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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018，61，6： | 39 |
| 2 | Analysis of sensitivity and errors in Maglev vibration test system显示文摘In order to improve work performance of M aglev vibration test systems,the relationships of operating parameters between different components and system were researched. The working principle of photoelectric displacement sensor was analyzed. The relationship between displacement of transducer and the infrared light area received by sensor was given. The method of expanding the dynamic range of vibrator was proposed,which makes dynamic range of Maglev vibrator doubled. By increasing the amplification of the amplifier,the sensitive photoelectric displacement sensor can be maintained. Two modes of operation of the controller were analyzed. Bilateral work of vibration test system designed can further improve the stability of the system.An object vibration was measured by Maglev vibration test system designed when different vibration exciter frequencies were loaded. Experiments showthat the output frequency measured by Maglev vibration test system and loaded are the same. Finally,the errors of test system were analyzed. These errors of vibration test system designed can meet the requirements of application. The results laid the foundation for the practical application of magnetic levitation vibration test system. | JIANG Dong LIU Xukun WANG Deyu YANG Jiaxiang | 2016 | Instrumentation2016，3，1： | 24 |
| 3 | Completeness in the sense of Cauchy principal value of the eigenfunction systems of infinite dimensional Hamiltonian operator显示文摘The properties of eigenvalues and eigenfunctions of the infinite dimensional Hamiltonian operators are studied, and the suffcient conditions of the completeness in the sense of Cauchy principal value of the eigenfunction systems of the infinite dimensional Hamiltonian operators are given. In the end, concrete examples are constructed to justify the effectiveness of the criterion. | Alatancang WU DeYu | 2009 | Science China Mathematics2009，52，1： | 22 |
| 4 | Stable carbon and hydrogen isotopes of gases from the large tight gas fields in China显示文摘By the end of the year 2010,a total of 15 large tight gas fields have been found in China,located in the Ordos,Sichuan,and Tarim basins.The annual production and total reserves of these fields in 2010 were 222.5×108and 28657×108m3,respectively,accounting for 23.5%and 37.3%,respectively,of the total annual production and reserves of natural gases in China.They took a major part of all natural gas production and reserves in China.According to the analyses of 81 gas samples,the stable carbon and hydrogen isotopic compositions of tight gases in China have following characteristics:(1)Plots of 13C1-13C2-13C3,13C1-C1/C2+3and 13C1-13C2demonstrate the coal-derived origin of tight gases in China;(2)For the primary alkane gases,both carbon and hydrogen isotopic values increase with increasing molecular mass,i.e.,13C1<13C2<13C3<13C4and2H1<2H2<2H3;(3)The isotopic differences of 13C2-13C1,13C3-13C1,2H2-2H1and 2H3-2H1decrease with increasing Ro(%)and C1/C1–4;(4)There are seven causes for the carbon and hydrogen isotopic reversal,however,the carbon and hydrogen isotopic reversal of tight gases in China is caused mainly by multiple stages of gas charge and accumulation. | DAI JinXing NI YunYan HU GuoYi HUANG ShiPeng LIAO FengRong YU Cong GONG DeYu WU Wei | 2014 | Science China Earth Sciences2014，57，1： | 17 |
| 5 | Evolution and variation of the Tsushima warm current during the late Quaternary: Evidence from planktonic foraminifera, oxygen and carbon isotopes显示文摘The evolution and variation history of the Tsushima warm current during the late Quaternary was reconstructed based on the quantitative census data of planktonic foraminiferal fauna, together with oxygen and carbon isotope records of mixed layer dweller G. ruber and thermocline dweller N. dutertrei in piston core CSH1 and core DGKS9603 collected separately from the Tsushima warm current and the Kuroshio dominated area. The result showed that the Tsushima warm current vanished in the lowstand period during 40―24 cal ka BP, while the Kuroshio still flowed across the Okinawa Trough, arousing strong upwelling in the northern Trough. Meanwhile, the influence of freshwater greatly increased in the northern Okinawa Trough, as the broad East China Sea continental shelf emerged. The freshwater reached its maximum during the last glacial maximum (LGM), when the upwelling obviously weakened for the lowest sea-level and the depression of the Kuroshio. The modern Tsushima warm current began its development since 16 cal ka BP, and the impact of the Kuroshio increased in the middle and north- ern Okinawa Trough synchronously during the deglaciation and gradually evolved as the main water source of the Tsushima current. The modern Tsushima current finally formed at about 8.5 cal ka BP, since then the circulation structure has been relatively stable. The water of the modern Tsushima cur- rent primarily came from the Kuroshio axis. A short-term wiggle of the current occurred at about 3 cal ka BP, probably for the influences from the enhancement of the winter monsoon and the depression of the Kuroshio. The cold water masses greatly strengthened during the wiggle. | LI TieGang SUN RongTao ZHANG DeYu LIU ZhenXia LI Qing JIANG Bo | 2007 | Science China Earth Sciences2007，50，5： | 15 |
| 6 | Research on magnetic levitation absolute vibration measurement method in vehicles显示文摘This paper presents a design for a magnetic levitation absolute- vibration test system which can be used by vehicles to measure the road surface roughness. The relationship between the vibration test system output voltage and measured speed of the object was obtained through testing,the power spectrum of the measured signal was obtained by virtual instrument analysis,the vibration waveforms of the vehicle over gentle and steep slopes were measured respectively and the road surface roughness was obtained by waveform analysis. Data was saved where the waveforms exceeded threshold. Finally,the steep slope was located using a GPS system. Experimental results show that the magnetic levitation absolute- vibration measurement method has characteristics of high sensitivity and a wide frequency range. This lays the foundation for research into multi- dimensional vibration measurements through magnetic levitation vibration test systems in vehicles. | JIANG Dong SHAN Yi WANG Deyu YANG Jiaxiang | 2014 | Instrumentation2014，1，2： | 15 |
| 7 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 8 | The ClassⅢHistone Deacetylase Sirtuin 1 in Immune Suppression and Its Therapeutic Potential in Rheumatoid Arthritis显示文摘Rheumatoid arthritis(RA) is a chronic debilitating disease of the joints.Both the innate and adaptive immune responses participate in the development and progression of RA.While several therapeutic reagents,such as TNF-αagonists,have been successfully developed for the clinical use in the treatment of RA,more than half of the patients do not respond to anti-TNF therapy.Therefore,new therapeutic reagents are needed.Recent studies have shown that sirtuin 1(Sirtl),a nicotinamide adenine dinucleotide(NAD)-dependent histone deacetylase,is a critical negative regulator of both the innate and adaptive immune response in mice,and its altered functions are likely to be involved in autoimmune diseases.Small molecules that modulate Sirtl functions are potential therapeutic reagents for autoimmune inflammatory diseases.This review highlights the role of Sirtl in immune regulation and RA. | Sinyi Kong Pricilla Yeung Deyu Fang | 2013 | Journal of Genetics and Genomics2013，40，7： | 12 |
| 9 | Numerical Simulation and Analysis of Power Consumption and Metzner-Otto Constant for Impeller of 6PBT显示文摘Majority of non-Newtonian fluids are pseudoplastic with shear-thinning property,which means that the viscosity will be different in different parts of the stirred tank.In such mixing process,it is difficult to predict accurately the power consumption and mean shear rate for designing novel impeller.Metzner-Otto method is a widely accepted method to solve these questions in mixing non-Newtonian fluids.As a result,Metzner-Otto constant will become a key factor to achieve an optimum way of economical mixing.In this paper,taking glycerine and xanthan gum solutions as research system,the power consumption,stirred by the impeller composed of perturbed six-bent-bladed turbine(6PBT)with differently geometrical characteristics in a cylindrical vessel,is studied by means of computational fluid dynamics(CFD).The flow is modeled as laminar and a multiple reference frame(MRF)approach is used to solve the discretized equations of motion.In order to determine the capability of CFD to forecast the flow process,the torque test experiment is used to measure the glycerine solution power consumption.The rheological properties of the xanthan gum solutions are determined by a Brookfield rheometer.It is observed that the power consumption predicted by numerical simulation agrees well with those measured using torque experiment method in stirring glycerine solution,which validate the numerical model.Metzner-Otto constant is almost not correlated with the flow behavior index of pseudoplastic fluids.This paper establishes the complete correlations of power constant and Metzner-Otto constant with impeller geometrical characteristics through linear regression analysis,which provides the valuable instructions and references for accurately predicting the power consumption and mean shear rate of pseudoplastic fluids in laminar flow,comparatively. | LUAN Deyu CHEN Qiao ZHOU Shenjie | 2014 | Chinese Journal of Mechanical Engineering2014，27，3： | 11 |
| 10 | Identification of genomic regions determining flower and pod numbers development in soybean (Glycine max L.)显示文摘Flower and pod numbers per plant are important agronomic traits underlying soybean yield. So far quantitative trait loci (QTL) detected for flower and pod-related traits have mainly focused on the final stage, and might therefore have ignored genetic effects expressed during a specific developmental stage. Here, dynamic expressions of QTL for flower and pod numbers were identified using 152 recom-binant inbred lines (RILs) and a linkage map of 306 markers. Wide genetic variation was found among RILs; 17 unconditional and 18 conditional QTL were detected for the two traits at different developmental stages over two years. Some QTL were detected only at one stage and others across two or more stages, indicating that soybean flower and pod numbers development may be governed by time-dependent gene expression. Three main QTL (qfn-Chr18-2, qfn-Chr20-1, and qfn-Chr19) were detected for flower number, and two main QTL (qpn-Chr11 and qpn-Chr20) were detected for pod number. The phenotypic variation explained by them ranged from 6.1% to 34.7%. The markers linked to these QTL could be used in marker-assisted selection for increasing soybean flower and pod numbers, with the ultimate aim of increasing soybean yield. Comparison of the QTL regions for flower and pod numbers traits with the related genes reported previously showed that seven and four related genes were located in the QTL regions of qfn-Chr11 and qfn-Chr19, respectively. These results provide a basis for fine mapping and cloning of flower and pod development-related genes. | Dan Zhang, Hao Cheng, Hui Wang, Hengyou Zhang, Chunying Liu, Deyue Yu National Center for Soybean Improvement, National Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, China | 2010 | Journal of Genetics and Genomics2010，37，8： | 11 |
| 11 | Optimal Structural Design of the Midship of a VLCC Based on the Strategy Integrating SVM and GA显示文摘在这份报纸,当模特儿和优化的一个混合过程,集成一台支持向量机器(SVM ) 和基因算法(GA ) ,被介绍在轮船的结构的优化减少高时间费用。SVM,根植于统计学习理论和结构的风险最小化的方法的近似实现,能在真实问题并且因而的输入产量关系高减少的 metamodeling 提供好归纳表演时间在真实问题的分析花费了,例如女性的分析。作为一种强大的优化技术, GA 为几乎不能与普通基于坡度的优化方法被优化的问题拥有显著优点,它为优化 SVM 造的模型使它合适。基于 SVM-GA 策略,在一个很大的粗略的搬运人( VLCC )的船体中央部的结构的少量的优化轮船在普通结构的规则( CSR )根据直接力量评价方法被执行,它最后在优化轮船表明 SVM-GA 的高效率在重计算复杂性下面的结构的少量。有 SVM-GA 的这优化的时间费用严厉地被减少了,许多更多的环在时间的小数量以内被处理了,设计显著地被改进了。 | Li Sun (1) welqi1986@gmail.com Deyu Wang (1) | 2012 | Journal of Marine Science and Application2012，11，1： | 11 |
| 12 | Detection and fine-mapping of SC7 resistance genes via linkage and association analysis in soybean显示文摘Soybean mosaic virus(SMV) disease is one of the most serious and broadly distributed soybean(Glycine max(L.) Merr.) diseases. Here, we combine the advantages of association and linkage analysis to identify and fine-map the soybean genes associated with resistance to SMV strain SC7.A set of 191 soybean accessions from different geographic origins and 184 recombinant inbred lines(RILs) derived from Kefeng No.1(resistant) Nannong 1138-2(susceptible) were used in this study. The SC7 resistance genes were previously mapped to a 2.65 Mb region on chromosome 2 and a 380 kb region on chromosome 13. Among 19 single nucleotide polymorphisms(SNPs) detected via association analysis in the study, the SNP BARC-021625-04157 was located in the2.65 Mb region, and the SNP BARC-041671-08065 was located near the 380 kb region; three genes harboring the SNPs were probably related to SC7 resistance. The resistance gene associated with BARC-021625-04157 was then finemapped to a region of approximately 158 kb on chromosome2 using 184 RILs. Among the 15 genes within this region, one NBS-LRR type gene, one HSP40 gene and one serine carboxypeptidase-type gene might be candidate SC7 resistance genes. These results will be useful for map-based cloning and marker-assisted selection in soybean breeding programs. | Honglang Yan Hui Wang Hao Cheng Zhenbin Hu Shanshan Chu Guozheng Zhang Deyue Yu | 2015 | Journal of Integrative Plant Biology2015，57，8： | 10 |
| 13 | Kinetic analysis of self-condensing vinyl polymerization with unequal reactivities显示文摘The distribution function of the hyperbranched polymers formed from the self-condensing vinyl polymerization with unequal reactivities was derived and the differential equations for the second moments are established, based on the variable of the conversion of B* groups. The various average degrees of branching can be designed by suitable values of reactivities ratio (r) and the conversion of A group (x). In order to reach the maximum degree of branching at a specified x, r needed is dependant on the value of x. The higher the x, the less the r needed is for the maximum value of degree of branching. At the end of the reaction, the maximum degree of branching reaches 0.5 with r=2.59. | ZHOU ZhiPing WANG GaiJuan YAN DeYue | 2008 | Chinese Science Bulletin2008，53，22： | 9 |
| 14 | Features of the fault system and its relationship with migration and accumulation of hydrocarbon in Liaodong Bay显示文摘The fault system of Liaodong Bay developed extensively under the control of the Tanlu Fault.The fault system can be grouped into strike-slip faults of grade I,trunk faults of grade II and branch faults (induced faults) of grade III respectively based on its developmental scale.The faults of grade I and II were deep,early and large while the faults of grade III were shallow,late and small.The formation,evolution and distribution features played a significant role in controlling the migration of oil and gas in both horizontal and vertical directions.The fluid transfer in the fault system occurred in the process of faulting.The strike-slip and trunk faults moved actively forming predominant pathways for oil and gas migration.The branch faults,with weak activity,generally controlled the development of traps and were beneficial for the accumulation and preservation of oil and gas.The faults of grade I and II formed the major migration pathways for oil and gas,but their fault activity rates appeared to vary along their strikes.The zones with a relatively low fault activity rate might be favorable for oil and gas accumulation.When the activities of strike-slip,trunk,and branch faults came to a halt,the fault seal behavior had a vitally important effect on the accumulation of oil and gas.The controlling role of the fault over fluid distribution was further analyzed by calculating the fault activity quantitatively. | Xu Guosheng Ma Ruolong Gong Deyu Zhou Donghong Li Jianping Guo Yonghua Yuan Haifeng Wu Changrong | 2011 | Petroleum Science2011，8，3： | 8 |
| 15 | Mapping QTLs for seed yield and drought susceptibility index in soybean (Glycine max L.) across different environments显示文摘Drought stress has long been a major constraint in maintaining yield stability of soybean(Glycine max(L.) Merr.) in rainfed ecosystems.The identification of consistent quantitative trait loci(QTL) involving seed yield per plant(YP) and drought susceptibility index(DSI) in a population across different environments would therefore be important in molecular marker-assisted breeding of soybean cultivars suitable for rainfed regions.The YP of a recombinant line population of 184 F2:7:11 lines from a cross of Kefeng1 and Nan-nong1138-2 was studied under water-stressed(WS) and well-watered(WW) conditions in field(F) and greenhouse(G) trials,and DSI for yield was calculated in two trials.Nineteen QTLs associated with YP-WS and YP-WW,and 10 QTLs associated with DSI,were identified.Comparison of these QTL locations with previous findings showed that the majority of these regions control one or more traits related to yield and other agronomic traits.One QTL on molecular linkage group(MLG) K for YP-F,and two QTLs on MLG C2 for YP-G,remained constant across different water regimes.The regions on MLG C2 for YP-WW-F and MLG H for YP-WS-F had a pleiotropic effect on DSI-F,and MLG A1 for YP-WS-G had a pleiotropic effect on DSIG.The identification of consistent QTLs for YP and DSI across different environments will significantly improve the efficiency of selecting for drought tolerance in soybean. | Weijun Du Min Wang Sanxiong Fu Deyue Yu | 2009 | Journal of Genetics and Genomics2009，36，12： | 8 |
| 16 | Drug release property of a pH-responsive double-hydrophilic hyperbranched graft copolymer显示文摘In this paper, we report the synthesis and self-assembly of double-hydrophilic hyperbranched graft copolymers of HPG-g-PDMAEMA, which consist of a hyperbranched polyglycerol (HPG) core and several grafted poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) arms. HPG was synthesized by cationic polymerization. Then HPG-Br macroinitiator was obtained by esterification of HPG with 2-bromoisobutyryl bromide, which was subsequently used in the preparation of HPG-g-PDMAEMA graft copolymers through atom transfer radical polymerization (ATRP) of DMAEMA monomers. The molecular structures were studied by 1H NMR and GPC. The pyrene-based fluorescent probe method, 1H NMR and DLS were used to study the self-assembly behavior of HPG-g-PDMAEMA. The drug loading and pH-responsive release properties of HPG-g-PDMAEMA were also investigated by using coumarin 102 as a model drug. The results show that the HPG-g-PDMAEMA micelles can continuously release and re-encapsulate coumarin 102 as the pH continuously changes from 11.5 to 2.5; however, this process is not totally reversible. | SUN XiaoYi ZHOU YongFeng YAN DeYue | 2009 | Science China Chemistry2009，52，10： | 7 |
| 17 | Detection of Quantitative Trait Loci for Yield and Drought Tolerance Traits in Soybean Using a Recombinant Inbred Line Population显示文摘To investigate the genetic basis of drought tolerance in soybean(Glycine max L.Merr.) a recombinant inbred population with 184 F2:7:11 lines developed from a cross between Kefeng1(drought tolerant) and Nannong1138-2(drought sensitive) were tested under water-stressed and well-watered conditions in field and greenhouse trials.Traits measured included leaf wilting coefficient,excised leaf water loss and relative water content as indicators of plant water status and seed yield.A total of 40 quantitative trait loci(QTLs) were identified:17 for leaf water status traits under drought stress and 23 for seed yield under well-watered and drought-stressed conditions in both field and greenhouse trials.Two seed yield QTLs were detected under both well-watered and drought-stressed conditions in the field on molecular linkage group H and D1b,while two seed yield QTLs on molecular linkage group C2 were found under greenhouse conditions.Several QTLs for traits associated with plant water status were identified in both field and greenhouse trials,including two leaf wilting coefficient QTLs on molecular linkage group A2 and one excised leaf water loss QTL on molecular linkage group H.Phenotypic correlations of traits suggested several QTLs had pleiotropic or location-linked associations.These results will help to elucidate the genetic basis of drought tolerance in soybean,and could be incorporated into a marker-assisted selection breeding program to develop high-yielding soybean cultivars with improved tolerance to drought stress. | Weijun Du Deyue Yu Sanxiong Fu | 2009 | Journal of Integrative Plant Biology2009，51，9： | 7 |
| 18 | Formation and evolution of Sinian oil and gas pools in typical structures, Sichuan Basin, China显示文摘The only major breakthrough in the exploration of the Sinian of the Sichuan Basin has been the Weiyuan gas field. Taking the typical structures in the Sichuan Basin as examples, an apatite fission track simulation was applied to constrain the thermal evolutionary history of the source rocks in this study. Combined with trap formation and evolution, the formation, destruction, and accumulation history of the Sinian reservoirs were analyzed from a dynamic perspective. The Sinian reservoirs underwent several primary stages: the paleo-reservoir formation and destruction in the late Silurian, hydrocarbon recharge in the Permian-Triassic, the cracking of oil to gas and dissolved-gas in the late Triassic-Mid-Late Jurassic, and the exsolution and accumulation of dissolved-gas as a result of episodic uplift since the Late Cretaceous. The exsolution process of dissolved-gas is of great significance to the accumulation of natural gas. The formation of the Weiyuan gas field is also related to this process. The Sinian in the Sichuan Basin has a broad exploration prospect, and exploration targets focused on the Leshan-Longnüsi Paleo-uplift tectonic zone with weak influences on potential hydrocarbon reservoirs from the late tectonism and transformation. | Yuan Haifeng Liang Jiaju Gong Deyu Xu Guosheng Liu Shugen Wang Guozhi | 2012 | Petroleum Science2012，9，2： | 7 |
| 19 | Oral health in China: from vision to action显示文摘Chinese president Xi Jinping made clear at the National Health and Wellness Conference that health is the prerequisite for people's all-around development and a precondition for the sustainable development of China. Oral health is an indispensable component of overall health in humans. However, the long neglect of oral health in overall health agendas has made oral diseases an increasing concern. With this perspective, we described the global challenges of oral diseases, with an emphasis on the challenges faced by China. We also described and analyzed the recently released health policies of the Chinese government, which aim to guide midterm and long-term oral health promotion in China. More importantly, we called for specific actions to fulfill the larger goal of oral health for the nation. The implementation of primordial prevention efforts against oral diseases, the integration of oral health into the promotion of overall health, and the management of oral diseases in conjunction with other chronic non-communicable diseases with shared risk factors were highly recommended. In addition, we suggested the reform of standard clinical residency training, the development of domestic manufacturing of dental equipment and materials, the revitalization traditional Chinese medicine for the prevention and treatment of oral diseases, and integration of oral health promotion into the Belt and Road Initiative. We look forward to seeing a joint effort from all aspects of the society to fulfill the goal of Healthy China 2030 and ensure the oral health of the nation. | Xuedong Zhou Xin Xu Jiyao Li Deyu Hu Tao Hu Wei Yin Yujiang Fan Xingdong Zhang | 2018 | International Journal of Oral Science2018，10，1： | 7 |
| 20 | A New Rational-based Optimal Design Strategy of Ship Structure Based on Multi-level Analysis and Super-element Modeling Method显示文摘A new multi-level analysis method of introducing the super-element modeling method, derived from the multi-level analysis method first proposed by O. F. Hughes, has been proposed in this paper to solve the problem of high time cost in adopting a rational-based optimal design method for ship structural design. Furthermore,the method was verified by its effective application in optimization of the mid-ship section of a container ship. A full 3-D FEM model of a ship,suffering static and quasi-static loads, was used as the analyzing object for evaluating the structural performance of the mid-ship module, including static strength and buckling performance. Research results reveal that this new method could substantially reduce the computational cost of the rational-based optimization problem without decreasing its accuracy, which increases the feasibility and economic efficiency of using a rational-based optimal design method in ship structural design. | Li Sun Deyu Wang | 2011 | Journal of Marine Science and Application2011，10，3： | 6 |
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