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| 1 | 复方阿胶浆辅助治疗登革出血热患者40例显示文摘目的观察复方阿胶浆辅助治疗登革出血热患者的临床疗效。方法将80例患者随机分为治疗组和对照组各40例,两组均给予综合治疗,包括降温、止痛、对症处理、辅助用药等,治疗组在此基础上2天后开始口服复方阿胶浆,每日2次,每次20ml,连用4天。观察两组综合疗效并测定患者血小板、血细胞比容和血红蛋白的水平。结果治疗组、对照组总有效率分别为97.5%、72.5%,治疗组总有效率明显高于对照组(P<0.05)。治疗组在第4次和第8次治疗后,血细胞比容均明显下降(P<0.05);在第8次治疗后,血小板及血红蛋白明显升高(P<0.05)。在第4次和第8次治疗后,治疗组血细胞比容、血小板和血红蛋白改善明显优于对照组(P<0.05)。结论复方阿胶浆辅助治疗登革出血热患者可提高临床疗效,能显著升高患者的血小板、血红蛋白水平,使血细胞比容显著下降。 | Fenny Yunita1 方喆 聂洪霞 尤金花 Jusuf Kristianto | 2013 | 中医杂志2013，54，8： | 4 |
| 2 | Synergistic anti-liver cancer effects of curcumin and total ginsenosides显示文摘BACKGROUND Liver cancer is the sixth most frequently occurring cancer in the world and the fourth most common cause of cancer mortality.The pathogenesis of liver cancer is closely associated with inflammation and immune response in the tumor microenvironment.New therapeutic agents for liver cancer,which can control inflammation and restore cellular immunity,are required.Curcumin(Cur)is a natural anti-inflammatory drug,and total ginsenosides(TG)are a commonly used immunoregulatory drug.Of note,both Cur and TG have been shown to exert anti-liver cancer effects.AIM To determine the synergistic immunomodulatory and anti-inflammatory effects of Cur combined with TG in a mouse model of subcutaneous liver cancer.METHODS A subcutaneous liver cancer model was established in BALB/c mice by a subcutaneous injection of hepatoma cell line.Animals were treated with Cur(200 mg/kg per day),TG(104 mg/kg per day or 520 mg/kg per day),the combination of Cur(200 mg/kg per day)and TG(104 mg/kg per day or 520 mg/kg per day),or 5-fluorouracil combined with cisplatin as a positive control for 21 d.Tumor volume was measured and the protein expression of programmed cell death 1 and programmed cell death 1 ligand 1(PD-L1),inflammatory indicators Toll like receptor 4(TLR4)and nuclear factor-κB(NF-κB),and vascular growth-related factors nitric oxide synthases(iNOS)and matrix metalloproteinase 9 were analyzed by Western blot analysis.CD4+CD25+Foxp3+regulatory T cells(Tregs)were counted by flow cytometry.RESULTS The combination therapy of Cur and TG significantly inhibited the growth of liver cancer,as compared to vehicle-treated animals,and TG showed dose dependence.Cur combined with TG-520 markedly decreased the protein expression of PD-L1(P<0.0001),while CD4+CD25+Foxp3+Tregs regulated by the PD-L1 signaling pathway exhibited a positive correlation with PD-L1.Cur combined with TG-520 also inhibited the cascade action mediated by NF-κB(P<0.0001),thus inhibiting the TLR4/NF-κB signalling pathway(P=0.0088,P<0.0001),which is associated with inflammation and acts on PD-L1.It also inhibited the NF-κB-MMP9 signalling pathway(P<0.0001),which is associated with tumor angiogenesis.CONCLUSION Cur combined with TG regulates immune escape through the PD-L1 pathway and inhibits liver cancer growth through NF-κB-mediated inflammation and angiogenesis. | Zhe Deng Xiao-Yan Xu Fenny Yunita Qing Zhou Yong-Rong Wu Yu-Xing Hu Zhi-Qi Wang Xue-Fei Tian | 2020 | World Journal of Gastrointestinal Oncology2020，12，10： | 4 |
| 3 | 从邻国传统医学现状谈中西医并存医学模式显示文摘中国医学类别主要分为中国传统医学(中医)、现代医学(西医)。中医学科、西医学科在医疗、教育、科研等方面长期并存,中西医结合是中国在医疗卫生事业上的重大成就之一。现代医学的更新日新月异,随着传统医学的精华和科学技术的发展,中西医结合探索生命科学和寻求成效更大的医疗保健的发展是客观的必然存在和发展的现实,这是社会和公众的必然选择之一。中西医结合虽然取得了不少成绩,但未能形成系统的理论。 | 田莎 田雪飞 徐晓燕 宋祯彦 柏莹 fenny 成绍武 | 2017 | 大学教育2017，，5： | 3 |
| 4 | Isozyme inheritance and variation in Actinidia显示文摘 | Huang H W Fenny D Wang Z R Jiang Z W Huang R H Wang S M | 1997 | Heredity1997，78，： | 2 |
| 5 | The CELLULOSE-SYNTHASE LIKE C (CSLC) Family of Barley Includes Members that Are Integral Membrane Proteins Targeted to the Plasma Membrane显示文摘纤维素象 SYNTHASE 一样 C (CSLC ) 家庭是在被认为在苔藓和脉管的植物的分叉前产生了的 CELLULOSE SYNTHASE/CELLULOSE 象 SYNTHASE 一样(CESA/CSL ) 多糖 synthase 总科以内的一个古老的系。作为在 flowering 植物的研究, Arabidopsis 建议了合成( 1,4 )-- xyloglucan ( XyG )的 glucan 脊梁,,拴住邻近的纤维素 microfibrils 到对方的墙多糖为 CSLC 的可能的功能, CSLC 功能在大麦( Hordeum vulgare L.)被调查,有在它的墙中的 XyG 的低数量的种。四大麦 CSLC 基因被识别(指明的 HvCSLC14 ) 。种系发生的分析在 flowering 植物揭示 CSLC 的三很好支持的 clades,与有在二这些 clades 的代表的大麦。四大麦 CSLC 在各种各样的纸巾被表示,与,包括有主要、第二等的房间墙的房间在在所有房间检测抄本的 situ PCR coleoptile 和根打字。合作表示分析证明 HvCSLC3 并列地与通常认为的 XyG xylosyltransferase 基因被表示。两免疫 -- 他们和膜分别证明 HvCSLC2 位于大麦的血浆膜暂停有教养的房间并且不在象 endoplasmic 那样的内部膜蜂窝胃或 Golgi 仪器。基于我们多糖合成的亚 cellular 地点的当前的知识,我们断定 CSLC 家庭可能包含多糖 synthase 的超过一种类型。 | Fenny M. Dwivany Dina Yulia Rachel A, Burton Neil J. Shirley Sarah M. Wilson Geoffrey B, Fincher Antony Bacic Ed Newbigin Monika S. Doblin | 2009 | Molecular Plant2009，2，5： | 2 |
| 6 | Microelectrode Recording of Tissue Neural Oscillations for a Bionic Olfactory Biosensor显示文摘 | Qingjun Liu Fenni Zhang Ning Hu Hua Wang Kuen Jimmy Hsia Ping Wang | 2012 | Journal of Bionic Engineering2012，9，4： | 2 |
| 7 | 健康教育和减轻应激训练对慢性乙型肝炎患者应激水平的影响比较显示文摘目的:比较健康教育与减轻应激训练对慢性乙型肝炎(简称慢性乙肝)患者应激水平的影响。方法:将120名门诊慢性乙肝患者随机分成对照组、健康教育组、减轻应激训练组,每组30名,在对照组接受门诊医护人员的一般信息咨询和处理的基础上,健康教育组和减轻应激训练组分别进行为期4个月的健康教育和减轻应激训练,在干预前后,采用乙肝应激量表(PSSH)评定三组患者的应激水平。结果:干预前后对照组PSSH得分差异无统计学意义(P>0.05),健康教育组和减轻应激训练组PSSH得分差异有统计学意义(P<0.01);减轻应激训练组的实验处理效果优于健康教育组的,差异具有统计学意义(P<0.01)。结论:对于降低慢性乙肝患者的应激水平,减轻应激训练比健康教育效果更佳。 | 曾慧 曾慧 Kristopher Fennie 姚树桥 张丽平 赵晓敏 | 2009 | 湖南医科大学学报(社会科学版)2009，11，4： | 2 |
| 8 | Generation of three dimensional finite element models of restored human teeth using micro-CT techniques 显示文摘 | Verdonschot N Fennis WM Kujs RH | 2001 | Int J Prosthodont2001，14，4： | 1 |
| 9 | You are what you wear: Brand personality influences on consumer impression formation显示文摘 | Bob M. Fennis Ad Th. H. Pruyn | 2006 | Journal of Business Research2006，，： | 1 |
| 10 | Looking is not seeing and listening is not hearing:effect of an intervention to enhance auditory skills of graduate-entry nursing students显示文摘 | Pellico LH Duffy TC Fennie KP | | 0，，04： | 1 |
| 11 | Fuzzy logic modelling of state-of-charge and available capacity of nickel/metal hydride batteries显示文摘 | Pritpal Singh Craig Fennie David Reisner | 2004 | Journal of Power Sources2004，，2： | 1 |
| 12 | Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds,pariculate cortico-cancellous bone grafts and platelet rich plasma in goats显示文摘 | Fennis JP Stoelinga PJ Jansen JA | 2004 | Int J Oral Maxillofac Surg2004，33，1： | 1 |
| 13 | Fuzzy logic modeling of state-of-charge and available capacity of nickel/metal hydride batteries显示文摘 | SINGH P FENNIE C REISNER J D | | 0，，： | 1 |
| 14 | 显示文摘 | FENNY A | 1992 | Water Supply1992，10，4： | 1 |
| 15 | CD34^+- endothelial cell lines derived from murine yolk sac induce the proliferation and differentiation of yolk sac CD34^+- hematopoietic progenitors 显示文摘 | Fennie C Cheng J D Young P | 1995 | Blood1995，86，12： | 1 |
| 16 | CD34 endothelial cell lines de-rived from murine yolk sac induce the proliferation and diferentiationofyolk sac CD34 hematopoietic progenitors显示文摘 | Fennie C Cheng J Dowbenko D | 1995 | Blood1995，86，12： | 1 |
| 17 | Mandibular reconstruction: A histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats显示文摘 | Fennis JP Stoelinga PJ Jansen JA | 2004 | Int J Oral Maxillofac Surg2004，33，1： | 1 |
| 18 | Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vi- vo显示文摘 | Ley K Gaehtgens P Fennie C | 1991 | Blood1991，77，： | 1 |
| 19 | Glycosylation - dependent cell adhesion molecule 1 ( GlyCAM1 ) mucin is expressed by lactating mammary gland epithelial cells and is present in milk 显示文摘 | DOWBENKO D KIKUTA A FENNIE C | 1993 | J Clin Invest1993，92，： | 1 |
| 20 | Factors influencing pressure ulcer healing in adults over 50:an exploratory study显示文摘 | Jones K R Fennie K | 2007 | J Am Med Dir Assoc2007，8，6： | 1 |
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