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| 1 | Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and a major cause of cancer-related mortality for which liver resection is an important curative-intent treatment option. However, many patients present with advanced disease and with underlying chronic liver disease and/or cirrhosis, limiting the proportion of patients who are surgical candidates. In addition, the development of recurrent or de novo cancers following surgical resection is common. These issues have led investigators to evaluate the benefit of neoadjuvant and adjuvant treatment strategies aimed at improving resectability rates and decreasing recurrence rates. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. In this review, we evaluate the evidence for various neoadjuvant and adjuvant therapies and discuss opportunities for future clinical and translational research. | Clifford Akateh Sylvester M Black Lanla Conteh Eric D Miller Anne Noonan Eric Elliott Timothy M Pawlik Allan Tsung Jordan M Cloyd | 2019 | World Journal of Gastroenterology2019，25，28： | 16 |
| 2 | Hepatocellular carcinoma locoregional therapies:Outcomes and future horizons显示文摘Hepatocellular carcinoma(HCC)is the most common primary cancer of the liver and has an overall five-year survival rate of less than twenty percent.For patients with unresectable disease,evolving liver-directed locoregional therapies provide efficacious treatment across the spectrum of disease stages and via a variety of catheter-directed and percutaneous techniques.Goals of locoregional therapies in HCC may include curative intent in early-stage disease,bridging or downstaging to surgical resection or transplantation for early or intermediate-stage disease,and local disease control and palliation in advanced-stage disease.This review explores the outcomes of chemoembolization,bland embolization,radioembolization,and percutaneous ablative therapies.Attention is also given to prognostic factors related to each of the respective techniques,as well as future directions of locoregional therapies for HCC. | Mina S Makary Stuart Ramsell Eric Miller Eliza W Beal Joshua D Dowell | 2021 | World Journal of Gastroenterology2021，27，43： | 2 |
| 3 | Iris manipulation during phacoemulsification:intraoperative and postoperative complications显示文摘AIM:To quantify intraoperative and postoperative complications in complex phacoemulsification cataract extraction(phacoemulsification)with iris manipulation compared to non-complex and complex phacoemulsification without iris manipulation.METHODS:All phacoemulsification cases at the University of Colorado between January 1,2014,and June 30,2017 were included.Exclusion criteria for the primary outcome of intraoperative complications were planned combination surgery and eyes with less than 28 d followup.Exclusion criteria for the secondary outcomes of postoperative complications were unplanned additional surgery,and chronic steroid eye drop use prior to surgery.Data including sex,race/ethnicity,surgery length,visual acuity,intraoperative and postoperative complications,and intraocular pressures(IOP)were collected and analyzed utilizing general linear and Logistic regression modeling.RESULTS:The medical records of 5772 eyes were reviewed(500 complex without iris manipulation,367 with iris manipulation).The number of any intraoperative complication in the complex with iris manipulation and complex without iris manipulation groups was 15(4.1%)and 26(5.2%),respectively,compared to 41(0.8%)in the non-complex group.Postoperative inflammation was found in 135(2.8%)non-complex cases,20(4.1%)complex cases without iris manipulation,and 20(5.6%)complex cases with iris manipulation.The adjusted odds ratio of postoperative inflammation in phacoemulsification with iris manipulation compared to non-complex was 2.3(95%CI:1.3-4.0,P=0.005).The rate of IOP spikes>10 mm Hg was significantly greater in cases with iris manipulation(P=0.001).CONCLUSION:Complex cases have more intraoperative complications.However,only complex cases with iris manipulation led to increase rates of postoperative inflammation and IOP spikes>10 mm Hg. | Eric R.Williams Jennifer L.Patnaik D.Claire Miller Anne M.Lynch Richard S.Davidson Malik Y.Kahook Leonard K.Seibold | 2021 | International Journal of Ophthalmology(English edition)2021，14，5： | 2 |
| 4 | A MyD88-dependent IFNyR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge显示文摘 | Eric M Pietras Lloyd S Miller Carl T Johnson Ryan M O'Connell Paul W Dempsey Genhong Cheng | 2011 | Cell Research2011，21，7： | 2 |
| 5 | Characterization of Hepatitis C Virus Resistance from a Multiple-Dose Clinical Trial of the Novel NS5A Inhibitor GS-5885显示文摘 | Kelly A. Wong Angela Worth Ross Martin Evguenia Svarovskaia Diana M. Brainard Eric Lawitz Michael D. Miller Hongmei Mo | 2013 | Antimicrobial Agents and Chemotherapy2013，，12： | 2 |
| 6 | Mercury Concentrations in Bicknell’s Thrush and Other Insectivorous Passerines in Montane Forests of Northeastern North America显示文摘 | Christopher C. Rimmer Kent P. McFarland David C. Evers Eric K. Miller Yves Aubry Daniel Busby Robert J. Taylor | 2005 | Ecotoxicology (-)2005，，1： | 1 |
| 7 | Microstructure and mechanical properties of titanium componentsfabricated by a new powder injection molding technique 显示文摘 | Eric Nyberg Megan Miller Kevin Simmons | 2005 | Materials Science and Engineering2005，25，2005： | 1 |
| 8 | Microstructure and mechanical properties of titanium components fabricated by a new powder injection moulding technique显示文摘 | Eric Nyberg Megan Miller Kevin Simmons | 2005 | Materials Science and Engineering C2005，，25： | 1 |
| 9 | Impact of Obesity on Cardiovascular Disease显示文摘 | Kerstyn C. Zalesin Barry A. Franklin Wendy M. Miller Eric D. Peterson Peter A. McCullough | 2011 | Medical Clinics of North America2011，，5： | 1 |
| 10 | Teaching and physics education research: bridging the gap显示文摘 | James M Fraser Anneke L Timan Kelly Miller Jason E Dowd Laura Tucker Eric Mazur | 2014 | Reports on Progress in Physics2014，，3： | 1 |
| 11 | Factors Influencing the Performance of Springboard Dives of Increasing Sifficulty显示文摘 | DORIS I MILLER ERIC J SPRIGINGS | 2001 | J Applied Biomech2001，，17： | 1 |
| 12 | Multiobjective approach to long-term interurban muhilevel road network planning 显示文摘 | Bruno Santos Antonio Antunes Eric Miller | 2009 | Journal of Transportation Engineering2009，135，9： | 1 |
| 13 | Effect of Prasugrel Pre-Treatment Strategy in Patients Undergoing Percutaneous Coronary Intervention for NSTEMI显示文摘 | Gilles Montalescot Jean-Philippe Collet Patrick Ecollan Leonardo Bolognese Jurrien ten Berg Dariusz Dudek Christian Hamm Petr Widimsky Jean-Fran?ois Tanguay Patrick Goldstein Eileen Brown Debra L. Miller LeRoy LeNarz Eric Vicaut | 2014 | Journal of the American College of Cardiology2014，，： | 1 |
| 14 | Validation of TASHA: a 24-h activity scheduling microsimulation model 显示文摘 | Roorda Matthew J Miller Eric J Habib Khandker M N | 2008 | Transportation Research Part A2008，42，2： | 1 |
| 15 | Usefulness of Two-Dimensional Speckle Strain for Evaluation of Left Ventricular Diastolic Deformation in Patients With Coronary Artery Disease显示文摘 | Hsin-Yueh Liang Sanderson Cauduro Patricia Pellikka Jianwen Wang Stig Urheim Eric H. Yang Chiranjit Rihal Marek Belohlavek Bijoy Khandheria Fletcher A. Miller Theodore P. Abraham | 2006 | The American Journal of Cardiology2006，，12： | 1 |
| 16 | Wavelet domain image restoration with adaptive edge-preserving regularization显示文摘 | Belge Murat Kilmer Misha E Miller Eric L | 2000 | IEEE Transaction on Image Processing2000，9，4： | 1 |
| 17 | Integrating an Activity-Based Travel Demand Model with Dynamic Traffic Assignment and Emission Models: Implementation in the Greater l'oronto, Canada, Area显示文摘 | Hao Jiangyang Hatzopoulou Marianne Miller Eric I | 2010 | Transportation Research Record: Journal of the Transportation Research Board2010，，2176： | 1 |
| 18 | ILUTE: an operational prototype of a comprehensive micro-simulation model of urban systems 显示文摘 | SALVINI P ERIC J MILLER E J | 2005 | Networks and Spatial Economics2005，5，： | 1 |
| 19 | Integrating applications on the semantic web显示文摘 | Tim Berners-Lee Eric Miller | 2002 | Journal of the Institute of Electrical Engineers of Japan2002，122，10： | 1 |
| 20 | Transportation land-use interaction:empirical findings in North America,and their implications for modeling显示文摘 | Daniel A Badoe Eric J Miller | 2000 | Transportation Research D:Transport & Environment2000，5，4： | 1 |
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