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| 1 | Early changes of graft function,cytokines and superoxide dismutase serum levels after donor liver denervation and Kupffer cell depletion in a rat-to-rat liver transplantation model显示文摘BACKGROUND:Hepatic reperfusion injury may cause acute inflammatory damage,producing significant organ dysfunction,and is an important problem in liver transplantation.This experiment aimed to study early changes of hepatic function after donor liver denervation and Kupffer cell depletion in rat-to-rat liver transplantation and to evaluate the effect of pre-treatment on liver reperfusion injury.METHODS:Donor rats were divided into four groups:control group;group G was pre-treated with gadolinium chloride(G),an inhibitor of Kupffer cells;group H with hexamethonium(H),a sympathetic ganglionic blocking agent;and group HG,with combined H and G pre-treatment.Under the same conditions,serum alanine aminotransferase(ALT),arterial ketone body ratio(AKBR),tumor necrosis factor-alpha(TNF-α),interleukin-6(IL-6),and superoxide dismutase(SOD)of recipient rats were assessed at 4,8,16 and 24 hours after liver transplantation.Histological studies of the grafts were compared.RESULTS:HG pre-treatment significantly decreased ALT,TNF-α,and IL-6 levels,increased AKBR and SOD levels,and demonstrated less pathological damage at 8,16 and 24 hours compared with the control group.Similar trends were also found in the other groups(G and H).However,the differences among them were not significant at 4 post-operative hours.CONCLUSIONS:Donor denervation and Kupffer cell depletion had preventive effect on liver reperfusion injury.HG pre-treatment is a feasible and reproducible method to protect grafts from reperfusion injury. | Catena Marco Ferla Gianfranco | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，2： | 7 |
| 2 | Liver transplantation in the treatment of severe iatrogenic liver injuries显示文摘The place of liver transplantation in the treatment of severe iatrogenic liver injuries has not yet been widely discussed in the literature. Bile duct injuries during cholecystectomy represent the leading cause of liver transplantation in this setting, while other indications after abdominal surgery are less common. Urgent liver transplantation for the treatment of severe iatrogenic liver injury may-represent a surgical challenge requiring technically difficult and time consuming procedures. A debate is ongoing on the need for centralization of complex surgery in tertiary referral centers. The early referral of patients with severe iatrogenic liver injuries to a tertiary center with experienced hepato-pancreatobiliary and transplant surgery has emerged as the best treatment of care. Despite widespread interest in the use of liver transplantation as a treatment option for severe iatrogenic injuries, reported experiences indicate few liver transplants are performed. This review analyzes the literature on liver transplantation after hepatic injury and discusses our own experience along with surgical advances and future prospects in this uncommon transplant setting. | Andrea Lauterio Riccardo De Carlis Stefano Di Sandro Fabio Ferla Vincenzo Buscemi Luciano De Carlis | 2017 | World Journal of Hepatology2017，9，24： | 4 |
| 3 | Hilar Cholangiocarcinoma: Preoperative Liver Optimization with Multidisciplinary Approach. Toward a Better Outcome显示文摘 | Francesca Ratti Federica Cipriani Fabio Ferla Marco Catena Michele Paganelli Luca A. M. Aldrighetti | 2013 | World Journal of Surgery2013，，6： | 2 |
| 4 | Laparoscopic liver resections for hepatocellular carcinoma. Is it a feasible option for patients with liver cirrhosis?显示文摘 | R. Santambrogio L. Aldrighetti M. Barabino C. Pulitanò M. Costa M. Montorsi G. Ferla E. Opocher | 2009 | Langenbeck’s Archives of Surgery2009，，2： | 2 |
| 5 | Sertraline versusother antidepressive agents for depression 显示文摘 | Cipriani A La Ferla T Furukawa TA | 2010 | Cochrane Database Syst Rev2010，14，00： | 1 |
| 6 | miR-20b Modulates VEGFexpression by targeting HIF-1 alpha and STAT3 in mcf-7 breastcancer cells显示文摘 | Cascio S D Andrea A Ferla R | 2010 | J Cell Physiol2010，224，1： | 1 |
| 7 | Global Cancer Statistics显示文摘 | Parkin DM Pisani P Ferla J | 1999 | CA cancer J Clin1999，49，： | 1 |
| 8 | Moxifloxacin: comparative inhibitory bactericidal activity against susceptible and multidrug resistant Gram positive bacteria显示文摘 | Speciale A Aleo G Ferla K La | 1999 | Drugs1999，，： | 1 |
| 9 | Founder mutations in BRCA 1 and BRCA2 genes显示文摘 | Ferla R Calo V Caseio S | 2007 | Ann Oncol2007，18，6： | 1 |
| 10 | Laparoscopic splenectomy in patients with hereditary spherocytosis: report on 12 consecutive cases 显示文摘 | Vecchio R Intagliata E Ferla F | 2013 | Updates Surg2013，65，4： | 1 |
| 11 | Laparoscopic hepatic left lateral sectionectomy using the LaparoEndoscopic Single Site approach: evolution of minimally invasive liver surgery 显示文摘 | Aldrighetti L Guzzetti E Ferla G | 2011 | J Hepatobiliary Pancreat Sci2011，18，1： | 1 |
| 12 | Alzheimer's disease 显示文摘 | Querfurth HW La Ferla FM | 2010 | N EnglJ Med2010，36，2： | 1 |
| 13 | miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer celis显示文摘 | Cascio S D'Andrea A Ferla Rt | 2010 | J Cell Physiol2010，224，1： | 1 |
| 14 | Mechanisms of disease Alzheimer’s disease显示文摘 | Querfurth HW La Ferla FM | 2010 | N Engl J Med2010，362，4： | 1 |
| 15 | Glycoconjugate and oligosaccharide mimetics by chemoselective ligation显示文摘 | FRANCESCO PERI LAURA CIPOLLA BARBARA LA FERLA | 2003 | C R Chimie2003，6，： | 1 |
| 16 | Optimization of the trade-of between switching speed of the internal diode and on-resistance in gold and platinum implanted power metal-oxide-semi -conductor devices显示文摘 | Catania M. F Frisina F Tavolo N Ferla G Cof a S Campisano S U | | 0，，： | 1 |
| 17 | PREOPERATIVE METHYLPREDNISOLONE ADMINISTRATION MAINTAINS COAGULATION HOMEOSTASIS IN PATIENTS UNDERGOING LIVER RESECTION: IMPORTANCE OF INFLAMMATORY CYTOKINE MODULATION显示文摘 | Carlo Pulitanò Luca Aldrighetti Marcella Arru Renato Finazzi Marco Catena Eleonora Guzzetti Laura Soldini Laura Comotti Gianfranco Ferla | 2007 | Shock2007，，4： | 1 |
| 18 | Esfirnates of worldwideburden of cancer in 2008: Globoean 2008显示文摘 | Ferla YJ Shin HR Bray F | 2010 | Intemational Jour-nal of Cancer2010，127，12： | 1 |
| 19 | miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells 显示文摘 | Cascio S D' BAndrea A Ferla R Surmacz E Gulotta E Amodeo V | 2010 | J Cell Physiol2010，224，1： | 1 |
| 20 | miR-20b modulates VEGF expression by targeting H IF-1 alpha and STAT3 in mcf-7 breast cancer cells显示文摘 | Cascio S D'Andrea A Ferla R | | 0，，01： | 1 |
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