|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019，4，4： | 2 |
| 2 | Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)显示文摘 | Eng L F Ghirnikar R S Lee Y L | 2000 | Neurochem Res2000，25，910： | 2 |
| 3 | Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke: The Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) Study显示文摘 | Peter J. Kelly Jason D. Morrow MingMing Ning Walter Koroshetz Eng H. Lo Erin Terry Ginger L. Milne Jane Hubbard Hang Lee Elizabeth Stevenson Megan Lederer Karen L Furie | 2008 | Stroke2008，，1： | 2 |
| 4 | Corporate governance and voluntary disclosure显示文摘 | Eng L L Mak Y T | 2003 | Journal of Accounting and Public Policy2003，22，4： | 1 |
| 5 | PTEN induces apoptosis and cell cycle arrest through phosphoinosistol - 3 - kinase/Akt - dependent and independent pathways 显示文摘 | Weng L Brown JL Eng C | 2001 | Hum Mol Gent2001，10，3： | 1 |
| 6 | Germline Epigenetic Regulation of KILLIN in Cowden and Cowden-like Syndrome 显示文摘 | Bennett K L Mester J Eng C | 2010 | J AMA-J Am Med Assoc2010，304，24： | 1 |
| 7 | Isolation and characterization of exendin-4, an exendin-analogue, from Heloderma suspectum venom: further evidence for an exendin receptor on dispersed acini from guinea pig pancreas 显示文摘 | ENG J KLEINMAN W A SINGH L | 1992 | J Biol Chem1992，267，11： | 1 |
| 8 | 3D-steering and superfo- cusing of second-harmonic radiation through plasmonie nano antenna arrays显示文摘 | Reichenbach P Eng L M Georgi U | 2012 | Journal of Laser Applications2012，24，04： | 1 |
| 9 | 显示文摘 | Setter N Damjanovic D Eng L | 2006 | J Appl Phys2006，100，5： | 1 |
| 10 | Noise adaptive soft-switching median filter显示文摘 | Eng H L Ma K K | 2001 | IEEE Transactions on Image Processing2001，10，2： | 1 |
| 11 | Pleomorphic xanthoastroeyto- ma:a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis, a study of 12 cases显示文摘 | Kepes J J Rubinstein L J Eng L F | 1979 | Cancer1979，44，5： | 1 |
| 12 | Investigation of the Environmental Kuznets Curve for carbon emissions in Malaysia: Do foreign direct investment and trade matter? 显示文摘 | LAU L CHOONG C ENG Y | 2014 | Energy Policy2014，68，： | 1 |
| 13 | Isolation and characterization of exendin-4,an exendin-3 analogue from Heloderma suspectum venom显示文摘 | Eng J Kleinman W A Singh L | 1992 | J Biol Chem1992，267，： | 1 |
| 14 | Oral fluoropyrimidine treatment of colorectal cancer显示文摘 | Eng C Kindler H L Schilsky R L | 2001 | Clin Colorectal Cancer2001，1，2： | 1 |
| 15 | Cervical Cancer Prevention: A- sian - American Women's Knowledge and Participation in Screening Practices显示文摘 | Robison K Clark L Eng W | 2014 | Womens Health Issues2014，24，2： | 1 |
| 16 | Usefulness of clinical prediction rules for the diagnosis of venous thromboembolism:a systematic review显示文摘 | Tamariz L J Eng J Segal J B | 2004 | The American Journal of Medicine2004，117，9： | 1 |
| 17 | PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways 显示文摘 | Weng L Brown J Eng C | 2001 | Hum Mol Genet2001，10，3： | 1 |
| 18 | Effect of stroke on fall rate, location and predictors: a prospective comparison of older adults with and without stroke 显示文摘 | SIMPSON L A MILLER W C ENG J J | 2011 | PLoS One2011，6，19： | 1 |
| 19 | Corporate Governance and Voluntary Disclosure 显示文摘 | Eng L L Mak Y T | 2003 | Journal of Accounting and Public Policy2003，22，4： | 1 |
| 20 | Comparison of diversity combining techniques for Rayleigh-fading channels 显示文摘 | Eng T Kong Ning Milstein L B | 1996 | IEEE Transactions on Communications1996，44，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员