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446篇 您的检索式:作者名="Busby"
    题名 作者 年代 出处 被引量
1Emulation of neutron irradiation effects with protons: validation of principle显示文摘G.S Was J.T Busby T Allen E.A Kenik A Jensson S.M Bruemmer J Gan A.D Edwards P.M Scott P.L Andreson 2002Journal of Nuclear Materials2002,,2:2
2Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit显示文摘Robert W. Busby Alexander P. Bryant Wilmin P. Bartolini Etchell A. Cordero Gerhard Hannig Marco M. Kessler Shalina Mahajan-Miklos Christine M. Pierce Robert M. Solinga Li Jing Sun Jenny V. Tobin Caroline B. Kurtz Mark G. Currie 2010European Journal of Pharmacology2010,,1:2
3Formation mechanisms of sub-micron pharmaceutical composite particles derived from far-and near-field Raman microscopy显示文摘Surface enhanced Raman spectroscopy(SERS) and confocal Raman microscopy are applied to investigate the structure and the molecular arrangement of sub-micron furosemide and polyvinylpyrrolidone(furosemide/PVP) particles produced by spray flash evaporation(SFE). Morphology, size and crystallinity of furosemide/PVP particles are analyzed by scanning electron microscopy(SEM) and X-ray powder diffraction(XRPD). Far-field Raman spectra and confocal far-field Raman maps of furosemide/PVP particles are interpreted based on the far-field Raman spectra of pure furosemide and PVP precursors.Confocal far-field Raman microscopy shows that furosemide/PVP particles feature an intermixture of furosemide and PVP molecules at the sub-micron scale. SERS and surface-enhanced confocal Raman microscopy(SECo RM) are performed on furosemide, PVP and furosemide/PVP composite particles sputtered with silver(40 nm). SERS and SECo RM maps reveal that furosemide/PVP particle surfaces mainly consist of PVP molecules. The combination of surface and bulk sensitive analyses reveal that furosemide/PVP sub-micron particles are formed by the agglomeration of primary furosemide nanocrystals embedded in a thin PVP matrix. Interestingly, both far-field Raman microscopy and SECo RM provide molecular information on a statistically-relevant amount of sub-micron particles in a single microscopic map;this combination is thus an effective and time-saving tool for investigating organic sub-micron composites.Jakob Hübner Jean-Baptiste Coty Yan Busby Denis Spitzer 2021Journal of Pharmaceutical Analysis2021,11,4:2
4Volcanic facies architecture of an intra-arc strike-slip basin,Santa Rita Mountains,Southern Arizona显示文摘Busby C J Bassett K N 2007Bull Volcanol2007,69,:1
5The transition from tourism on farms to farm tourism显示文摘Busby G Rendle S 2000Tourism Management2000,21,6:1
6Identification and Analysis of Extended -10 Promoters in Escherichia coli 显示文摘Mitchell J Zheng D L Busby S 2003Nucleic Acids Research2003,31,16:1
7Human fibroblasts secrete a serine protease that cleaves insulin - like growth factor binding protein - 5 显示文摘Nam TJ Busby WH Clemmons DR 1994Endocrinology1994,135,4:1
8Mercury Concentrations in Bicknell’s Thrush and Other Insectivorous Passerines in Montane Forests of Northeastern North America显示文摘Christopher C. Rimmer Kent P. McFarland David C. Evers Eric K. Miller Yves Aubry Daniel Busby Robert J. Taylor 2005Ecotoxicology (-)2005,,1:1
9Chemoprevention for bladder cancer 显示文摘BUSBY JE KAMAT AM 2006J Urol2006,176,:1
10Linaclotide is a potent and selective gnanylate cyclase C agonist that elicitsphannacolog- ical effects locally in the gastrointestinal tract显示文摘Bryant AP Busby RW Bartolini WP 2010Life Sci2010,86,1920:1
11Identification and analysis of extended - 10 promoters in Escherichia coli显示文摘Mitchell J Zheng D Busby S 2003Nucleic Acids Research2003,31,16:1
12Fish Hepatocyte Phosphorylase-a Sensitive Indicator for Hormonal Modulation显示文摘Moon W T Busby G A Cooper D A 1999Fish Physiology Biochemistry1999,21,:1
13Pulmonary embolism in the clderly, 显示文摘Busby W Bayer A Pathy J 1988Age Ageing1988,17,3:1
14Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin显示文摘Sarkaria JN Tibbetts RS Busby EC 0,,:1
15Therapy of muhidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells 显示文摘Busby JE Kim S J Yazici S 2006Prostate2006,6,16:1
16Identification of the forms of insulin - like growth factor binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion 显示文摘Camacho - Hubner C Busby WH Mocusker RH 1992J Biol Chem1992,267,11:1
17BIOCLIMa bioclimate analysis and prediction system显示文摘Busby JR 1991 1991Plant Protection Quarterly1991,6,1:1
18Biological and physical properties of fibronectin pasteurized in the presence of stabilizers 显示文摘Miekka SI Busby TF Tarshis L 1985Vox Sang1985,48,5:1
19The regulation of bacterial transcription initiation显示文摘Browning D F Busby S J 2004Nature Bey Microbiol2004,2,:1
20MM-419447 is an active in vvivo metabolite of linaclotide,a therapeutic agent in development for the treatment of IBS-C and chronic constipation 显示文摘Busby Pt Bryant A Bartolini W 2006Drug Metab Rev2006,38,2:1
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