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| 1 | Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers显示文摘Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide,due to late detection and high recurrence rates.Today,these cancers have a heavy socioeconomic burden,for which a full understanding of their pathophysiological features is warranted to search for promising biomarkers and therapeutic targets.Osteopontin (OPN) is overexpressed in most patients with gastric and liver cancers.Over the past decade,emerging evidence has revealed a correlation of OPN level and clinicopathological features and prognosis in gastric and liver cancers,indicating its potential as an independent prognostic indicator in such patients.Functional studies have verified the potential of OPN knockdown as a therapeutic approach in vitro and in vivo .Furthermore,OPN mediates multifaceted roles in the interaction between cancer cells and the tumor microenvironment,in which many details need further exploration.OPN signaling results in various functions,including prevention of apoptosis,modulation of angiogenesis,malfunction of tumor-associated macrophages,degradation of extracellular matrix,activation of phosphoinositide 3-kinase-Akt and nuclear factor-κB pathways,which lead to tumor formation and progression,particularly in gastric and liver cancers.This editorial aims to review recent findings on alteration in OPN expression and its clinicopathological associations with tumor progression,its potential as a therapeutic target,and putative mechanisms in gastric and liver cancers.Better understanding of the implications of OPN in tumorigenesis might facilitate development of therapeutic regimens to benefit patients with these deadly malignancies. | Dong-Xing Cao Zhi-Jie Li Xiao-Ou Jiang Yick Liang Lum Ester Khin Nikki P Lee Guo-Hao Wu John M Luk | 2012 | World Journal of Gastroenterology2012，18，30： | 29 |
| 2 | Wireless sensor network survey显示文摘 | Jennifer Yick Biswanath Mukherjee Dipak Ghosal | 2008 | Computer Networks2008，，12： | 5 |
| 3 | Purchasing Behaviour of University Students towards Cyber Shopping in Hong Kong显示文摘The developments of Internet and e-commerce provide a new market place to businessman to sell their products and allow people to buy products via Internet as well as to create a new shopping media to consumers. The study aims to investigate the factors affecting consumers' purchase decision via Internet and how product characteristics affect cyber shopping in Hong Kong. The study has revealed that the security of personal data,delivery time, product brand and price were the major concerns for developing cyber market. For marketing apparel products, brand loyalty becomes very important since consumers' judging confidence on the products can be increased in terms of fitting standards and quality aspects. | Cheng Miu-tsz(郑妙紫) Yick Kit-lun(易洁伦) | 2001 | Journal of Donghua University(English Edition)2001，18，1： | 2 |
| 4 | Wireless sensor network survey显示文摘 | Jennifer Yick Biswanath Mukherjee Dipak Ghosal | 2008 | Computer Networks2008，，12： | 2 |
| 5 | Chondroitinase ABC promotes axonal regeneration of Clark's neurons after spinal cord injury 显示文摘 | Yick LW Wu W So KF | 2000 | Neuroreport2000，11，5： | 1 |
| 6 | Wireless sensor network survey显示文摘 | YICK J MUKHERIEE B GHOSAL D | 2008 | Comp Netw2008，52，12： | 1 |
| 7 | Wireless sensor network survey 显示文摘 | YICK J MUKHERJEE B GI-IOSAL D | 2008 | Computer Networks2008，52，12： | 1 |
| 8 | Energy storage polymer/MicroPCMs blended chips and thermo-regulated fibers显示文摘 | X. X. Zhang X. C. Wang X. M. Tao K. L. Yick | 2005 | Journal of Materials Science2005，，14： | 1 |
| 9 | Wireless sensor network survey显示文摘 | Yick J Mukherjee B Ghosal D | 2008 | Computer Networks2008，52，： | 1 |
| 10 | Structure and thermal stability of microencapsulated phase-change materials显示文摘 | Xing-xiang Zhang Xiao-ming Tao Kit-lun Yick Xue-chen Wang | 2004 | Colloid and Polymer Science2004，，4： | 1 |
| 11 | Wireless sensor network survey显示文摘 | Jennifer Yick Biswanath Mukherjee Dipak Ghosal | | 0，，12： | 1 |
| 12 | NAFLD or MAFLD:the data behind the debate显示文摘Since its introduction in the 1980s(1),there has been substantial growth in the knowledge of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis(NAFLD/NASH).This is of utmost importance as the disease burden of NAFLD has grown globally as evidenced by its increase in disability-adjusted life-years when compared to other causes for liver disease regardless of region(2).However,despite great advances,there has been discontent with the nomenclature as it may not perfectly capture this heterogeneous disease entity.In response,an international panel proposed replacing NAFLD/NASH with metabolic(dysfunction)associated fatty liver disease(MAFLD)(3).In MAFLD,diagnosis would focus more on presence of risk factors contributing to metabolic dysfunction in the presence of fatty liver,as opposed to just the exclusion of high alcohol intake.It is noted that although most patients with hepatic steatosis who currently carry the diagnosis of NAFLD likely would also meet the criteria for MAFLD. | Frederick Yick Kaveh Hajifathalian | 2022 | Hepatobiliary Surgery and Nutrition2022，11，3： | 1 |
| 13 | Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury显示文摘 | So KF Cheung PT | 2004 | J Neurotrauma2004，21，7： | 1 |
| 14 | Wireless sensor network survey 显示文摘 | YICK J MUKHERJEE B GHOSAL D | 2008 | Computer Networks2008，52，12： | 1 |
| 15 | Wireless sensor networks survey显示文摘 | Yick J Mukherjee B Chosal D | 2008 | Computer Networks2008，52，12： | 1 |
| 16 | Scouring erosion resistance of metallic materials used in slurry pump service显示文摘 | Llewellyn R J Yick S K Dolmanb K F | 2004 | Wear2004，，256： | 1 |
| 17 | Wirelesssensor network sur- vey显示文摘 | Yick J Mukherjee B Ghosal D | 2008 | Computer Networks2008，52，12： | 1 |
| 18 | Wireless sensor network survey显示文摘 | YICK J MUKHERJEE B GHOSAL D | 2008 | Computer Networks2008，52，12： | 1 |
| 19 | Wireless sensor network survey 显示文摘 | Yick J Mukherjee B Ghosal D | 2008 | Computer NetWorks2008，52，12： | 1 |
| 20 | Wireless sensor network survey 显示文摘 | YICK J MUKHERJEE B GHOSAL D | 2008 | Computer Networks2008，52，12： | 1 |
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