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| 1 | Colonization of endophyte Acremonium sp. D212 in Panax notoginseng and rice mediated by auxin and jasmonic acid显示文摘Endophytic fungi can be beneficial to plant growth. However, the molecular mechanisms under-lying colonization of Acremonium spp. remain unclear. In this study, a novel endophytic Acremonium strain was isolated from the buds of Panax notoginseng and named Acremonium sp. D212. The Acremonium sp. D212 could colonize the roots of P. notoginseng, enhance the resistance of P. notoginseng to root rot disease, and promote root growth and saponin bio-synthesis in P. notoginseng. Acremonium sp. D212 could secrete indole-3-acetic acid (IAA) and jasmonic acid (JA), and inoculation with the fungus increased the endogenous levels of IAA and JA in P. noto-ginseng. Colonization of the Acremonium sp. D212 in the roots of the rice line Nipponbare was dependent on the concentration of methyl jasmonate (MeJA) (2–15μmol/L) and 1-naphthalenacetic acid (NAA) (10–20μmol/L). Moreover, the roots of the JA signaling-defective coi1-18 mutant were colonized by Acremonium sp. D212 to a lesser degree than those of the wild-type Nipponbare and miR393b-overexpressing lines, and the colonization was res-cued by MeJA but not by NAA. It suggests that the cross-talk between JA signaling and the auxin biosynthetic pathway plays a crucial role in the colonization of Acremonium sp. D212 in host plants. | Li Han Xuan Zhou Yiting Zhao Shusheng Zhu Lixia Wu Yunlu He Xiangrui Ping Xinqi Lu Wuying Huang Jie Qian Lina Zhang Xi Jiang Dan Zhu Chongyu Luo Saijie Li Qian Dong Qijing Fu Kaiyuan Deng Xin Wang Lei Wang Sheng Peng Jinsong Wu Weimin Li JiǐíFriml Youyong Zhu Xiahong He Yunlong Du | 2020 | Journal of Integrative Plant Biology2020，62，9： | 2 |
| 2 | Experimental Study on Improvement Effects of Completely Weathered Phyllite Using Red Clay and Cement for High-Speed Railway Embankments显示文摘Completely weathered phyllite(CWP)has the characteristics of difficult compaction,low shear strength after compaction and large settlement after construction.The traditional improvement method using a single agent of red clay or cement for CWP satisfies the subgrade requirements for ordinary railway,but cannot meet the requirements of immediate strength and long-term post-construction settlement of high-speed railway at the same time.A series of experimental investigations were undertaken for the blended CWP soils,with three additives used.The first additive was red clay,the second was cement and the third was a combination of both red clay and cement at various portions.Results of consolidation test and shear strength test carried out for the treated CWP soils show that:1)The effect of cement on improving the compression modulus of CWP is much better than that of red clay;2)The settlement of an embankment of 10 m high formed by blended soil of CWP with 3%cement can be controlled within 15 mm,while the settlement will be 25.15 mm for the same embankment of blended soil of CWP with 40%red clay;3)The shear strength and ultimate bearing capacity of CWP improved by red clay are much better than those of 5%cement;4)The ultimate bearing capacity of CWP improved by 40%red clay is 3.42 times of that by 3%cement and 2.95 times by 5%cement.Furthermore,the bearing capacity of CWP when improved by red clay can meet railway subgrade requirements immediately after compaction,while cement improved CWP needs a curing time of 1 day or longer.This is an impediment to rapid construction process.The improvement mechanism of red clay is mainly filling effect and grading improvement effect,while the improvement mechanism of cement is mainly hardening reaction,which produces high strength material to cement.It is found that 40%red clay and 3%cement treated CWP,which is considered to be optimum,can meet the subgrade requirements of both immediate bearing capacity and long-term post-construction settlement for the high-speed railway. | Xiushao Zhao Jianglong Rao Qijing Yang Yu Rong Zhitao Fu Zhiyao Wang Zixi Chen | 2022 | Journal of Renewable Materials2022，10，5： | 1 |
| 3 | Halogen modified two-dimensional covalent triazine frameworks as visible-light driven photocatalysts for overall water splitting显示文摘The covalent triazine framework CTF-1 as a member of the two-dimensional covalent organic frameworks(COFs)is a category of novel metal-free photocatalysts for water splitting.The large band gap severely restricts its energy conversion efficiency.By means of the first-principles calculations,we proposed the decoration of CTF-1 by anchoring halogen atoms onto benzene moieties for improving the solar-to-hydrogen(STH)efficiency.The electronic structures reveal that the halogen substitution successfully decreases the band gap of CTF-1.Meanwhile,the calculated free energy changes along the reaction pathway indicate that all these COFs can spontaneously drive overall water splitting under light irradiation in a specific acid-base environment.The time-dependent ab initio non-adiabatic molecular dynamics simulations suggest that the electron-hole recombination periods of these COFs fall in a few to tens of nanoseconds.Excitingly,CTF-1 modified by linking six iodine atoms onto the benzene ring in the para-position(CTF-1-6I)shows a quite low band gap of 2.81 eV,indicating that it is a visible-light driven COF for overall photocatalytic water splitting.Correspondingly,CTF-1-6I also exhibits an extraordinarily promising STH efficiency of 3.70%,which is an order magnitude higher than that of the pristine CTF-1. | Cen-Feng Fu Chuanyu Zhao Qijing Zheng Xingxing Li Jin Zhao Jinlong Yang | 2020 | Science China Chemistry2020，63，8： | 1 |
| 4 | The S100 calcium binding protein A11 promotes liver fibrogenesis by targeting TGF-βsignaling显示文摘Liver fibrosis is a key transformation stage and also a reversible pathological process in various types of chronic liver diseases.However,the pathogenesis of liver fibrosis still remains elusive.Here,we report that the calcium binding protein A11(S100A11)is consistently upregulated in the integrated data from GSE liver fibrosis and tree shrew liver proteomics.S100A11 is also experimentally activated in liver fibrosis in mouse,rat,tree shrew,and human with liver fibrosis.While overexpression of S100A11 in vivo and in vitro exacerbates liver fibrosis,the inhibition of S100A11 improves liver fibrosis.Mechanistically,S100A11 activates hepatic stellate cells(HSCs)and the fibrogenesis process via the regulation of the deacetylation of Smad3 in the TGF-βsignaling pathway.S100A11 physically interacts with SIRT6,a deacetylase of Smad2/3,which may competitively inhibit the interaction between SIRT6 and Smad2/3.The subsequent release and activation of Smad2/3 promote the activation of HSCs and fibrogenesis.Additionally,a significant elevation of S100A11 in serum is observed in clinical patients.Our study uncovers S100A11 as a novel profibrogenic factor in liver fibrosis,which may represent both a potential biomarker and a promising therapy target for treating liver fibrosis and fibrosis-related liver diseases. | Tingting Zhu Linqiang Zhang Chengbin Li Xiaoqiong Tan Jing Liu Huiqin Li Qijing Fan Zhiguo Zhang Mingfeng Zhan Lin Fu Jinbo Luo Jiawei Geng Yingjie Wu Xiaoju Zou Bin Liang | 2022 | Journal of Genetics and Genomics2022，49，4： | 0 |
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