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| 1 | SPSBl-mediated HnRNP A1 alternative splicing and cell ubiquitylation regulates migration in EGF signaling显示文摘细胞外的信号被显示了影响拼接的其他的 pre-mRNA;然而,分子的机制和导致信号的拼接的规定的生物意义仍然保持大部分未知。这里,我们报导那个表皮的生长因素(EGF ) 通过一个著名拼接管理者的 ubiquitylation 导致拼接的变化, hnRNP A1。EGF 发信号 upregulates 一个 E3 ubiquitin (Ub ) ligase 适配器,敏捷的包含域的 SOCS 盒子蛋白质 1 (SPSB1 ) ,它结合离氨酸 29 连接 polyUb 链到 hnRNP A1 上的成员 Elongin B/C-Cullin 建筑群。重要地, hnRNP A1 的 SPSB1 和 ubiquitylation 在驾驶 EGF 的房间移植有一个关键角色。机械学地,和 SR 蛋白质 kinases (SRPK ) 的激活的 hnRNP A1 的导致 EGF 的 ubiquitylation 导致拼接的 Rac1 的 upregulation isoform, Rac1b,支持房间活动性。这些调查结果解开在蛋白质 ubiquitylation 并且在 EGF/EGF 受体发信号的其他的拼接之间的新奇串音,并且在 modulating 房间移植识别新 EGF/SPSB1/hnRNP A1/Rac1 轴,它可以为癌症治疗有重要含意。 | Feng Wang Xing Fu Peng Chen Ping Wu Xiaojuan Fan Na Li Hong Zhu Ting-Ting Jia Hongbin Ji Zefeng Wang Catherine C L Wong Ronggui Hu Jingyi Hui | 2017 | Cell Research2017，27，4： | 5 |
| 2 | A novel XPF-357A 〉 C polymorphism predicts risk and recurrence of bladder cancer(摘要)显示文摘 | Wang, M Yuan, L Wu, D Zhang, Z Yin, C Fu, G Wei, Q | 2010 | 南京医科大学学报(自然科学版)2010，30，7： | 5 |
| 3 | Joint optimization for power loss reduction in distribution systems显示文摘 | Zhang D Fu Z C Zhang L C | 2008 | IEEE Trans on Power Systems2008，23，1： | 1 |
| 4 | Handle- aware isolines for scalable shape editing显示文摘 | Au O K C Fu H B Tai C L | 2007 | ACM Transactions on Graphics2007，26，3： | 1 |
| 5 | Doping effects of magnesium onthe electrochemical performance of Li2FeSiO4 for lithium ion bat-teries显示文摘 | Zhang S Deng C Fu B L | 2010 | J Electroanal Chem2010，644，2： | 1 |
| 6 | A review on pharmacological activities and utilization technologies of pumpkin 显示文摘 | Fu C L Shi H Li Q H | 2006 | Plant foods for human nutrition2006，，61： | 1 |
| 7 | Supplementation-time dependence of growth factors in promoting tendon healing显示文摘 | Chan B P Fu S C Qin L | 2006 | Clin Orthop Relat Res2006，448，1： | 1 |
| 8 | Analyzing the applicability of Dempster's rule to the combination of interval-valued belief structures显示文摘 | Fu C Yang S L | | 0，，04： | 1 |
| 9 | Characterization of Li2MnSiO4 and Li2FeSiO4 cathode materials synthesized via a citric acid assisted sol-gel method显示文摘 | Deng C Zhang S Fu B L | | 0，，01： | 1 |
| 10 | Isolation and functional characte- rization of JcFT, a FLOWERING LOCUS T (FF) homolog- ous gene from the biofuel plant Jatropha curcas显示文摘 | Li C Luo L Fu Q | 2014 | BMC Plant Biol2014，14，： | 1 |
| 11 | Responses of trophic groups of soil nematodes to residue application under conventional tillage and no- till regimes 显示文摘 | Fu S L Coleman D C Hendrix P F | 2000 | Soil Biology and Biochemistry2000，32，： | 1 |
| 12 | Heterotrimeric G proteins regulate nitrogen-use efficiency in rice 显示文摘 | Sun H Y Qian Q Wu K Luo J J Wang S S Zhang C W Ma Y F Liu Q Huang X Z Yuan Q B Han R X Zhao M Dong G J Guo L B Zhu X D Gou Z H Wang W Wu Y J Lin H X Fu X D | 2014 | Nature Genetics2014，46，4： | 1 |
| 13 | Robust adaptive decentralized control of robot manipulators显示文摘 | Fu L C | 1992 | IEEE Trans on Automatic Control1992，37，1： | 1 |
| 14 | Surface modifications of electrode materials for lithium ion batteries显示文摘 | FU L J LIU H LI C WU Y P RAHM E HOLZE R WU H Q | 2006 | Solid State Sci2006，8，2： | 1 |
| 15 | General Iteration Algorithms for Classification Ratemaking 显示文摘 | Fu L Wu C P | 2007 | Variance2007，1，2： | 1 |
| 16 | Control of a key transition from prostrate to erect growth in rice domestication显示文摘 | Tan L Li X Liu F Sun X Li C Zhu Z Fu Y Cat H Wang X Xie D Sun C | 2008 | Nature Genetics2008，40，11： | 1 |
| 17 | A review of surface erosion and sediment delivery models for unsealed roads 显示文摘 | Fu B Newham L T H Ramos-Scharron C E | 2010 | Environmental Modelling & Software2010，25，1： | 1 |
| 18 | The potential regulato- ry mechanisms of miR - 196a in huntington 's disease through bioinformatic analyses 显示文摘 | Fu M H Li C L Lin H L | 2015 | PLoS One2015，10，01： | 1 |
| 19 | Structural design of a carbon fiber-reinforced polymer wheel for ultra-high speed grinding 显示文摘 | YANG L FU Y C XU J H | 2015 | Materials and Design2015，88，： | 1 |
| 20 | Microstructure and dielectric properties of Bax-Sr1-xTiO3 ceramics 显示文摘 | Fu C L Yang C R Chen H W | 2005 | Mater Sci Eng B2005，119，2： | 1 |
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