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| 1 | Benign liver tumors in pediatric patients-Review with emphasis on imaging features显示文摘Benign hepatic tumors are commonly observed in adults,but rarely reported in children.The reasons for this remain speculative and the exact data concerning the incidence of these lesions are lacking.Benign hepatic tumors represent a diverse group of epithelial and mesenchymal tumors.In pediatric patients,most benign focal liver lesions are inborn and may grow like the rest of the body.Knowledge of pediatric liver diseases and their imaging appearances is essential in order to make an appropriate differential diagnosis.Selection of the appropriate imaging test is challenging,since it depends on a number of age-related factors.This paper will discuss the most frequently encountered benign liver tumors in children(infantile hepatic hemangioendothelioma,mesenchymal hamartoma,focal nodular hyperplasia,nodular regenerative hyperplasia,and hepatocellular adenoma),as well as a comparison to the current knowledge regarding such tumors in adult patients.The current emphasis is on imaging features,which are helpful not only for the initial diagnosis,but also for pre- and posttreatment evaluation and follow-up.In addition,future perspectives of contrast-enhanced ultrasound(CEUS) in pediatric patients are highlighted,with descriptions of enhancement patterns for each lesion being discussed.The role of advanced imaging tests such as CEUS and magnetic resonance imaging,which allow for non-invasive assessment of liver tumors,is of utmost importance in pediatric patients,especially when repeated imaging tests are needed and radiation exposure should be avoided. | Liliana Chiorean Xin-Wu Cui Andrea Tannapfel Doris Franke Martin Stenzel Wojciech Kosiak Dagmar Schreiber-Dietrich J?rg Jüngert Jian-Min Chang Christoph F Dietrich | 2015 | World Journal of Gastroenterology2015，21，28： | 16 |
| 2 | Direct ex vivo analysis of dendritic cells in patients with hepatocellular carcinoma显示文摘瞄准:与肝细胞癌(HCC ) 从病人分析树枝状的房间(DC ) 的显型和功能以便在这疾病理解他们的角色。方法:骨髓的的树枝状的房间在 HCC 病人的外部血被枚举。从外部血的天真、刺激的骨髓的的树枝状的房间上的 CD80, CD83, CD86 和 HLA 医生表示被分析。骨髓的的树枝状的房间从外部血被孤立,他们的功能被测试。吞噬作用用 FITC 葡聚糖祷告被分析,肽特殊刺激,在多形核白细胞 dI:dC 之上刺激 allogeneic T 房间和 cytokines 的分泌物的能力被测试。结果:骨髓的的树枝状的房间与 HCC 在病人被减少。在 CD80, CD83, CD86 和 HLA 医生表示的差别都没从 HCC 病人和健康控制在天真、刺激的骨髓的的树枝状的房间上被发现。肽 specific T 房间的正常吞噬作用或刺激与一个损害 allo-stimulatory 能力和减少的 IL-12 分泌物相对照被观察。结论:在病人的 mDCs 的损害 IL-12 生产能导致建议指导治疗可以提高的那 IL-12 的天真的 T 房间的一个损害 stimulatory 能力在 HCC 病人的肿瘤 specific 免疫者回答。 | Lars A Ormandy Anatol Frber Tobias Cantz Susanne Petrykowska Heiner Wedemeyer Monique Hrning Frank Lehner Michael P Manns Firouzeh Korangy Tim F Greten | 2006 | World Journal of Gastroenterology2006，12，20： | 12 |
| 3 | Double-balloon-enteroscopy-based endoscopic retrograde cholangiopancreatography in post-surgical patients显示文摘AIM: To evaluate double balloon enteroscopy (DBE) in post-surgical patients to perform endoscopic retrograde cholangiopancreatography (ERCP) and interventions. METHODS: In 37 post-surgical patients, a stepwise approach was performed to reach normal papilla or enteral anastomoses of the biliary tract/pancreas. When conventional endoscopy failed, DBE-based ERCP was performed and standard parameters for DBE, ERCP and interventions were recorded. RESULTS: Push-enteroscopy (overall, 16 procedures) reached enteral anastomoses only in six out of 37 post-surgical patients (16.2%). DBE achieved a high rate of luminal access to the biliary tract in 23 of the remaining 31 patients (74.1%) and to the pancreatic duct (three patients). Among all DBE-based ERCPs (86 procedures), 21/23 patients (91.3%) were successfully treated. Interventions included ostium incision or papillotomy in 6/23 (26%) and 7/23 patients (30.4%), respectively. Biliary endoprosthesis insertion and regular exchange was achieved in 17/23 (73.9%) and 7/23 patients (30.4%), respectively. Furthermore, bile duct stone extraction as well as ostium and papillary dilation were performed in 5/23 (21.7%) and 3/23 patients (13.0%), respectively. Complications during DBE-based procedures were bleeding (1.1%), perforation (2.3%) and pancreatitis (2.3%), and minor complications occurred in up to 19.1%. CONCLUSION: The appropriate use of DBE yields a high rate of luminal access to papilla or enteral anastomoses in more than two-thirds of post-surgical patients, allowing important successful endoscopic therapeutic interventions. | Martin Raithel Harald Dormann Andreas Naegel Frank Boxberger Eckhart G Hahn Markus F Neurath Juergen Maiss | 2011 | World Journal of Gastroenterology2011，17，18： | 9 |
| 4 | ^(18)F-FDG符合线路显像检测甲状腺癌转移灶的价值显示文摘目的 比较18F 脱氧葡萄糖 (FDG)双探头符合线路SPECT(DHCI)与PET显像检测甲状腺癌转移病灶的价值。方法 2 6例甲状腺癌患者在同 1天分别进行了18F FDGPET和18F FDGDHCI显像 ,患者均已行甲状腺切除术和131I治疗。肿瘤转移病灶大小由计算机自动勾边在PET显像图中测定。结果 2 6例甲状腺癌患者中 ,18F FDGPET共发现 12 6个肿瘤转移病灶 ,其中18F FDGDHCI检测到 92个 (73 % ) ,CT发现 76个 (6 0 % ) ,18F FDGDHCI的病灶检测率明显高于CT(P <0 0 5 )。根据病灶部位分析 ,18F FDGDHCI与PET对转移病灶检测的符合率在头颈部为 6 8% ,胸部为 83% ,而在骨转移病灶的符合率仅为 5 2 % (P <0 0 1)。根据病灶大小分析 ,当肿瘤转移病灶大于 1 5cm时 ,18F FDGDHCI与PET结果的一致率达 98% ;而在 1~ 1 5cm的病灶检测中 ,18F FDGDHCI仅能发现 5 6 % ;当病灶小于 1cm时 ,18F FDGDHCI则难以发现 ,而PET发现的病灶最小直径为 0 7cm。结论 当肿瘤转移病灶的直径大于 1 5cm时 ,18F FDGDHCI与PET具有相似的诊断准确性。 | 黄钢 Tiepolt C Kropp J Franke F 詹惠明 仇建 袁济民 朱翠英 | 2001 | 中华核医学杂志2001，21，1： | 6 |
| 5 | Voltage-induced penetration effect in liquid metals at room temperature显示文摘Room-temperature liquid metal is discovered to be capable of penetrating through macro-and microporous materials by applying a voltage.The liquid metal penetration effects are demonstrated in various porous materials such as tissue paper;thick and fine sponges;fabrics;and meshes.The underlying mechanism is that the high surface tension of liquid metal can be significantly reduced to near-zero due to the voltage-induced oxidation of the liquid metal surface in a solution.It is the extremely low surface tension and gravity that cause the liquid metal to superwet the solid surface^leading to the penetration phenomena.These findings offer new opportunities for novel microfluidic applications and could promote further discovery of more exotic fluid states of liquid metals. | Frank F Yun Zhenwei Yu Yahua He Lei Jiang Zhao Wang Haoshuang Gu Xiaolin Wang | 2020 | National Science Review2020，7，2： | 3 |
| 6 | Determination of heavy metals in activated charcoals and carbon black for Lyocell fiber production using direct solid sampling high-resolution continuum source graphite furnace atomic absorption and inductively coupled plasma optical emission spectrometry显示文摘 | Fábio G. Lepri Daniel L.G. Borges Rennan G.O. Araujo Bernhard Welz Frank Wendler Marcus Krieg Helmut Becker-Ross | 2010 | Talanta2010，，3： | 3 |
| 7 | Capillary equilibria of dislocated crystals 显示文摘 | FRANK F C | 1951 | Acta Cryst1951，4，： | 2 |
| 8 | Extraintestinal manifestations of Helicobacter pylori:A concise review显示文摘Helicobacter pylori(H.pylori)infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies.Increasing evidence demonstrates possible associations to disease states in other organ systems,known as the extraintestinal manifestations of H.pylori.Different conditions associated with H.pylori infection include those from hematologic,cardiopulmonary,metabolic,neurologic,and dermatologic systems.The aim of this article is to provide a concise review of the evidence that supports or refutes the associations of H.pylori and its proposed extraintestinal manifestations.Based on data from the literature,PUD,mucosal associated lymphoid tumors lymphoma,and gastric adenocarcinoma has well-established links.Current evidence most supports extraintestinal manifestations with H.pylori in immune thrombocytopenic purpura,iron deficiency anemia,urticaria,Parkinson’s,migraines and rosacea;however,there is still plausible link with other diseases that requires further research. | Frank Wong Erin Rayner-Hartley Michael F Byrne | 2014 | World Journal of Gastroenterology2014，20，34： | 2 |
| 9 | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase显示文摘 | Thomas F Franke Sung-Il Yang Tung O Chan Ketaki Datta Andrius Kazlauskas Deborah K Morrison David R Kaplan Philip N Tsichlis | 1995 | Cell1995，，5： | 2 |
| 10 | Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial显示文摘 | David Laharie Arnaud Bourreille Julien Branche Matthieu Allez Yoram Bouhnik Jerome Filippi Frank Zerbib Guillaume Savoye Maria Nachury Jacques Moreau Jean-Charles Delchier Jacques Cosnes Elena Ricart Olivier Dewit Antonio Lopez-Sanroman Jean-Louis Dupas F | 2012 | The Lancet2012，，9857： | 2 |
| 11 | Methylsulfonyl and methoxysulfinyl radicals and cations in the gas phase: A variable-time and photoexcitation neutralization-reionization mass spectrometric and ab initio/RRKM study显示文摘 | Frank A J Turecek F | 1999 | J Phys Chem A1999，103，： | 2 |
| 12 | Controls on trace element (Sr–Mg) compositions of carbonate cave waters: implications for speleothem climatic records显示文摘 | Ian J Fairchild Andrea Borsato Anna F Tooth Silvia Frisia Christopher J Hawkesworth Yiming Huang Frank McDermott Baruch Spiro | 2000 | Chemical Geology2000，，3： | 2 |
| 13 | Motor Learning of a Dynamic Balancing Task After Stroke:Implicit Implications for Stroke Rehabilitation显示文摘 | Alison J Otrell Frank F Eves Rich S W Masters | 2006 | Physical Theropy2006，3，86： | 1 |
| 14 | On tin whiskers显示文摘 | Frank F C | 1953 | Philosophical Magazine1953，44，355： | 1 |
| 15 | Tuning of the structure and parameters of a neural network using an improved genetic algorithms显示文摘 | Frank H F Leung H K Lams S H Ling | 2003 | EEE Trans Neural Networks2003，14，1： | 1 |
| 16 | Generalized cap model for geological materials显示文摘 | Sandler I S Frank L Dimaggio F | 1976 | Journal of the geotechnical engineering division(ASCE)1976，102，7： | 1 |
| 17 | Linking objec- tively measured physical activity with objectively meas- ured urban form--findings from SMARTRAQ显示文摘 | Frank L D Schmid T L Sallis J F | 2005 | Amer- ican Journal of Preventive Medicine2005，28，22： | 1 |
| 18 | Correction of clubfoot relapse using Ilizarov,s apparatus in children 8-15 years old显示文摘 | Franke J Grill F Hein G | 1990 | Arch Orthop Trauma Surg1990，110，1： | 1 |
| 19 | Cytochrome P450 family member CYP704B2 catalyzes the omega } - hydrnxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice 显示文摘 | Li H Pinot F Sauveplane V Werck-Reichhart D Diehl P Schreiber L Franke R Zhang P Chert L Gao Y Liang W ZhangD | 2010 | Plant Cell2010，22，1： | 1 |
| 20 | The formation of passivaring internal In2 03 bands in Silver-Indium alloys 显示文摘 | R A Rapp D F Frank J V Armitage | 1964 | Acta Metall1964，12，： | 1 |
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