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| 1 | Effect of sedative agent selection on morbidity, mortality and length of stay in patients with increase in intracranial pressure显示文摘BACKGROUND: To identify the effects of sedative agent selection on morbidity, mortality, and length of stay in patients with suspected increase in intracranial pressure. Recent trends and developments have resulted in changes to medications that were previously utilized as pharmacological adjuncts in the sedation and intubation of patients with suspected increases in intracranial pressure. Medications that were previously considered contraindicated are now being used with increasing regularity without demonstrated safety and effectiveness. The primary objective of this study is to evaluate and compare the use of Ketamine as an induction agent for patients with increased intracranial pressure. The secondary objective was to evaluate and compare the use of Etomidate, Midazolam, and Ketamine in patients with increased intracranial pressure. METHODS: We conducted a retrospective chart review of patients transported to our facility with evidence of intracranial hypertension that were intubated before trauma center arrival. Patients were identifi ed during a 22-month period from January 2014 to October 2015. Goals were to evaluate the impact of sedative agent selection on morbidity, mortality, and length of stay.RESULTS: During the review 148 patients were identifi ed as meeting inclusion criteria, 52 were excluded due to incomplete data. Of those the patients primarily received; Etomidate, Ketamine, and Midazolam. Patients in the Ketamine group were found to have a lower mortality rate after injury stratifi cation. CONCLUSION: Patients with intracranial hypertension should not be excluded from receiving Ketamine during intubation out of concern for worsening outcomes. | Brian G.Cornelius Elizabeth Webb Angela Cornelius Kenneth W.G.Smith Srdan Ristic Jay Jain Urska Cvek Marjan Trutschl | 2018 | World Journal of Emergency Medicine2018，9，4： | 4 |
| 2 | Securitization and Risk: Empirical Evidence on US Danks' 显示文摘 | Hatice Uzun Elizabeth Webb | 2007 | The Journal of Risk Finance2007，8，1： | 1 |
| 3 | Corporate Social Responsibility and Financial Performance :The 'Virtuous Cir- cle 'Revisited显示文摘 | Nelling Edward Webb Elizabeth | 2009 | Rev Quant Finan Acc2009，32，： | 1 |
| 4 | Using statistics and mathematical modelling to understand infectious disease outbreaks:COVID-19 as an example显示文摘During an infectious disease outbreak,biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy.Motivated by the ongoing response to COVID-19,we provide a toolkit of statistical and mathematical models beyond the simple SIR-type differential equation models for analysing the early stages of an outbreak and assessing interventions.In particular,we focus on parameter estimation in the presence of known biases in the data,and the effect of non-pharmaceutical interventions in enclosed subpopulations,such as households and care homes.We illustrate these methods by applying them to the COVID-19 pandemic. | Christopher E.Overton Helena B.Stage Shazaad Ahmad Jacob Curran-Sebastian Paul Dark Rajenki Das Elizabeth Fearon Timothy Felton Martyn Fyles Nick Gent Ian Hall Thomas House Hugo Lewkowicz Xiaoxi Pang Lorenzo Pellis Robert Sawko Andrew Ustianowski Bindu Vekaria Luke Webb | 2020 | Infectious Disease Modelling2020，5，1： | 1 |
| 5 | Corporate social responsibility and financial performance: the “virtuous circle” revisited显示文摘 | Edward Nelling Elizabeth Webb | 2009 | Review of Quantitative Finance and Accounting2009，，2： | 1 |
| 6 | Regulator Scrutiny and Bank CEO Incentives显示文摘 | Elizabeth Webb | 2008 | Journal of Financial Services Research2008，，1： | 1 |
| 7 | Cardiac avoidance in breast radiotherapy: a comparison of simple shielding techniques with intensity-modulated radiotherapy显示文摘 | David Landau Elizabeth J. Adams Steve Webb Gillian Ross | 2001 | Radiotherapy and Oncology2001，，3： | 1 |
| 8 | Corporate SocialResponsibility and Financial Performance: The “VirtuousCircle” Revisited显示文摘 | EdwardNelling Elizabeth Webb | 2009 | Original Research2009，，32： | 1 |
| 9 | Genetic Basis for Congenital Heart Defects: Current Knowledge: A Scientific Statement From the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young显示文摘 | Mary Ella Pierpont Craig T. Basson D Woodrow Benson Bruce D. Gelb Therese M. Giglia Elizabeth Goldmuntz Glenn McGee Craig A. Sable Deepak Srivastava Catherine L. Webb | 2007 | Circulation2007，，23： | 1 |
| 10 | Sarbanes-Oxley compliance and violation: an empirical study 显示文摘 | Elizabeth Webb | 2008 | Review of Accounting and Finance2008，7，1： | 1 |
| 11 | Corporate social responsibility and financial performance: the “virtuous circle” revisited显示文摘 | Edward Nelling Elizabeth Webb | | 0，，： | 1 |
| 12 | Regulator Scrutiny and Bank CEO Incenfives 显示文摘 | Elizabeth Webb | 2008 | Journal of Financial Services Research2008，，33： | 1 |
| 13 | Hepatitis E virus: Western Cape, South Africa显示文摘AIM To conduct a prospective assessment of anti-hepatitis E virus(HEV) Ig G seroprevalence in the Western Cape Province of South Africa in conjunction with evaluating risk factors for exposure.METHODS Consenting participants attending clinics and wards of Groote Schuur, Red Cross Children's Hospital and their affiliated teaching hospitals in Cape Town, South Africa, were sampled. Healthy adults attending blood donor clinics were also recruited. Patients with known liver disease were excluded and all major ethnic/race groups were included to broadly represent local demographics. Relevant demographic data was captured at the time of sampling using an interviewer-administered confidential questionnaire. Human immunodeficiency virus(HIV) status was self-disclosed. HEV Ig G testing was performed using the Wantai? assay.RESULTS HEV is endemic in the region with a seroprevalence of 27.9%(n = 324/1161) 95%CI: 25.3%-30.5%(21.9% when age-adjusted) with no significant differences between ethnic groups or HIV status. Seroprevalence in children is low but rapidly increases in early adulthood. With univariate analysis, age ≥ 30 years old, pork and bacon/ham consumption suggested risk. In the multivariate analysis, the highest risk factor for HEV Ig G seropositivity(OR = 7.679, 95%CI: 5.38-10.96, P < 0.001) was being 30 years or older followed by pork consumption(OR = 2.052, 95%CI: 1.39-3.03, P < 0.001). A recent clinical case demonstrates that HEV genotype 3 may be currently circulating in the Western Cape.CONCLUSION Hepatitis E seroprevalence was considerably higher than previously thought suggesting that hepatitis E warrants consideration in any patient presenting with an unexplained hepatitis in the Western Cape, irrespective of travel history, age or ethnicity. | Richie G Madden Sebastian Wallace Mark Sonderup Stephen Korsman Tawanda Chivese Bronwyn Gavine Aniefiok Edem Roxy Govender Nathan English Christy Kaiyamo Odelia Lutchman Annemiek A van der Eijk Suzan D Pas Glynn W Webb Joanne Palmer Elizabeth Goddard Sean Wasserman Harry R Dalton C Wendy Spearman | 2016 | World Journal of Gastroenterology2016，22，44： | 0 |
| 14 | Compression Therapy to Prevent Recurrent Cellulitis of the Leg显示文摘Background:Chronic edema of the leg is a risk factor for cellulitis.Daily use of compression garments on the leg has been recommended to prevent the recurrence of cellulitis,but there is limited evidence from trials regarding its effectiveness.Methods:In this single-center,randomized,nonblinded trial,we assigned participants with chronic edema of the leg and recurrent cellulitis,in a 1:1 ratio,to receive leg compression therapy plus education on cellulitis prevention(compression group)or education alone(control group).Follow-up occurred every 6 months for up to 3 years or until 45 episodes of cellulitis had occurred in the trial.The primary outcome was the recurrence of cellulitis. | Elizabeth Webb | 2021 | 四川生理科学杂志2021，43，1： | 0 |
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