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| 1 | Phosphorylation switch modulates the interdigitated pattern of PIN1 localization and cell expansion in Arabidopsis leaf epidermis显示文摘在多细胞的纸巾以内,房间可以并列地形成一单个或多重的极的轴,而是它是不清楚的普通机制是否管理极的轴形成的不同类型。大头针蛋白质的 phosphorylation 地位,被 PINOID (PID ) 蛋白质 kinase 和 PP2A 蛋白质磷酸酶直接影响,被知道在根和射击顶的双极的房间调整大头针本地化的顶端基础的极性。这里,我们提供证据 phosphorylation 调停地位的大头针极性开关广泛地被用来与交错的脑叶和缩进包括多极的人行道房间(PC ) 在 Arabidopsis 调制细胞的进程。当 FYPP1 基因,编码称为联系 phytochrome 的 serine/threonine 蛋白质磷酸酶的 PP2A,被击倒时或当 PID 基因是 overexpressed (35S::PID ) 时, PC interdigitation 的度也极大地被减少。这些基因修正引起了 PIN1 本地化从脑叶切换到缩进区域。PP2A 和 PID 调停了 PIN1 本地化切换惊人地类似于他们在另外的房间的大头针蛋白质的顶端基础的极性开关的规定。我们的调查结果为 PIN1 极性形成,在织物 / 器官两个都为模式形成是关键的一个基本细胞的过程和细胞的层次的规定建议普通机制。 | Hongjiang Li Deshu Lin Pankaj Dhonukshe Shingo Nagawa Dandan Chen Jifi Friml Ben Scheres Hongwei Guo Zhenbiao Yang | 2011 | Cell Research2011,21,6: | 7 |
| 2 | Cellular and Molecular Requirements for Polar PIN Targeting and Transcytosis in Plants显示文摘极,大头针植物生长素流出搬运人的亚 cellular 本地化决定细胞间的植物生长素流动的方向,因此定义植物生长素发信号的空间方面。动态,大头针蛋白质的象 transcytosis 一样本地化响应外部、内部的信号发生,在植物生长素分发把这些信号集成到变化。这里,我们检验极的大头针交货和 transcytosis 的细胞、分子的机制。机制 ARFGEF 依赖的极的指向和 transcytosis 很好在调整植物开发在与他们的基本重要性一致的多样的 Arabidopsis 生态型之中被保存并且出现小变化。在细胞的水平,我们在顶端、基础的大头针指向在肌动朊细胞骨架的角色上精制以前的调查结果,并且为微导管识别一个以前未知的角色,明确地在基础指向。到房间的不同方面的大头针蛋白质交货被 ARF 依赖的 trafficking 与不同 ARFGEF 泡 trafficking 管理者的以前未知的复杂水平调停。我们的数据建议由这些不同小径的大头针蛋白质的其他的招募能响应不同信号说明类型特定的房间和极的指向的货物特定的方面,以及为极性变化。结果动态大头针放到房间的不同方面在植物纸巾以内定义植物生长素流动的一个三维的模式。 | Jurgen Kleine-Vehn tukasz tangowski Justyna Wisniewska Pankaj Dhonukshe Philip B Brewer Jiri Friml | 2008 | Molecular Plant2008,1,6: | 5 |
| 3 | Osmotic Stress Modulates the Balance between Exocytosis and Clathrin-Mediated Endocytosis in Arabidopsis thaliana显示文摘植物的无柄的生活方式创造需要处理经常不利的环境,在水,可获得性能在一个每日的基础上变化,质问细胞的生理学和正直。处于渗透的条件的变化破坏血浆膜的平衡:hypoosmotic 条件 increaseand hyperosmotic 环境减少房间卷。这里,我们证明短期的细胞外的渗透的处理被移动仔细在根分裂组织房间处于在 endocytosis 和 exocytosis 之间的平衡跟随。尖锐 hyperosmotic 处理(离子并且 nonionic ) 同时提高调停 clathrin 的 endocytosis attenuating exocytosis,而 hypoosmotic 处理有相反的效果。除了到血浆膜的 clathrin 招募,早 endocytic trafficking 的部件在 hyperosmotic 压力回答期间是必要的。因而,在 clathrin 或早 endocytic 机械的元素有缺点的幼苗的生长对 hyperosmotic 处理更敏感。我们也发现对在环境的渗透的地位的一个变化的 endocytotic 反应在植物荷尔蒙的大概进化的更最近的规章的效果上是主导的,例如植物生长素。这些结果暗示那渗透的不安影响在通过调停 clathrin 的 endocytosis 行动的 endocytosis 和 exocytosis 之间的平衡。我们建议血浆膜上的那紧张在房间表面决定膜的增加或移动,因此保存房间正直。 | Marta Zwiewka Tomasz Nodzynski Stephanie Robert Steffen Vanneste Jiri Friml | 2015 | Molecular Plant2015,8,8: | 5 |
| 4 | Auxin signaling:Research advances over the past 30 years显示文摘Auxin,one of the first identified and most widely studied phytohormones,has been and will remain a hot topic in plant biology.After more than a century of passionate exploration,the mysteries of its synthesis,transport,signaling,and metabolism have largely been unlocked.Due to the rapid development of new technologies,new methods,and new genetic materials,the study of auxin has entered the fast lane over the past 30 years.Here,we highlight advances in understanding auxin signaling,including auxin perception,rapid auxin responses,TRANSPORT INHIBITOR RESPONSE 1 and AUXIN SIGNALING F-boxes(TIR1/AFBs)-mediated transcriptional and non-transcriptional branches,and the epigenetic regulation of auxin signaling.We also focus on feedback inhibition mechanisms that prevent the over-amplification of auxin signals.In addition,we cover the TRANSMEMBRANE KINASE-mediated non-canonical signaling,which converges with TIR1/AFBs-mediated transcriptional regulation to coordinate plant growth and development.The identification of additional auxin signaling components and their regulation will continue to open new avenues of research in this field,leading to an increasingly deeper,more comprehensive understanding of how auxin signals are interpreted at the cellular level to regulate plant growth and development. | Zipeng Yu Feng Zhang JiříFriml Zhaojun Ding | 2022 | Journal of Integrative Plant Biology2022,64,2: | 3 |
| 5 | The AP-3 adaptor complex is required for vacuolar function in Arabidopsis显示文摘Subcellular trafficking 在真核细胞的房间为大量的功能被要求。它包含货物排序,在多重层次的泡形成, trafficking 和熔化过程的规定。适配器蛋白质(AP ) 建筑群是货物在酵母和哺乳动物排序进泡的关键管理者,但是他们在植物的存在和功能没被表明。这里,我们报导影响蛋白质的 trafficking 的鉴定 4 (pat4 ) 在通常认为的 δ 的变异的有缺陷者;AP-3 建筑群的子单元。pat4 和 pat2,从缺乏功能的通常认为的 AP-3 β 的一样的 GFP 基于成像的向前基因的屏幕孤立的异种;,以及主导的否定 AP-3 μ难辨别的显型由大部分正常的形态学和开发描绘了的转基因的线显示,而是在异常 vacuolar 结构的膜蛋白质的强壮的细胞内部的累积。所有异种在形态学和功能是有缺点的 lysin 并且蛋白质存储液泡(PSV ) 但是储备蛋白质排序到 PSV 的表演正常。Immunoprecipitation 实验和基因研究揭示了通常认为的 AP-3 β 的紧密的功能、物理的协会;并且 AP-3 δ子单元。而且,两蛋白质仔细与通常认为的 AP-3 μ 被连接;并且 σ子单元和 clathrin 和 dynamin 机械的几个部件。一起拿,这些结果表明那 AP 建筑群,类似于那些在另外的优核质,在植物,和那 AP-3 存在在植物房间在生物的续生说的规定和液泡的功能起一个特定的作用。 | Marta Zwiewka Elena Feraru Barbara Moller Inhwan Hwang Mugurel I Feraru Jargen Kleine-Vehn Dolf Weijers Jifi Friml | 2011 | Cell Research2011,21,12: | 3 |
| 6 | Colonization of endophyte Acremonium sp. D212 in Panax notoginseng and rice mediated by auxin and jasmonic acid显示文摘Endophytic fungi can be beneficial to plant growth. However, the molecular mechanisms under-lying colonization of Acremonium spp. remain unclear. In this study, a novel endophytic Acremonium strain was isolated from the buds of Panax notoginseng and named Acremonium sp. D212. The Acremonium sp. D212 could colonize the roots of P. notoginseng, enhance the resistance of P. notoginseng to root rot disease, and promote root growth and saponin bio-synthesis in P. notoginseng. Acremonium sp. D212 could secrete indole-3-acetic acid (IAA) and jasmonic acid (JA), and inoculation with the fungus increased the endogenous levels of IAA and JA in P. noto-ginseng. Colonization of the Acremonium sp. D212 in the roots of the rice line Nipponbare was dependent on the concentration of methyl jasmonate (MeJA) (2–15μmol/L) and 1-naphthalenacetic acid (NAA) (10–20μmol/L). Moreover, the roots of the JA signaling-defective coi1-18 mutant were colonized by Acremonium sp. D212 to a lesser degree than those of the wild-type Nipponbare and miR393b-overexpressing lines, and the colonization was res-cued by MeJA but not by NAA. It suggests that the cross-talk between JA signaling and the auxin biosynthetic pathway plays a crucial role in the colonization of Acremonium sp. D212 in host plants. | Li Han Xuan Zhou Yiting Zhao Shusheng Zhu Lixia Wu Yunlu He Xiangrui Ping Xinqi Lu Wuying Huang Jie Qian Lina Zhang Xi Jiang Dan Zhu Chongyu Luo Saijie Li Qian Dong Qijing Fu Kaiyuan Deng Xin Wang Lei Wang Sheng Peng Jinsong Wu Weimin Li JiǐíFriml Youyong Zhu Xiahong He Yunlong Du | 2020 | Journal of Integrative Plant Biology2020,62,9: | 2 |
| 7 | Cytokinin signaling regulates pavement cell morphogenesis in Arabidopsis显示文摘难题有交错的脑叶的塑造片的 Arabidopsis 叶人行道房间(PC ) 并且缩排是一个好模型系统调查在纸巾以内协调房间极性和形状形成的机制。植物生长素被显示了 GTPase 依赖的发信号由激活 ROP 协调 interdigitation 小径。识别另外的部件或机制,我们与反常 PC 形态发生为异种屏蔽了并且发现细胞激动素发信号调整 PC interdigitation 模式。在细胞激动素累积的减小和在细胞激动素发信号的缺点(例如在 ARR7-over-expressing 线, ahk3cre1 细胞激动素受体异种,和 ahp12345 细胞激动素表明异种) 提高的 PC interdigitation,而细胞激动素的生产过剩和细胞激动素在一根 ARR20 在表示上线发信号的在激活上在整个子叶推迟了或废除 PC interdigitation。基因、生物化学的分析建议表明 ROP 在上游的行为压制交错的模式的形成的那细胞激动素。我们的结果提供控制 PC 形状的小径的新奇机械学的理解并且揭开为细胞激动素在房间形态发生发信号的一个新角色。 | Hongjiang Li Tongda Xu Deshu Lin Mingzhang Wen M ingtang Xie Jērōme Duclercq Agnieszka Bielach Jungmook Kim G Venugopala Reddy Jianru Zuo Eva Benková Jiгi Friml Hongwei Guoz Zhenbiao Yang | 2013 | Cell Research2013,23,2: | 2 |
| 8 | Control of leaf vascular patterning by polar auxin transport显示文摘 | Scarpella E Marcos D Friml J | 2006 | Genes Dev2006,20,: | 1 |
| 9 | Adaptor Protein Complex 2–Mediated Endocytosis Is Crucial for Male Reproductive Organ Development in Arabidopsis[W]显示文摘 | Soo Youn Kim Zheng-Yi Xu Kyungyoung Song Dae Heon Kim Hyangju Kang Ilka Reichardt Eun Ju Sohn Ji?í Friml Gerd Juergens Inhwan Hwang | 2013 | The Plant Cell2013,,8: | 1 |
| 10 | Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis 显示文摘 | Friml J Vieten A Sauer M Weijers D Schwarz H Hamann T Offringa R Jurgens G | 2003 | Nature2003,426,: | 1 |
| 11 | The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo显示文摘 | NAWY T BAYER M MRAVEC J FRIML J BIRNBAUM K D LUKOWITZ W | 2010 | Developmental Cell2010,19,: | 1 |
| 12 | Clathrin-mediated endocytosis: the gateway into plant cells显示文摘 | Xu Chen Niloufer G Irani Ji?í Friml | 2011 | Current Opinion in Plant Biology2011,,6: | 1 |
| 13 | Lateral relocation of auxin effltux regulator PIN3 mediates tropism in Arabidopsis显示文摘 | FRIML J WISNIEWSKA J | 2002 | Nature2002,,415: | 1 |
| 14 | Clathrin-Mediated Constitutive Endocytosis of PIN Auxin Efflux Carriers in Arabidopsis显示文摘 | Pankaj Dhonukshe Fernando Aniento Inhwan Hwang David G. Robinson Jozef Mravec York-Dieter Stierhof Ji?í Friml | 2007 | Current Biology2007,,6: | 1 |
| 15 | Molecular and cellular aspects of auxin-transport-mediated development显示文摘 | Vieten A Sauer M Brewer P B Friml J | 2007 | Trends in Plant Science2007,12,4: | 1 |
| 16 | Auxin transport-shaping the plant显示文摘 | FRIML J | 2003 | Current Opinion in Plant Biology2003,6,1: | 1 |
| 17 | Polar PIN localization directs auxin flow in plants显示文摘 | Wisniewska J Xu J Seifertová D Brewer P B Ruzicka K Blilou I Rouquiē D Benková E Scheres B Friml J | 2006 | Science2006,312,883: | 1 |
| 18 | Apical -basal polarity:why plant cells don't standon their heads显示文摘 | FRIML J BENFEY P BENKOV E | 2006 | Trends in Plant Science2006,11,1: | 1 |
| 19 | PIN-dependent auxin transport Action, regulation, and evolution显示文摘 | Adamowski M Friml J | 2015 | Plant Cell2015,27,1: | 1 |
| 20 | Competitive canalization of PIN-dependent auxin flow from axillary buds controls pea bud outgrowth显示文摘 | Balla J Kalousek P Reinohl V Friml J Procházka S | 2011 | Plant Journal2011,65,4: | 1 |