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6篇 您的检索式:作者名="Ferda G"
    题名 作者 年代 出处 被引量
1Keratinocyte 生长 factor-2 和自体同源的浆液加强处于在老鼠的角膜损坏的间充质的干细胞的再生效果显示文摘AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells(MSCs)cultured with or without keratinocyte growth factor(KGF-2)and autologous serum(AS)on amniotic membrane(AM).Many patients are blind and devastated by severe ocular surface diseases due to limbal stem cell deficiency.Bone marrow-derived MSCs are potential sources for cellbased tissue engineering to repair or replace the corneal tissue,having the potential to differentiate to epithelial cells.METHODS:The study included 5 groups each including 10 female'Sprague Dawley'rats in addition to20 male rats used as bone marrow donors.Group I rats received AM+MSCs,Group II rats AM+MSCs cultured with KGF-2,Group III rats AM+MSCs cultured with KGF-2+AS,Group IV rats only AM and Group V rats,none.AS was derived from blood drawn from male rats and bone marrow was obtained from the femur and tibia bones of the same animals.Therapeutic effect was evaluated with clinical,histopathological and immunohistochemical assessment.MSC engraftment was demonstrated via detection of donor genotype(Y+)in the recipient tissue(X)with polymerase chain reaction.RESULTS:Corneal healing was significantly better in Groups I-III rats treated with MSC transplantation compared to Group IV and Group V rats with supportive treatment only.The best results were obtained in Group III rats with 90%transparency,70%lack of neovascularization,and 100%epithelium damage limited to less than 1/4 of cornea.CONCLUSION:We suggest that culture of MSCs with KGF-2 and AS on AM is effective in corneal repair in case of irreversible damage to limbal stem cells.Ferda Alpaslan Pinarli Gülsen Okten Umit Beden Tunc Fisgin Mehmet Kefeli Nurten Kara Feride Duru Leman Tomak 2014International Journal of Ophthalmology(English edition)2014,7,2:4
2Resveratrol and Adipose-derived Mesenchymal Stem Cells Are Effective in the Prevention and Treatment of Doxorubicin Cardiotoxicity in Rats显示文摘Ferda Alpaslan P?narl? Nilüfer N. Turan Faruk Gü?lü P?narl? Arzu Okur Devrim S?nmez Tulga Ulus Aynur O?uz Ceyda Karadeniz Tuncay Deliba?? 2013Pediatric Hematology-Oncology2013,,3:1
3Modulation of Postoperative Scarring with Tacrolimus and Octreotide in Experimental Glaucoma Filtration Surgery显示文摘Sermal Arslan Orhan Aydemir Mete ler Adile Ferda Da&gbreve l&inodot 2012Current Eye Research2012,,:1
4The synthesis, spectroscopic and thermal properties of phenoxycyclotriphosphazenyl-substituted phthalocyanines显示文摘Ferda Hac?velio?lu Mahmut Durmu? Serkan Ye?ilot Ay?e Gül Gürek Adem K?l?? Vefa Ahsen 2008Dyes and Pigments2008,,1:1
5Biosorption of phenol by immobilized activated sludge in a continuous packed bed: prediction of breankthroug curves 显示文摘Zümriye A Ferda G 2004Process Biochemistry2004,39,:1
6Patients with iron deficiency anemia have an increased prevalence of gallstones显示文摘Gülsüm Emel Pamuk Hasan ümit Ferda Harmandar Nesibe Ye?il 2009Annals of Hematology2009,,1:1
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