or antagonistic activity显示文摘 | Wang LG Liu XM Kreis W | 1999 | Bioehem Biophys Res Commun1999，259，： | 1 |
| 14 | Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung显示文摘 | Chen YH Wang PP Wang XM | 2011 | Cytokine2011，53，3： | 1 |
| 15 | Analgesic activity of myricetin isolated from Myrica rubra Sieb et Zucc Leaves 显示文摘 | TONG Y ZHOU XM WANG SJ | 2009 | Archives of Pharmacal Research2009，32，4： | 1 |
| 16 | Relationship between cardiovascular function and fetal growth restriction in women with pre-eclampsia显示文摘 | Jia RZ Liu XM Wang X | 2010 | Int J Gynaecol Obstet2010，110，1： | 1 |
| 17 | Carbon coated superpara- magnetic iron oxide nanoparticles for sentinel lymph nodes mapping 显示文摘 | Wang YX Wang DW Zhu XM | 2012 | Quant Imaging Med Surg2012，2，1： | 1 |
| 18 | Adenovirus mediated hemeoxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells 显示文摘 | Liu XM Chapman GB Wang H | 2002 | Circulation2002，105，1： | 1 |
| 19 | B7-H4 is preferentially expressed in non-dividing brain tumor ceils and in a subset of brain tumor stem-like cells显示文摘 | Yao Y Wang XM Jin KL | 2008 | J Neurooncol2008，89，2： | 1 |
| 20 | Metabolic network properties help assign weights to elementary modes to understand physiological flux distributions显示文摘 | Wang, QZ Yang, YD Ma, HW Zhao, XM | 2007 | 中国生物学文摘2007，21，10： | 1 |
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