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    题名 作者 年代 出处 被引量
1Metabolic profiling analysis of a D-galactosamine/lipopolysaccharide- induced mouse model of fulminant hepatic failure显示文摘Feng, B Wu, SM Lv, S Liu, F Chen, HS Yan, XZ Li, Y Dong, FT Wei, L 2007中国生物学文摘2007,21,11:23
2Identification of tumor associated single-chain Fv by panning and screening antibody phage library using tumor cells显示文摘AIM:To study the feasibility of panning and screeningphage-displaying recombinant single-chain variablefragment (ScFv) of anti-tumor monoclonal antibodiesfor fixed whole cells as the carriers of mAb-bindingantigens.ME,ODS: The recombinant phage displaying librariesfor anti-colorectal tumor mAb MC3Ab, MC5Ab andanti-gastric tumor mAb MGD1 was constructed.Panning and screening were carried outby means ofmodified fixation of colorectal and gastric tumor cellsexpressed the mAb-binding antigens. Concordance ofbinding specificity to tumor cells between phageclones and parent antibodies was analyzed. Thephage of positive clones was identified withcompetitive ELISA, and infected by E.coli HB2151 toexpress soluble ScFv.RESULTS:The ratio of positive clones to MC3-ScF-MC5-ScFv and MGD1-ScFv were 60 %, 24 % and 30 %. MC3-ScFv had Mr 32 000 confirmed by Western blot. Thespecificity to antigen had no difference between 4positive recombinant phage antibodies and MC3Ab.CONCLUSION:The modified process of fixing wholetumor cells is efficient, convenient and feasible to panand screen the phage-displaying ScFv of anti-tumormonoclonal antibodies.Nie, YZ He, FT Li, ZK Wu, KC Cao, YX Chen, BJ Fan, DM 2002World Journal of Gastroenterology2002,8,4:12
3围术期大剂量阿托伐他汀疗法能够减少心脏手术后的急性肾损伤吗?显示文摘他汀类药物能够影响急性肾损伤(AKI)的几个环节。为了验证假说:围术期短期大剂量阿托伐他汀能够减少心脏手术后发生AKI,美国学者从2009年11月到2014年10月在范德比尔特大学医学中心进行了成人心脏手术患者的双盲、安慰剂对照的随机临床试验。Billings FT 4th Hendricks PA Schildcrout JS 王建中 2016中华肾病研究电子杂志2016,5,1:9
4The Latent Structure of Medically Unexplained Symptoms and Its Relation to Functional Somatic Syndromes显示文摘Michael Witth?ft Wolfgang Hiller Noelle Loch Fabian Jasper 2013International Journal of Behavioral Medicine2013,,2:2
5The endoscopic assessment of esophagitis: A progress report on observer agreement显示文摘D Armstrong JR Bennett AL Blum J Dent FT De Dombal JP Galmiche L Lundell M Margulies JE Richter SJ Spechler GN Tytgat L Wallin 1996Gastroenterology1996,,1:2
6Adaptive Sliding Mode Control for MIMO Nonlinear Systems Based on Fuzzy Logic Scheme显示文摘In this study an indirect adaptive sliding mode control (SMC) based on a fuzzy logic scheme is proposed to strengthen the tracking control performance of a general class of multi-input multi-output (MIMO) nonlinear uncertain systems. Combining reaching law approach and fuzzy universal approximation theorem, the proposed design procedure combines the advantages of fuzzy logic control, adaptive control and sliding mode control. The stability of the control systems is proved in the sense of the Lyapunov second stability theorem. Two simulation studies are presented to demonstrate the effectiveness of our new hybrid control algorithm.Alan FT Winfield Chris Melhuish 2004International Journal of Automation and computing2004,1,1:2
7Cloning and identification of an angiostatic molecule IP-10/crg-2显示文摘AIM To obtain human and murine cDNAsencoding IFN--y inducible protein 10 (lP--10) andcytokine responsive gene--2 (Crg-2).METHODS The encoding genes of lP-10 and Crg2 were amplified by RT--PCR from Cultured humanfibroblast cells and Balb/ c mouse liver treatedby IFN-y and TNF-a, respectively, and clonedinto plasmids of PUC19 and PGEM3Zf(+ ).RESULTS The nucleotide sequences ot theamplified DNA were confirmed by endonucleasesdigestion and sequencing.CONCLUSION Recombinant lP-10/ crg--2 geneclones with 306 hp and 314 hp inserts wereestablished for further research on biologicalactivities and ligands of hiP-10/mCrg--2.Liu ZG Yang JH An HZ Wang HY He FT Han ZY Han Y Wu HP Xiao B Fan DM 1999World Journal of Gastroenterology1999,5,3:2
8New quantitative and qualitative measures on functional mobility prediction for stroke patients显示文摘Lee MY Wong MK Tang FT 1998J Med Eng Technol1998,22,1:2
9Geneticmodification of liver grafts with an adenoviral vector encoding the Bcl-2 geneimproves organ preservation显示文摘Bilbao G Contreras JL Gomez Navarro J Eckhoff DE Mikheeva G Krasnykh V Hynes T Thomas FT Thomas JM Curiel DT 0,,:2
10胎盘生长因子抑制胎盘缺血引起的高血压显示文摘先兆子痫最有效的治疗是提前分娩出胎儿和胎盘。胎盘缺血的发生对先兆子痫发病有至关重要的影响,因为在动物或人类,子宫灌注压减少(reduced uterine perfusion pressure,RUPP)可诱发胎盘缺血/缺氧,刺激机体释放高血压胎盘因子进入母体循环。抗血管生成因子可溶性fms样酪氨酸激酶1(soluble fms-like tyrosine kinase-1,sFlt-1)可拮抗和减少有生物活性的血管内皮生长因子( vascular endothelial growth factor, VEGF)和胎盘生长因子( placental growth factor, PIGF),研究发现在RUPP大鼠和先兆子痫患者中,sFlt-1水平升高。刘莉 叶鹏 Spradley FT Tan AY Joo WS Daniels G Kussie P Karumanchi SA Granger JP 2016中华高血压杂志2016,24,2:2
11Laparoscopic left lateral resection is the gold standard for benign liver lesions: a case–control study显示文摘Safi Dokmak Vikram Raut Béatrice Aussilhou Fadhel Samir Ftériche Olivier Farges Alain Sauvanet Jacques Belghiti 2014HPB2014,,2:2
12A modified labeling theory approach to mental disorders:An empirical assessment显示文摘Link BG Cunen FT Struening EL 1989American Sociological Review1989,54,:1
13Control of rubella and congenital rubella syndrome (CRS) in developing countries,pard:burden of disease from CRS 显示文摘Cutts FT Robertson SE Diaz-Ortega JL 1997Bull World Health Organ1997,75,1:1
14Human papillomavirus and HPV vaccines:a review显示文摘Cutts FT Franceschi S Goldie S 2007Bulletin of the World Health Organization2007,85,:1
15Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid-a role in periodontal inflammation显示文摘 Salmon AL Lamey PJ 2000J Clin Periodontol2000,27,7:1
16Clinical presentation of acute abdomen:study of 600 patients显示文摘 Ditchburn J de Dombal FT 1972Br Med1972,3,5823:1
17Microstructure and formation mechanism of in situ synthesized TiC/Ti surface MMC on Ti-6Al-4V by laser cladding显示文摘 Zhang S Cheng FT 2001Scripta Materialia2001,,44:1
18Right ventricular dysfunction and pulmonary valve replacement after correction of tetralogy of Fallot显示文摘Ruijter FT Weenink I Hitchcock FJ 2002Ann thorac Surg2002,73,6:1
19The superficial temporal artery trunk as a donor vessel in cerebral revascularization:benefits and pitfalls显示文摘Alaraj A Ashley WW Jr Charbel FT 2008Neurosurg Focus2008,24,:1
20IL-1 receptor-associated kinase and low molecular weight GTPase RhoA signal molecules are required for bacterial lipopolysaccharide-induced cytokine gene transcription显示文摘Chen LY Zuraw BL Liu FT 2002J Immunol2002,169,7:1
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