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| 1 | Total pancreatectomy and islet autotransplantation: A decade nationwide analysis显示文摘AIM: To investigate outcomes and predictors of inhospital morbidity and mortality after total pancreatectomy(TP) and islet autotransplantation. METHODS: The nationwide inpatient sample(NIS) database was used to identify patients who underwent TP and islet autotransplantation(IAT) between 2002-2012 in the United States. Variables of interest were inherent variables of NIS database which included demographic data(age, sex, and race), comorbidities(such as diabetes mellitus, hypertension, and deficiency anemia), and admission type(elective vs nonelective). The primary endpoints were mortality and postoperative complications according to the ICD-9 diagnosis codes which were reported as the second to 25 th diagnosis of patients in the database. Risk adjusted analysis was performed to investigate morbidity predictors. Multivariate regression analysis was used to identify predictors of in-hospital morbidity.RESULTS: We evaluated a total of 923 patients who underwent IAT after pancreatectomy during 2002-2012. Among them, there were 754 patients who had TP + IAT. The most common indication ofsurgery was chronic pancreatitis(86%) followed by acute pancreatitis(12%). The number of patients undergoing TP + IAT annually significantly increased during the 11 years of study from 53 cases in 2002 to 155 cases in 2012. Overall mortality and morbidity of patients were 0% and 57.8 %, respectively. Postsurgical hypoinsulinemia was reported in 42.3% of patients, indicating that 57.7% of patients were insulin independent during hospitalization. Predictors of inhospital morbidity were obesity [adjusted odds ratio(AOR): 3.02, P = 0.01], fluid and electrolyte disorders(AOR: 2.71, P < 0.01), alcohol abuse(AOR: 2.63, P < 0.01), and weight loss(AOR: 2.43, P < 0.01). CONCLUSION: TP + IAT is a safe procedure with no mortality, acceptable morbidity, and achieved high rate of early insulin independence. Obesity is the most significant predictor of in-hospital morbidity. | Reza Fazlalizadeh Zhobin Moghadamyeghaneh Aram N Demirjian David K Imagawa Clarence E Foster Jonathan R Lakey Michael J Stamos Hirohito Ichii | 2016 | World Journal of Transplantation2016，6，1： | 9 |
| 2 | 相对于男性,女性进行冠状动脉造影产生的额外的心血管病风险与严重受损的冠状动脉血流储备,而非阻塞性疾病相关显示文摘与男性相比,女性的心血管病死亡率更高,但是阻塞性冠状动脉疾病(coronary artery disease,CAD)在女性中不太普遍。冠状动脉血流储备(coronary flow reserve,CFR)是大、小血管CAD和心肌缺血的综合测量指标,可识别出具有心血管病死亡风险的患者,但其在临床实践中不是常规测量的指标。该研究试图调查性别、CFR和血管造影CAD严重程度对不良心血管事件的影响。 | 刘莉 叶鹏 Taqueti VR Shaw LJ Cook NR Murthy VL Shah NR Foster CR Hainer J Blankstein R Dorbala S Di Carli MF | 2016 | 中华高血压杂志2016，24，11： | 2 |
| 3 | WONCA研究论文摘要汇编(一百二十七)——全科医疗中腰痛分层治疗(IMPaCT Back)的效果:前瞻性-群组序列对照研究显示文摘目的此研究将明确在全科医疗中腰痛风险-层化治疗对医生的临床行为、患者的治疗效果及成本的作用。方法腰痛分层治疗研究(通过靶向疗法以改善患者的治疗)按照前瞻性-群组序列对照研究方法,将接受全科医疗的患者分为两组,即干预前期组(常规治疗6个月)与干预后期组(层化治疗12个月),此研究有64名全科医生参与并结合了理疗服务,纳入了1 647例患有腰痛的成人。利用风险层化工具将患者按功能障碍分为:低、中、高风险组,并提供风险-匹配治疗。使用罗兰-摩理斯腰背痛生活障碍问卷(Roland-Morris Disability Questionnaire)对治疗6个月患者的功能改善进行初步评估。研究过程将关注医生根据理疗、诊断性检查、用药处方和疾病证明而做出的与风险相应的行为改变。成本效应分析评估了所增加的质量调整寿命年数及腰部-相关医疗的成本。并分析治疗意向。结果 922例患者(干预前期368例,干预后期554例)符合基线标准。在治疗6个月组的随访中,罗兰-摩理斯腰背痛生活障碍问卷(Roland-Morris Disability Questionnaire)分数均差0.7〔95%CI(0.1,1.4)〕,提示与常规治疗相比,层化治疗均差小但获益显著;高危组均差大,为2.3〔95%CI(0.8,3.9)〕,是临床重要差异。而在干预后期组,患者不能工作的平均时间相较于干预前期组要少50%(4 vs 8 days,P=0.03);被给予疾病证明的患者比例也要低30%;医疗成本也有所减少。结论全科医疗中腰痛分层治疗方案的实施,在未增加医疗成本的前提下,显著改善了患者功能障碍的治疗效果,并使其不能工作的时间减半。建议推广应用。 | Foster NE Mullis R Hill JC 周淑新 | 2014 | 中国全科医学2014，17，19： | 2 |
| 4 | Solubility of o-hydroxybenzoic acid in supercritical carbon dioxide 显示文摘 | Gurdial G S Nail R Foster | 1991 | Ind Eng Chem Res1991，30，： | 2 |
| 5 | Oxidation products formed from gaseous alkane by the bacterium Pseudomonas metharica 显示文摘 | Leadbetter E R Foster J W | 1959 | Arch Biochem Biophys1959，82，： | 1 |
| 6 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 7 | The effects of sulfonate molecular weight and salt concentration on the interracial tension of oil-brine-surfactant systems显示文摘 | Nillson P M Murphy C L Foster W R | 1976 | SPE58121976，，： | 1 |
| 8 | Detail-preserving ranked-order based filter for image processing显示文摘 | Arce G Foster R | 1989 | IEEE Traus Acoust Speech Signal Processing1989，37，1： | 1 |
| 9 | The definition and classification of glaucoma in prevalence surveys 显示文摘 | FOSTER P J BUHRMANN R QUIGLEY H A | 2002 | Br J Ophthalmol2002，86，2： | 1 |
| 10 | Transport of soil particles by shallow flow显示文摘 | Foster G R Meyer L D | 1972 | Transaction of the ASAE1972，15，1： | 1 |
| 11 | RUSLE,revided:Status,question,answers,and the future显示文摘 | Renard K G Foster G R | 1994 | Soil and water Conservation1994，49，3： | 1 |
| 12 | Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway显示文摘 | Foster J S Fernando R I Ishida N | 2003 | J Biol Chem2003，278，41： | 1 |
| 13 | D1 dopamine receptor regulates alcohol-motivated behaviors in the bed nucleus of the stria terminalis in alcohol-preferring(P) rats显示文摘 | Eiler WJ 2nd Seyoum R Foster KL | 2003 | Synapse2003，48，1： | 1 |
| 14 | Levobupivacaine:a review of its pharmacology and use as a local anaesthetic显示文摘 | FOSTER R H MARKHAM A | 2000 | Drugs2000，59，： | 1 |
| 15 | The design of non-flexural members with normal and high strength concrete 显示文摘 | Foster S J Gilbert R I | 1996 | ACI Structural Journal1996，93，1： | 1 |
| 16 | RUSLE; Revised universal soil Loss equation 显示文摘 | RENARD K G FOSTER G R WEESIES G A | 1991 | Journal of Soll and Water Conservation1991，46，： | 1 |
| 17 | Progression and regression of sleep-disordered breathing with changes in weights the sleep heart health study 显示文摘 | Newman AB Foster G Givelber R | 2005 | Arch Intern Med2005，165，20： | 1 |
| 18 | Proton pump inhibitors are associated w ith evaluat ion of faecal calprotectin and may affect specif icity 显示文摘 | Poullis A Foster R Mendall MA | 2003 | Eur J Gastroenterol Hepatol2003，15，5： | 1 |
| 19 | The attending nurse caring model: in-tegrating theory, evidence and advanced caring--healing ther- apeutics for transforming professional practice显示文摘 | Watson J Foster R | 2003 | Journal of Clinical Nursing:2003，12，3： | 1 |
| 20 | Effect of several Chinese natural heal thproducts of human cytochromeP450 metabolism 显示文摘 | Foster BC Vandenhoek S Tang R | 2002 | JPharmPharmSci2002，5，2： | 1 |
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