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| 1 | Liver hemangioma and vascular liver diseases in patients with systemic lupus erythematosus显示文摘AIM:To investigate whether systemic lupus erythematosus (SLE) is associated with benign focal liver lesions and vascular liver diseases, since these have been occasionally reported in SLE patients. METHODS:Thirty-five consecutive adult patients with SLE and 35 age-and sex-matched healthy controls were evaluated. Hepatic and portal vein patency and presence of focal liver lesions were studied by colour-Doppler ultrasound, computerized tomography and magnetic resonance were used to refine the diagnosis, clinical data of SLE patients were reviewed. RESULTS:Benign hepatic lesions were common in SLE patients (54% vs 14% controls, P < 0.0001), withhemangioma being the most commonly observed lesion in the two groups. SLE was associated with the presence of single hemangioma [odds ratios (OR) 5.05; 95% confidence interval (CI) 1.91-13.38] and multiple hemangiomas (OR 4.13; 95% CI 1.03-16.55). Multiple hemangiomas were associated with a longer duration of SLE (9.9 ± 6.5 vs 5.5 ± 6.4 years; P = 0.04). Imaging prior to SLE onset was available in 9 patients with SLE and hemangioma, showing absence of lesions in 7/9. The clinical data of our patients suggest that SLE pos- sibly plays a role in the development of hemangioma. In addition, a Budd-Chiari syndrome associated with nodular regenerative hyperplasia (NRH), and a NRH associated with hepatic hemangioma were observed, both in patients hospitalized for abdominal symptoms, suggesting that vascular liver diseases should be specifically investigated in this population. CONCLUSION:SLE is associated with 5-fold increased odds of liver hemangiomas, suggesting that these might be considered among the hepatic manifestations of SLE. | Annalisa Berzigotti Marilena Frigato Elena Manfredini Lucia Pierpaoli Rita Mulè Carolina Tiani Paola Zappoli Donatella Magalotti Nazzarena Malavolta Marco Zoli | 2011 | World Journal of Gastroenterology2011，17，40： | 5 |
| 2 | The stability of hepatitis C virus RNA after storage at +4 degrees C显示文摘 | Gessoni G Barin P Frigato A | | 0，，： | 1 |
| 3 | Effects of cilazapril and amlodipin on kidney function in hypertensive NIDDM patients显示文摘 | Velussi M Brocco E Frigato F | 1996 | Diabetes1996，45，3： | 1 |
| 4 | Quantitative ultrasound assessment of bone显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
| 5 | Hypothermia modulates circadian clock gene expression in lizard peripheral tissues显示文摘 | Vallone D Frigato E Vernesi C | 2007 | Am J Physiol Regul Integr Comp Physiol2007，292，1： | 1 |
| 6 | The stability of hepatitis C virus RNA after storage at +4 degrees C 显示文摘 | Barin P Frigato A | 2000 | J Viral Hepat2000，7，4： | 1 |
| 7 | Quantitative ultrasound assessment of bone显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
| 8 | Effects of Exercise Training on Endothelial Progenitor Cells in Patients With Chronic Heart Failure显示文摘 | Patrizio Sarto Elena Balducci Giovanna Balconi Fabio Fiordaliso Laura Merlo Giancarlo Tuzzato Giovanni L. Pappagallo Nicoletta Frigato Albino Zanocco Concetta Forestieri Giuseppe Azzarello Antonio Mazzucco Maria Teresa Valenti Flora Alborino Donatella Nov | 2007 | Journal of Cardiac Failure2007，，9： | 1 |
| 9 | The relationship ofvitamin D status to bone mineral density in an Italian population of postmenopausal women显示文摘 | Malavolta N Pratelli L Frigato M | 2005 | Osteoporos Int2005，16，： | 1 |
| 10 | Quantitative ultrasound assessment of bone显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
| 11 | Quantitative uhrasound assess- ment of bone 显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
| 12 | Effects of cilazpril and am-lodipin on kidney function hypertensive NIPM patients显示文摘 | Brocco E Frigato F | 1996 | Diabetes1996，45，4： | 1 |
| 13 | Effects of cilazpril and amlodipine on kidney function in hypertensive NIDDM patients显示文摘 | Velussi M Brocco E Frigato F | 1996 | Diabetes1996，45，3： | 1 |
| 14 | Circadian variation of cell proliferation in HTR 8/SVneo cell line显示文摘 | Lunghi L Frigato E Ferretti ME | 2011 | Hum Ceil2011，24，4： | 1 |
| 15 | The stability of hepatitis C virus RNA after storage at 4 degree显示文摘 | Gessoni G Barin P Frigato A | 2000 | J Viral Hepat2000，7，4： | 1 |
| 16 | The stability of hepa- titis C virus RNA after storage at --4 degrees C显示文摘 | Gessoni G Barin P Frigato A | 2000 | J Vi- ral Hepat2000，7，4： | 1 |
| 17 | The Mechanism of Proton Exclusion in the Aquaporin-1 Water Channel显示文摘 | Bert L. de Groot Tomaso Frigato Volkhard Helms Helmut Grubmüller | 2003 | Journal of Molecular Biology2003，，2： | 1 |
| 18 | Effects of cilazapril and amlodipin on kidney function in hypertensive NIDDM patients显示文摘 | Velussi M Brocco E Frigato F | 1996 | Diabetes1996，45，3： | 1 |
| 19 | Effects of eilazapril and amlodipin on kidney function in hypertensive NIDDM pa- tients显示文摘 | Velussi M Brocco E Frigato F | 1996 | Diabetes1996，45，： | 1 |
| 20 | Quantitative ultrasound assessment of bone显示文摘 | Malavolta N Mule R Frigato M | 2004 | Aging Clin Exp Res2004，16，3： | 1 |
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