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| 1 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 2 | Burden of deep vein thrombosis in the outpatient setting following major orthopedic surgery显示文摘 | Edith A Nutescu Andrew F Shorr | 2008 | J Bone Joint Surg(Am)2008，，： | 1 |
| 3 | Comparison of various tetraalkyl ammonium salts as supporting electrolytes in organic electrochemical reactions显示文摘 | Herbert O H Edith F Norton P P | 1971 | J Org Chem1971，36，： | 1 |
| 4 | Retinal Vascular Development Is Mediated by Endothelial Filopodia, a Preexisting Astrocytic Template and Specific R-Cadherin Adhesion显示文摘 | Michael ID Edith A Martin F | 2002 | Investigative Ophthalmology and Visual Science2002，43，： | 1 |
| 5 | Complement activation and protein adsorption by carbon nanotubes 显示文摘 | Carolina S M Emmanuel F Edith S | 2006 | Molecular Immunology2006，43，3： | 1 |
| 6 | Comparison of Various Tetraalkylammonium Salts as Supporting Electrolytes in Organic Electrochemical Reactions 显示文摘 | Herbert O H Edith F Norton P P | 1971 | J Org Chem1971，36，： | 1 |
| 7 | Incidental findings on integrated PET/CT that do not accumulate ^18F-FDG 显示文摘 | John F Mylene T Edith M | 2006 | AIR2006，187，： | 1 |
| 8 | The study ofmechanical properties of Sn-Ag-Cu lead-free solders withdifferent Ag contents and Ni doping under different strain ratesand temperatures 显示文摘 | Che F X Zhu W H Edith S W | 2010 | Journal of Alloys and Compounds2010，507，1： | 1 |
| 9 | Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits显示文摘 | Scheppke Lea Aguilar Edith Gariano Ray F Jacobson Ruth Hood John Doukas John Cao Jon Noronha Glenn Yee Shiyin Weis Sara Martin Michael B Soll Richard Cheresh David A Friedlander Martin | 2008 | Journal of Clinical Investigation2008，，6： | 1 |
| 10 | Complement activation and protein adsorption by carbon nanotubes 显示文摘 | Carolina S M Emmanuel F Edith S | 2006 | Molecular Immunology2006，43，3： | 1 |
| 11 | Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study显示文摘 | CLAUDIA M O MARGA C O EDITH J M F | 2001 | Lancet2001，357，： | 1 |
| 12 | Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction显示文摘 | Boekholdt SM Mieke T Ron JP Marc E Jolanda B Edith F | 2002 | Arterioscler Thromb Vasc Biol2002，22，12： | 1 |
| 13 | An Analysis of transfusion practice and the role of intraoperative red blood cell salvage during cesarean delivery显示文摘 | Jill F Edith D Hey J K | 2007 | Anesth Analg2007，104，： | 1 |
| 14 | Self-assessed physical and mental function of hameodialysis patients显示文摘 | Sanjeev KM Lori A Edith F | 2001 | Nephrol Dial Transplant2001，16，7： | 1 |
| 15 | Colonization of Arabidopsis Roots by Trichoderrna atroviride Promotes Growth and Enhances Systemic Disease Resistance Through Jasmonic Acid/Ethylene and Salicylic Acid Pathways显示文摘 | MIGUEL A S M MIGUEL A S F EDITH E U R | 2011 | Eur J Plant Pathol2011，131，： | 1 |
| 16 | Antimicrobial lipids:Emerging effector molecules of innate host defense显示文摘The antimicrobial properties of host derived lipids have become increasingly recognized and evidence is mounting that antimicrobial lipids(AMLs),like antimicrobial peptides,are effector molecules of the innate immune system and are regulated by its conserved pathways.This review,with primary focus on the human body,provides some background on the biochemistry of lipids,summarizes their biological functions,expands on their antimicrobial properties and site-specific composition,presents modes of synergism with antimicrobial peptides,and highlights the more recent reports on the regulation of AML production as well as bacterial resistance mechanisms.Based on extant data a concept of innate epithelial defense is proposed where epithelial cells,in response to microbial products and proinflammatory cytokines and through activation of conserved innate signaling pathways,increase their lipid uptake and up-regulate transcription of enzymes involved in lipid biosynthesis,and induce transcription of antimicrobial peptides as well as cytokines and chemokines.The subsequently secreted antimicrobial peptides and lipids then attack and eliminate the invader,assisted by or in synergism with other antimicrobial molecules delivered by other defense cells that have been recruited to the site of infection,in most of the cases.This review invites reconsideration ofthe interpretation of cholesteryl ester accumulation in macrophage lipid droplets in response to infection as a solely proinflammatory event,and proposes a direct antimicrobial role of lipid droplet-associated cholesteryl esters.Finally,for the interested,but new-to-the-field investigator some starting points for the characterization of AMLs are provided.Before it is possible to utilize AMLs for anti-infectious therapeutic and prophylactic approaches,we need to better understand pathogen responses to these lipids and their role in the pathogenesis of chronic infectious disease. | Edith Porter Daniel C Ma Sandy Alvarez Kym F Faull | 2015 | World Journal of Immunology2015，5，2： | 0 |
| 17 | Role of capsule endoscopy in inflammatory bowel disease:Anything new?显示文摘Capsule endoscopy(CE)is a recently developed diagnostic method for diseases of the small bowel that is non-invasive,safe,and highly tolerable.Its role in patients with inflammatory bowel disease has been widely validated in suspected and established Crohn’s disease(CD)due to its ability to assess superficial lesions not detected by cross-sectional imaging and proximal lesions of the small bowel not evaluable by ileocolonoscopy.Because CE is a highly sensitive but less specific technique,differential diagnoses that can simulate CD must be considered,and its interpretation should be supported by other clinical and laboratory indicators.The use of validated scoring systems to characterize and estimate lesion severity(Lewis score,Capsule Endoscopy Crohn’s Disease Activity Index),as well as the standardization of the language used to define the lesions(Delphi Consensus),have reduced the interobserver variability in CE reading observed in clinical practice,allowing for the optimization of diagnoses and clinical management strategies.The appearance of the panenteric CE,the incorporation of artificial intelligence,magnetically-guided capsules,and tissue biopsies are elements that contribute to CE being a promising,unique diagnostic tool in digestive tract diseases. | Edith Pérez de Arce Rodrigo Quera Paulina Núñez F Raúl Araya | 2021 | Artificial Intelligence in Gastrointestinal Endoscopy2021，2，4： | 0 |
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