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| 1 | Management of liver transplantation biliary stricture: Results from a tertiary hospital显示文摘AIM: To review results of endoscopic treatment for anastomotic biliary strictures after orthotopic liver transplantation(OLT) during an 8-year period. METHODS: This is a retrospective review of all endoscopic retrograde cholangiopancreatographys(ERCPs) performed between May 2006 and June 2014 in deceased OLT recipients with anastomotic stricture at a tertiary care hospital. Patients were divided into 2 groups, according to the type of stent used(multiple plastic or covered self-expandable metal stents), which was chose on a case-by-case basis and their characteristics. The primary outcome was anastomotic stricture resolution rate determined if there was no more than a minimum waist at cholangiography and a 10 mm balloon could easily pass through the anastomosis with no need for further intervention after final stent removal. Secondary outcomes were technical successrate, number or ERCPs required per patient, number of stents placed, stent indwelling, stricture recurrence rate and therapy for recurrent anastomotic biliary stricture(AS). Stricture recurrence was defined as clinical laboratorial and/or imaging evidence of obstruction at the anastomosis level, after it was considered completely treated, requiring subsequent interventional procedure.RESULTS: A total of 195 post-OLT patients were assessed for eligibility. One hundred and sixty-four(164) patients were diagnosed with anastomotic biliary stricture. ERCP was successfully performed in 157/164(95.7%) patients with AS, that were treated with either multiple plastic(n = 109) or metallic billiary stents(n = 48). Mean treatment duration, number of procedures and stents required were lower in the metal stent group. Acute pancreatitis was the most common procedure related complication, occurring in 17.1% in the covered self-expandable metal stents(c SEMS) and 4.1% in the multiple plastic stent(MPS) group. Migration was the most frequent stent related complication, observed in 4.3% and 5.5%(c SEMS and MPS respectively). Stricture resolution was achieved in 86.8% in the c SEMS group and in 91% in MPS group. Stricture recurrence after a median follow up of 20 mo was observed in 10(30.3%) patients in the c SEMS and 7(7.7%) in the plastic stent group, a statistically significant difference(P = 0.0017). Successful stricture resolution after secondary treatment was achieved in 66.6% and 62.5% of patients respectively in the c SEMS and plastic stents groups. CONCLUSION: Multiple plastic stents are currently the first treatment option for AS in patients with duct-toduct anastomosis. c SEMS was associated with increased pancreatitis risk and higher recurrence rate. | Fernanda Prata Martins Michel Kahaleh Angelo P Ferrari | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，7： | 10 |
| 2 | 心率作为冠心病与左室收缩障碍患者的预后危险因素(BEAUTIFUL):一项随机、对照试验的一个亚组分析显示文摘背景BEAUTIFUL研究对降心率药物伊伐布雷定的发病率与病死率收益进行了评估。BEAUTIFUL试验中的安慰剂组是由稳定型冠心病与左室收缩功能障碍的大型患者队列组成。我们对该安慰剂组进行了亚组分析,旨在检验这样一种假设,即基线静息心率升高是心血管疾病发病与死亡的标志。
方法采用Cox比例风险模型,对心率≥70次/min患者(2693例)以及〈70次/min患者(2745例)进行对比,分析基线静息心率与心血管结局之间的关系。将心率作为一个连续变量,并采用更为精细的心率分类进行其他分析。
结果在对基线特征进行校正后,心率≥70次/min患者的心血管疾病死亡(34%,P=0.0041)、心力衰竭入院(53%,P=0.0001)、心肌梗死入院(46%,P=0.0066)及冠状动脉血运重建(38%,P=0.037)风险升高。心率每升高5次/min,患者的心血管疾病死亡(8%,P=0.0005)、心力衰竭入院(16%.P〈0.0001)、心肌梗死入院(7%,P=0.052)及冠状动脉血运重建(8%,P=0.034)风险亦升高。对心率精细分组的分析表明,心率〉70次/min患者的病死率与心力衰竭发生率持续升高,但这种相关性在冠状动脉结局方面并不显著。对于心力衰竭结局而言,静息心率对早期事件的预测价值较晚期事件的预测价值更强。
结论在冠心病和左室收缩功能障碍的患者中,心率升高(≥70次/min)意味着心血管疾病结局风险升高,同时对心力衰竭相关性结局与冠状动脉事件相关性结局有着不同的影响。 | Kim Fox Ian Ford P Gabriel Steg Michal Tendera Michele Robertson Roberto Ferrari 罗亮(译) | 2008 | 世界临床医学2008，2，6： | 5 |
| 3 | Electron transfer in a new highly conducting donor-acceptor complex显示文摘 | Ferraris J P Cowan D O Walatka V | 1973 | J Am Chem Soc1973，95，： | 2 |
| 4 | 抗高血压药与血清脂蛋白及葡萄糖代谢显示文摘理想的抗高血压药不仅能有效地控制血压、显著降低脑血管病死率,还应减少冠脉并发症。心肌肥厚、血清电解质、血管紧张素Ⅱ、儿茶酚胺、凝血因子以及脂蛋白和葡萄糖代谢与冠脉危险因素的关系尤为引人注目。作者综述了不同类型的抗高血压药对脂质及糖代谢的影响,指出临床上使用的大多数降压药对其具有有益作用。 | Ferrari P 杨友田 王洵 | 1992 | 国外医学(老年医学分册)1992，13，2： | 2 |
| 5 | Joining of carbon-carbon composites for thermonuclear fusion applications显示文摘 | Lemoine P Ferraris M | 1997 | Journal of the American Ceramic Society1997，80，1： | 1 |
| 6 | In vivo fractional Pi absorption and NaPi-II mRNA expression in rainbow trout are upregulated by dietary P restriction 显示文摘 | SUGIURA S H McDANIEL N K FERRARIS R P | 2003 | Am J Physiol Regul Integr Comp Physiol2003，285，： | 1 |
| 7 | Intestinal transport during fasting and malnutrition 显示文摘 | FERRARIS R P CAREY H V | 2000 | Annu Rev Nutr2000，20，： | 1 |
| 8 | Excimer laser intrastromal keratomileusis显示文摘 | Buratto L Ferrari M Rama P | 1992 | Am J Ophthalmol1992，113，3： | 1 |
| 9 | Mea- suring internal electric fields in organic light - emitting diodes using electroabsorption spectroscopy 显示文摘 | CAMPBELL LAN H FERRARIS J P HAGLER T W | 1997 | Polym Advan Technol1997，8，： | 1 |
| 10 | Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial显示文摘 | Benjamin M Scirica Marc P Bonaca Eugene Braunwald Gaetano M De Ferrari Daniel Isaza Basil S Lewis Felix Mehrhof Piera A Merlini Sabina A Murphy Marc S Sabatine Michal Tendera Frans Van de Werf Robert Wilcox David A Morrow | 2012 | The Lancet . 2012 (9850)2012，，9850： | 1 |
| 11 | Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis显示文摘 | Muratori P Muratori L Ferrari R | 2003 | Am J Gasteroenterol2003，，2： | 1 |
| 12 | Transient behavior of a sprag-type over-running clutch: An experimental study显示文摘 | VENAY P FERRARIS G | 2001 | Journal of Sound and Vibration2001，248，3： | 1 |
| 13 | Contibutions of different Na/Pi cotransporter isoforms to dietary regulation of P transport in the pyloric caeca and intestine of rainbow trout 显示文摘 | SUGIURA S H FERRARIS R P | 2004 | J Exp Biol2004，207，： | 1 |
| 14 | In vitro characterization of coevaporates containing chitosan for colonic drug delivery 显示文摘 | Ferrari P C Oliveira G F Chibebe F C S | 2009 | Carbo Polym2009，78，： | 1 |
| 15 | Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C reactive protein and markers of bone resorption in postmenopausal women 显示文摘 | Ferrari SL Ahn-Luong L Garnero P | 2003 | J Clin Endoerinol Metab2003，88，： | 1 |
| 16 | TRBAC:A temporal role -based access control model显示文摘 | Bertino E Bonatti P A Ferrari E | 2001 | ACM Transactions on Information and System Security2001，4，3： | 1 |
| 17 | The Ca2 + concentration of the endoplasmic retieulum is a key determinant of ceramide-induced ap- optosis : significance for the molecular mechanism of Bcl - 2 action 显示文摘 | Pinton P Ferrari D Papizzi Z | 2001 | E MBO J2001，20，11： | 1 |
| 18 | Joining of carboncarbon composites for thermonuclear fusion applications显示文摘 | Salvo M Lemoine P Ferraris M | 1997 | J Am Ceram Soc1997，80，1： | 1 |
| 19 | Chitosan -pectin multiparticulate systems associated with enteric polymers for colonic drug delivery显示文摘 | Oliveira G F Ferrari P C Carvalho L Q | 2010 | Carbo Polym2010，82，： | 1 |
| 20 | Development of a new ELISA for serum periostin:evaluation of growth-related changes and bisphospho- nate treatment in mice显示文摘 | Conti6 S Voorzanger-Rousselot N Litvin J Bonnet N Ferrari S Clezardin P | 2010 | Calcif Tissue Int2010，87，： | 1 |
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