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60篇 您的检索式：作者名="Dicker M"

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	题名	作者	年代	出处	被引量
1	RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone.	Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M	2013	中国神经肿瘤杂志2013，11，1：	8
2	Functional studies of mesenchymal stem cells derived from adult human adipose tissue显示文摘	Andrea Dicker Katarina Le Blanc Gaby ?str?m Vanessa van Harmelen Cecilia G?therstr?m Lennart Blomqvist Peter Arner Mikael Rydén	2005	Experimental Cell Research2005，，2：	2
3	Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes显示文摘	van Harmelen V Dicker A Ryden M	2002	Diabetes2002，51，7：	1
4	Relationship between varicocecle size and response to varicocelectomy 显示文摘	STECKEL J DICKER A P GOLDSTEIN M	1993	J Urol1993，149，4：	1
5	Microsugical Inguinal Varicocelectomy with Delivery of the Testis: an artery and lymphatic sparing technigue 显示文摘	Goldstein M Gibert BR Dicker AP	1992	J Urol1992，148，6：	1
6	Green compo- sites: A review of material attributes and complementary applications 显示文摘	Dicker M P Duckworth P F Baker A B	2014	Composites Part A: Appl Sci Manuf2014，56，：	1
7	Functional characterization of human mesenchymal stem cell-derived adipocytes显示文摘	Ryden M Dicker A Gotherstrom C	2003	Biochem Biophys Res Commun2003，311，2：	1
8	Microsurgical inguinal varicocelectomy with delivery of the testis:an artery and lymphatic sparing technique显示文摘	Goldstein M Gilbert B R Dicker A P	1992	J Urol1992，148，6：	1
9	lnhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis 显示文摘	Kater AP Dicker F Mangiola M	2005	Blood2005，106，5：	1
10	Static and dynamic loading of mandibular condyles and their positional changes after bilateral sagittal split advancement osteotomies 显示文摘	Dicker GJ Tuijt M Koolstra JH	2012	Int J Oral Maxillofac Surg2012，41，9：	1
11	Usefulness of CT colonography in patients with incomplete colonoscopy显示文摘	Macari M Berman P Dicker M	1999	Am J Roentgenol1999，173，3：	1
12	Microsurgical inguinal varicocelectomy with delivery of the testis : an artery and lymphatic sparing technique显示文摘	Goldstein M Gilbert BR Dicker AP	1992	J Urol1992，148，6：	1
13	Assessment of epidermal growth factor receptor (EGFR) expression in human meningioma 显示文摘	Wemicke AG Dicker AP Whiton M	2010	Radiation Oncology2010，5，：	1
14	Biologically conformal treatment: biomarkers and functional imaging in radiation oncology 显示文摘	Lawrence YR Werner-Wasik M Dicker AP	2008	Future Oncnl2008，4，5：	1
15	Microsurgical inguinal varicoeeleetomy with delivery of the testis an artery and lymphatic sparing technique显示文摘	Goldstein M Gilbert BR Dicker AP	1992	J Urol1992，148，6：	1
16	Mapping of early signaling events in tumor necrosis factor-alpha-mediated lipolysis in human fat cells显示文摘	RYDEN M DICKER A van HARMELEN V	2002	J Biol Chem2002，277，2：	1
17	Microsugical inguinal varicocelectomy with delivery of the testis: anartery and lymphatic sparing technique 显示文摘	Goldstein M Gibert BR Dicker AP	1992	J Urol1992，148，6：	1
18	Hans plieninger:die synthese des 4-und 6-brom-indols und 4-und 6-amino-indols sowie einige umsetzungen dieser verbindungen显示文摘	Suehiro T Suhr K Dicker M	1955	Chem Ber1955，88，：	1
19	Molecularly imprinted sensors layers for the detection of polycyclic aromatic hydrocarbons in water显示文摘	Dicker FL Tortschanoff M	1999	Anal Chem1999，71，20：	1
20	Computed tomography study of the effect of orlistat on visceral adipose tissue volume in obese subjects 显示文摘	Dicker D Herskovitz P Katz M	2010	Isr Med Assoc J2010，12，4：	1

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