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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Smoking in schizophrenic patients:A critique of the selfmedication hypothesis显示文摘A common remark among laypeople, and notably also among mental health workers, is that individuals with mental illnesses use drugs as self-medication to allay clinical symptoms and the side effects of drug treatments. Roots of the self-medication concept in psychiatry date back at least to the 1980 s. Observations that rates of smokers in schizophrenic patients are multiple times the rates for regular smoking in the general population, as well as those with other disorders, proved particularly tempting for a self-medication explanation. Additional evidence came from experiments with animal models exposed to nicotine and the identification of neurobiological mechanisms suggesting self-medication with smoking is a plausible idea. More recently, results from studies comparing smoking and non-smoking schizophrenic patients have led to the questioning of the self-medication hypothesis. Closer examination of the literature points to the possibility that smoking is less beneficial on schizophrenic symptomology than generally assumed while clearly increasing the risk of cancer and other smoking-related diseases responsible for early mortality. It is a good time to examine the evidence for the self-medication concept as it relates to smoking. Our approach is to focus on data addressing direct or implied predictions of the hypothesis in schizophrenic smokers. | Francesca Manzella Susan E Maloney George T Taylor | 2015 | World Journal of Psychiatry2015，5，1： | 4 |
| 3 | Nocturnal Hypoxemia Predicts Incident Cardiovascular Complications in Dialysis Patients显示文摘 | Carmine Z Francesca M Giovanni T | 2002 | J Am Soc Nephrol2002，13，： | 1 |
| 4 | Multiparametric 3T MR approch to the assessment of cerebral gliomas: tumor extent and malignancy显示文摘 | Alfonso DC Tommaso S Francesca T | 2006 | Neuroradiology2006，48，9： | 1 |
| 5 | Noc-tumal hypoxemiapredicts incident cardiovascular complication in dialysis patients显示文摘 | Carmine Z Francesca M Giovanni T | 2002 | J Am Soc Nephrol2002，13，3： | 1 |
| 6 | Antioxidant activities of sicilian prickly pear(opuntia ficus indica)fruit extracts and re ducing properties of its betalains: betanin and indicaxanthin显示文摘 | Daniela B Luisa T Francesca D G | 2002 | Agricultural and Food Chemistry2002，50，23： | 1 |
| 7 | Nanophase fluo- rite-structured CeO2-zrO2 catalysts prepared by high-energy mechanical milling 显示文摘 | Alessandro Trovarelli Francesca Zamar Jordi Horca Carla de Leitenburg Giuliano Dolcetti Janos T Kiss | 1997 | Journal of Catalysis1997，169，2： | 1 |
| 8 | Longer dialysis session length is associated with better intermediate outcomes and survival among patients on in-center three times per week hemodialysis: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS) 显示文摘 | Francesca T Jinyao Z Yun L | 2012 | Nephrol Dial Transplant2012，27，11： | 1 |
| 9 | 显示文摘 | Francesca P Sara M Luigi T | 2008 | Water Research2008，156，： | 1 |
| 10 | Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease显示文摘 | Carmine Z Francesca M Giovanni T | 2002 | Am J Soc Nephrorl2002，13，： | 1 |
| 11 | Selective trace enrichment of chlorotriazine pesticides from natural waters and sediment samples using terbuthylazine molecularly imprinted polymers显示文摘 | IMMA F FRANCESCA L ANTAL T | 2000 | Anal Chem2000，72，： | 1 |
| 12 | Tumor Inflammatory Angiogenesis and Its Chemoprevention显示文摘 | Adriana A Francesca T Roberto B | 2005 | Cancer Res2005，65，10： | 1 |
| 13 | Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene☆显示文摘 | Victor R Gordeuk Angela Caleffi Elena Corradini Francesca Ferrara Russell A Jones Oswaldo Castro Onyinye Onyekwere Rick Kittles Elisa Pignatti Giuliana Montosi Cinzia Garuti Innocent T Gangaidzo Z.A.R Gomo Victor M Moyo Tracey A Rouault Patrick MacPhail A | 2003 | Blood Cells Molecules and Diseases2003，，3： | 1 |
| 14 | The effectiveness of continuing education in postoperative pain management:Results from a follow-up study显示文摘 | Ilario G Renato T Francesca F | 2008 | The Journal of Continuing Education in Nursing2008，39，6： | 1 |
| 15 | Lactic acid bacteria isolated from dairy products inhibit genotoxic effect of 4-nitroquinoline- 1-oxide in sos-chromotest显示文摘 | GIOVANNI C J R FRANCESCA T GUIVABBA C | 2002 | System Appl Microbial2002，25，： | 1 |
| 16 | Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes显示文摘 | Thierry T Francesca G Sundeep K | | 0，，： | 1 |
| 17 | Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent and malignancy显示文摘 | Alfonso DC Tommaso S Francesca T | 2006 | Neuroradiology2006，48，： | 1 |
| 18 | Phase II study of a single pegfilgrastim injection as an adjunct to chemotherapy to mobilize stem cells into the peripheral blood of pretreated lymphoma patients显示文摘 | Alessandro I Monica T Francesca B | 2005 | Haematologica2005，90，2： | 1 |
| 19 | Multiparametric 3T MR approach to the assessment of cerebral gliomas:tumor extent and malignancy显示文摘 | Alfonso DC Tommaso S Francesca T | 2006 | Neuroradiology2006，48，9： | 1 |
| 20 | Noc-turnal hypoxemia predicts incident cardiovascular complication in dialysis patients 显示文摘 | Carmine Z Francesca M Giovarmi T | 2002 | J Am Soc blep hrol2002，13，3： | 1 |
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