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15篇 您的检索式：作者名="Dicker M P"

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		题名	作者	年代	出处	被引量
	1	RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone.	Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M	2013	中国神经肿瘤杂志2013，11，1：	8
	2	Relationship between varicocecle size and response to varicocelectomy 显示文摘	STECKEL J DICKER A P GOLDSTEIN M	1993	J Urol1993，149，4：	1
	3	Green compo- sites: A review of material attributes and complementary applications 显示文摘	Dicker M P Duckworth P F Baker A B	2014	Composites Part A: Appl Sci Manuf2014，56，：	1
	4	Microsurgical inguinal varicocelectomy with delivery of the testis:an artery and lymphatic sparing technique显示文摘	Goldstein M Gilbert B R Dicker A P	1992	J Urol1992，148，6：	1
	5	Usefulness of CT colonography in patients with incomplete colonoscopy显示文摘	Macari M Berman P Dicker M	1999	Am J Roentgenol1999，173，3：	1
	6	Computed tomography study of the effect of orlistat on visceral adipose tissue volume in obese subjects 显示文摘	Dicker D Herskovitz P Katz M	2010	Isr Med Assoc J2010，12，4：	1
	7	Microsurgical inguinal varicocelectomy with delivery of the testis:An artery and lymphatic sparing technique显示文摘	Goldstein M Gilbert B R Dicker A P	1992	JUrol1992，148，：	1
	8	Common proteomic changes in the hippocampus in schizophrenia and bipolar disorder and particular evidence for involvement of cornu ammonis regions 2 and 3 显示文摘	Focking M Dicker P English J A	2011	Arch Gen Psychiatry2011，68，5：	1
	9	Differentia- tion of vascular and non-vascular skin spectral signatures using in vivo hyperspectral radiometricinmging : implications for monitoring angiogenesis显示文摘	TUMEH P C LERNER J M DICKER D T	2007	Cancer Biol Ther2007，6，3：	1
	10	Abrin poisoning 显示文摘	Dickers K J Bradberry S M Rice P	2003	Toxicol Rev2003，22，3：	1
	11	Microsurgi- cal inguinal varicocelectomy with delivery of the testis: An artery and lymphatic sparing technique显示文摘	GOLDSTEIN M GILBERT B R DICKER A P	1992	J Uml1992，148，6：	1
	12	Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis显示文摘	Dicker F Mangiola M	2005	Blood2005，106，5：	1
	13	Relationship between varicocele size and response to varicoceletomy显示文摘	Steckel J Dicker A P Goldstein M	1993	J Urol1993，149，4：	1
	14	Charge mobilities in organic semiconducting materials de-termined by pulse-radiolysis time-resolved microwaveconductivity:π-bond-conjugated polymers versusπ-πstacked discotics显示文摘	John M Warman Matthijs P de Haas Gerald Dicker	2004	Chem Mater2004，16，23：	1
	15	Proteomic analysis of human hip- pocampus shows differential protein expression in the different hipp- ocampal subfields 显示文摘	Focking M Chen WQ Dicker P	2012	Proteomics2012，12，1516：	1

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