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| 1 | Clinical benefits of biochemical markers of bone turnover in Egyptian children with chronic liver diseases显示文摘AIM: To investigate the association between serum insulin-like growth factor 1 (IGF-1), osteocalcin, and parathyroid hormone (PTH) levels with the etiology and clinical condition of patients with chronic liver disease.METHODS: Eighty children with hepatocellular damage were divided into 3 groups according to the etiology of disease infection: bilharziasis (9 patients), hepatitis B virus (HBV, 12 patients) and hepatitis C virus (HCV, 29 patients). The Child score index was found as A in 24 patients, B in 22 patients, C in 4 patients. Thirty healthy children served as control group. HBsAg, HBcAbIgM, HBcAbIgG, and anti-HCV were detected using ELISA technique. HCV-RNA was measured by reverse transcription polymerase chain reaction (RT-PCR). Anti-bilharzial antibodies were detected by indirect haem- agglutination test. Liver function tests were performed using autoanalyser. Serum IGF-1, osteocalcin and PTH levels were measured by ELISA technique. Abdominal ultrasonography was also conducted.RESULTS: Serum IGF-1 level was significantly lower in all patient groups with liver diseases, while serum osteocalcin and PTH levels were significantly elevated in patients with HBV and HCV infections compared with the control group. Serum osteocalcin and PTH concentrations were measured with the severity of liver disease from Child A to C. Child A patients unexpectedly showed significantly reduced IGF-1 levels in comparison to patients staged as Child B or C. Serum osteocalcin level was negatively correlated with albumin (14.7 ± 0.54 vs 3.6 ± 0.10, P < 0.05), while that for PTH was positivelycorrelated with total protein (70.1 ± 2.17 vs 6.7 ± 0.10, P < 0.05) in patients with HCV infection.CONCLUSION: Low serum IGF-1 level seems to play a critical role in the bone loss in patients with chronic liver disease. Elevated biochemical markers of bone remodeling suggest high-turnover in patients with viral infection and reflect severity of the clinical stage. | Karam A Mahdy Hanaa H Ahmed Fathia Mannaa Azza Abdel-Shaheed | 2007 | World Journal of Gastroenterology2007，13，5： | 3 |
| 2 | 吹填土热力固结和强度特性试验研究显示文摘揭示温度对吹填土固结和强度特性的影响,对合理评价热真空预压加固效果具有重要意义.通过自主研发的温控三轴仪,系统开展了吹填土的热力固结和强度试验研究.重点分析了不同温度下吹填土的排水体积、渗透系数、孔隙水压力和固结度的演化规律,研究了固结后吹填土在排水和不排水条件下有效应力路径和应力应变关系,提出了考虑不同温度的邓肯-张模型参数.结果表明,升温过程中,土体固结变形存在明显的三阶段特征:快速增加阶段、缓慢增加阶段和稳定阶段.排水量呈指数关系增长,渗透系数线性增长,孔隙水压力消散加快,固结度逐渐增大,吹填土排水与不排水抗剪强度均显著提高.不排水条件下CSL线斜率M值大于排水条件下M值.升温不排水条件下吹填土有效球应力p′值基本维持不变,升温排水条件下吹填土偏应力q随着球应力p线性增加.确定了不同温度条件下邓肯-张模型参数,提出升温不排水条件下,可采用邓肯-张模型来描述应力应变关系,但在升温排水条件下,可采用邓肯-张模型和线性模型综合反映应力应变关系. | 雷华阳 冯双喜 郝琪 张雅杰 Fathia Abdourazk ABDI | 2020 | 天津大学学报(自然科学与工程技术版)2020，53，1： | 2 |
| 3 | Two medical abortion regimens for late first-trimester termination of pregnancy: a prospective randomized trial 显示文摘 | Dalenda C Ines N Fathia B | 2010 | Contraception2010，81，4： | 1 |
| 4 | Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors显示文摘 | Salmon Hélène Franciszkiewicz Katarzyna Damotte Diane Dieu-Nosjean Marie-Caroline Validire Pierre Trautmann Alain Mami-Chouaib Fathia Donnadieu Emmanuel | 2012 | EN2012，，3： | 1 |
| 5 | A multiobjectiveoptimization algorithm to solve the part feeding problemin mixed-model assembly lines 显示文摘 | FATHIA M ALVAREZA M J RODR′IGUEZB V | 2014 | Mathematical Problems in Engineering2014，11，80： | 1 |
| 6 | Gastric carcinoid tumors in multiple endocrine neoplasia-1 patients with Zollinger-Ellison syndrome can be symptomatic, demonstrate aggressive growth, and require surgical treatment显示文摘 | Jeffrey A. Norton Marc L. Melcher Fathia Gibril Robert T. Jensen | 2004 | Surgery2004，，6： | 1 |
| 7 | A prospective analysis of the frequency, location, and curability of ectopic (nonpancreaticoduodenal, nonnodal) gastrinoma显示文摘 | Peter C Wu H.Richard Alexander David L Bartlett John L Doppman Douglas L Fraker Jeffrey A Norton Fathia Gibril Franz Fogt Robert T Jensen | 1997 | Surgery1997，，6： | 1 |
| 8 | Determinants of metastatic rate and survival in patients with zollinger-ellison syndrome: A prospective long-term study显示文摘 | H.Christian Weber David J. Venzon Jaw-Town Lin Vitaly A. Fishbein Murray Orbuch Doris B. Strader Fathia Gibril David C. Metz Douglas L. Fraker Jeffrey A. Norton Robert T. Jensen | 1995 | Gastroenterology1995，，6： | 1 |
| 9 | Two medical abortion regimens for late first trimester termination of pregnancy: a prospective randomized trial显示文摘 | Dalenda C Ines N Fathia B | 2010 | Contraception2010，81，4： | 1 |
| 10 | Two medical abortion regimensfor late first-trimester termination of pregnancy:a prospective ran-domized trial显示文摘 | Dalenda C Ines N Fathia B | 2010 | Contraception2010，81，4： | 1 |
| 11 | Two medical abortion regimens for late first-trimester termination of pregnancy: a prospective randomized trial显示文摘 | Dalenda C Ines N Fathia B | 2010 | Contraception2010，81，4： | 1 |
| 12 | Management and outcome of patients with sporadic gastrinoma arising in the duodenum显示文摘 | Theresa G.Zogakis Fathia Gibril Steven K.Libutti | | 0，，01： | 1 |
| 13 | Molluscicidal effectiveness of Luo-Wei,a novel plant-derived molluscicide,against Oncomelania hupensis,Biomphalaria alexandrina and Bulinus truncatus显示文摘Background:Control of snail intermediate hosts has been proved to be a fast and efficient approach for interrupting the transmission of schistosomiasis.Some plant extracts have shown obvious molluscicidal activity,and a new compound Luo-Wei,also named tea-seed distilled saponin(TDS),was developed based on the saponins extracted from Camellia oleifera seeds.We aimed to test the molluscicidal activity of 4%TDS against the intermediate host snails in China and Egypt,and evaluate its environmental safety to non-target organisms.Methods:In the laboratory,Oncomelania hupensis,Biomphalaria alexandrina and Bulinus truncatus were exposed to 4%TDS,and the median lethal concentration(LC5o)was estimated at 24,48 and 72 h.In the field,snail mortalities were assessed 1,2,3 and 7 d post-immersion with 2.5 g/m34%TDS and 1,3,7 and 15 d post-spraying with 5 g/m24%TDS.in addition,the acute toxicity of 4%TDS to Japanese quail(Coturnixjaponica),zebrafish(Brachydanio rerio)and freshwater shrimp(Macrobrachium nipponense)was assessed by estimations of LC5o or median lethal dose(LD5o).Results:In the laboratory,the LC5o values of 4%TDS for O.hupensis were 0.701,0.371 and 0.33 mg/L at 24,48 and 72 h,respectively,and 4%TDS showed a 0.33 mg/L 24 h LC5o against B.alexandrina,and a 1.396 mg/L 24 h LCs0 against B.truncatus.Across all study regions,the pooled mortalities of O.hupensis were 72,86,94 and 98%at 1,2,3 and 7 d,following field immersion of 4%TDS at a dose of 2.5 g/m3,and were 69,77,85 and 88%at 1,3,7 and 15 d,following field spraying at 5 g/m2,respectively.4%TDS had moderate toxicity to Japanese quail(7 d LD5o>60 mg/kg)and to shrimp(96 h LCs0=6.28 mg/L;95%CI:3.53-11.2 mg/L),whereas its toxicity to zebrafish was high(96 h LCso--0.15 mg/L;95%CI:0.14-0.17 mg/L).Conclusions:4%TDS is active against O.hupensis,B.alexandrina and B.truncatus under laboratory and field conditions,and it may be a candidate molluscicide of plant origin. | Tie-Wu Jia Wei Wang Le-Ping Sun Shan Lv Kun Yang Neng-Min Zhang Xi-Bao Huang Jian-Bing Liu Han-Cheng Liu Rui-Hua Liu Fathia A.Gawish Mohamed R.Habib Mohamed A.El-Emam Charles H.King Xiao-Nong Zhou | 2019 | Infectious Diseases of Poverty2019，8，2： | 1 |
| 14 | Water-in-oil Emulsion Liquid Membrane Transport of L-Cysteine显示文摘 | FATHIA S A M YAFTIANA M R KARGARIB A | 2013 | Separa Sci and Tech2013，48，1： | 1 |
| 15 | High -yielding,large -scale synthesis of N - protected - β- Aminonitriles : tert - butyl ( 1 R) i - 2 - cyano - 1 - phenylethylcarbamate 显示文摘 | Fathia M Carl T Michel V | 2008 | Organic Syntheses2008，85，： | 1 |
| 16 | Preparation and bioactivity evaluation of bone-like hydroxyapatite nanopowder 显示文摘 | Fathia M H Hanifia A Mortazavib V | 2008 | Journal of Materials Processing Technology2008，202，13： | 1 |
| 17 | Two medical abortion regimens for late first-trimester termination of pregnancy: a prospective randomized trial 显示文摘 | Dalenda C Ines N Fathia B | 2010 | Contraception2010，81，4： | 1 |
| 18 | Determinants of metastatic rate and survival in patients with zollinger-ellison syndrome: A prospective long-term study显示文摘 | H.Christian Weber David J. Venzon Jaw-Town Lin Vitaly A. Fishbein Murray Orbuch Doris B. Strader Fathia Gibril David C. Metz Douglas L. Fraker Jeffrey A. Norton Robert T. Jensen | 1995 | Gastroenterology1995，，6： | 1 |
| 19 | Does the Use of Routine Duodenotomy (DUODX) Affect Rate of Cure, Development of Liver Metastases, or Survival in Patients With Zollinger-Ellison Syndrome?显示文摘 | Jeffrey A. Norton H Richard Alexander Douglas L. Fraker David J. Venzon Fathia Gibril Robert T. Jensen | 2004 | Annals of Surgery2004，，5： | 1 |
| 20 | Two medical abortion regimens for late first-trimester termination of pregnancy:a prospective randomized trial显示文摘 | Dalenda C Ines N Fathia B | | 0，，04： | 1 |
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