维普中文期刊产品整合服务
10篇 您的检索式:作者名="Fareeda"
    题名 作者 年代 出处 被引量
1Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial显示文摘Tom Waddell Ian Chau David Cunningham David Gonzalez Alicia Frances Clare Okines Andrew Wotherspoon Claire Saffery Gary Middleton Jonathan Wadsley David Ferry Wasat Mansoor Tom Crosby Fareeda Coxon David Smith Justin Waters Timothy Iveson Stephen Falk Sar 2013Lancet Oncology2013,,6:10
2High Detection Rates of Colorectal Neoplasia by Stool DNA Testing With a Novel Digital Melt Curve Assay显示文摘Hongzhi Zou William R. Taylor Jonathan J. Harrington Fareeda Taher Nazer Hussain Xiaoming Cao Charles L. Loprinzi Theodore R. Levine Douglas K. Rex Dennis Ahnen Kandice L. Knigge Peter Lance Xuan Jiang David I. Smith David A. Ahlquist 2009Gastroenterology2009,,2:2
3Pharmacokinetic evaluation,molecular docking and in vitro biological evaluation of 1,3,4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors显示文摘1, 3, 4-Oxadiazole derivatives(4 a–5 f) were previously synthesized to investigate their anticancer properties.However, studies relating to their antioxidant potential and signal transducer and activator of transcription(STAT) inhibition have not been performed. We investigated previously synthesized 1, 3, 4-oxadiazole derivatives(4 a–5 f) for various radical scavenging properties using several in vitro antioxidant assays and also for direct inhibition of STAT3 through molecular docking. The data obtained from various antioxidant assays such as 2, 2,-diphenyl-1-picrylhydrazyl radical(DPPH), nitric oxide, hydrogen peroxide, and superoxide anion radical revealed that among all the derivatives, compound 5 e displayed high antioxidant activities than the standard antioxidant L-ascorbic acid. Additionally, the total reduction assay and antioxidant capacity assay further confirmed the antioxidant potential of compound 5 e. Furthermore, the molecular docking studies performed for all derivatives along with the standard inhibitor STX-0119 showed that binding energy released in direct binding with the SH2 domain of STAT3 was the highest for compound 5 e(-9.91 kcal/mol).Through virtual screening, compound 5 e was found to exhibit optimum competency in inhibiting STAT3 activity. Compound 5 e decreased the activation of STAT3 as observed with Western blot. In brief, compound5 e was identified as a potent antioxidant agent and STAT3 inhibitor and effective agent for cancer treatment.Rashmin khanam Iram I.Hejazi Syed Shahabuddin Abdul R.Bhat Fareeda Athar 2019Journal of Pharmaceutical Analysis2019,9,2:1
4Synthesis, characterization and anticancer screening of some novel piperonyl–tetrazole derivatives显示文摘Mohammad Arshad Abdul Roouf Bhat Smritee Pokharel Ji-Eun Kim Eun Ju Lee Fareeda Athar Inho Choi 2014European Journal of Medicinal Chemistry2014,,:1
5Cyclootadiene Ru(Ⅱ) complexes of thiophene-2-carboxaldehyde-derived thiosemicarbazones:Synthesis,characterization and antiamoebic activity显示文摘Shailendra Singh Fareeda Athar Mannar R Maurya 2006European Journal of Medicinal Chemistry2006,41,:1
63-(1,3,4-Thiadiazole-2-yl)quinoline derivatives: Synthesis, characterization and anti-microbial activity显示文摘Abdul R. Bhat Tazeem Amir Azam Inho Choi Fareeda Athar 2011European Journal of Medicinal Chemistry2011,,7:1
7T2036 Pan-Detection of Gastrointestinal Neoplasms By Stool DNA Testing: Establishment of Feasibility显示文摘Hongzhi Zou Jonathan J. Harrington William R. Taylor Mary E. Devens Xiaoming Cao Russell I. Heigh Yvonne Romero Suresh T. Chari Gloria M. Petersen Lewis R. Roberts Jan Kasperbauer Fareeda T. Hussain Julie A. Simonson David I. Smith David A. Ahlquist 2009Gastroenterology2009,,5:1
8Sole abnormalities of chromosome 7 in myeloid malignancies: Spectrum, histopathologic correlates, and prognostic implications显示文摘Fareeda Taher Nazer Hussain Edward P. Nguyen Sania Raza Ryan Knudson Animesh Pardanani Curtis A. Hanson Daniel Van Dyke Ayalew Tefferi 2012Am J Hematol2012,,7:1
9色彩与创意才是主宰显示文摘这套位丁孟买的复式公寓面朝大海,视师开闲经由MOS(Multitude orSins)设计团队精心改造之后,展现出怪趣的艺术氛围,彰显精致考究的装饰风格。Ishita Sitwala(摄影) Fareeda Kanga Ecao Gu 唐能(翻译) 2022家居廊2022,,12:0
10Synthesis,characterization and antibacterial screening of some novel 1,2,4-triazine derivatives显示文摘A new series of 1, 2, 4-triazine derivatives possessing indole nucleus were synthesized with an aim to explore their effect on in vitro growth of microorganisms causing microbial infection. In vitro antimicrobial activity was performed against S. aureus, S. epidermidis, P. mirabilis and E. coli using disk diffusion method. The MIC was detected using the double dilution method. The results were compared by calculating percent inhibition area/mg of the compounds with the standard drug 'Ciprofloxacin'.Selected compounds were evaluated for toxic effects using human hepatocellular carcinoma(HepG2) cell line by MTT-assay. Results revealed that some compounds of the series were found to exhibit better activity with less toxicity thanMohammad Arshad Abdul Roouf Bhat Kwon Kang Hoi Inho Choi Fareeda Athar 2017Chinese Chemical Letters2017,28,7:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费