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| 1 | Phase II trial of two-weekly gemcitabine in patients with advanced biliary?tract cancer显示文摘 | M. Penz G. V. Kornek M. Raderer H. Ulrich-Pur W. Fiebiger A. Lenauer D. Depisch G. Krauss B. Schneeweiss W. Scheithauer | 2001 | Annals of Oncology2001,,2: | 2 |
| 2 | Comparative analysis of CA72-4, CA195 and carcinoembryonic antigen in patients with gastrointestinal malignancies显示文摘 | G. V. Kornek D. Depisch H. R. Rosen E. M. Temsch W. Scheithauer | 1992 | Journal of Cancer Research and Clinical Oncology1992,,4: | 1 |
| 3 | Phase II trial of two-weekly gemcitabine in patients with advanced biliary?tract cancer显示文摘 | M. Penz G. V. Kornek M. Raderer H. Ulrich-Pur W. Fiebiger A. Lenauer D. Depisch G. Krauss B. Schneeweiss W. Scheithauer | 2001 | Annals of Oncology2001,,2: | 1 |
| 4 | MDR1 gene expression and its clinical relevance in primary gastric carcinomas显示文摘 | Wallner J Depisch D Gsur A | 1993 | Cancer1993,71,3: | 1 |
| 5 | Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer显示文摘 | Gerwin Heller Joseph Geradts Barbara Ziegler Irene Newsham Martin Filipits Eva-Maria Markis-Ritzinger Daniela Kandioler Walter Berger Wolfgang Stiglbauer Dieter Depisch Robert Pirker Christoph C. Zielinski Sabine Z?chbauer-Müller | 2007 | Breast Cancer Research and Treatment2007,,: | 1 |
| 6 | Adjuvant introperitoneal cisplatin chemotherapy does not improve long - term survival after surgery for advanced gastric cancer显示文摘 | Sautner T Hofbauer F Depisch P | 1994 | J Clin Oncol1994,12,: | 1 |
| 7 | Adjuvant intraperitoneal cisplatin chemothera- py does not improve long - term survival after surgery for advanced gastric cancer 显示文摘 | Sautner T Hofbauer F Depisch D | 1994 | J Clin Oncol1994,12,5: | 1 |
| 8 | MDR1 gene expression and its clinical relevance in primary gastric carcinomas显示文摘 | Wallner J Depisch D Gsur A | 1993 | Cancer1993,71,3: | 1 |
| 9 | Adjuvant intraperitoneal cisplatin chemotherapy does not improve long-term survival after surgery for advanced gastric cancer显示文摘 | Sautner T Hofbauer F Depisch D | 1994 | J Clin Onenl1994,12,5: | 1 |
| 10 | Phase II trial of two-weekly gemcitabine in patients with advanced biliary?tract cancer显示文摘 | M. Penz G. V. Kornek M. Raderer H. Ulrich-Pur W. Fiebiger A. Lenauer D. Depisch G. Krauss B. Schneeweiss W. Scheithauer | 2001 | Annals of Oncology2001,,2: | 1 |
| 11 | Randomized com parisonof fluorouracil and leucovorin therapy versus fluorouracil, leucovorin,and cisplatin therapy in patients with advanced colorectal cancer显示文摘 | Scheithauer W Depisch D Komek G | 1994 | Cancer1994,73,6: | 1 |
| 12 | MDR- 1 gene expression and its clinical relevance in primary gastric carcinomas显示文摘 | Wallner J Depisch D Gsur A | 1993 | Cancer1993,71,: | 1 |
| 13 | Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer显示文摘 | Gerwin Heller Joseph Geradts Barbara Ziegler Irene Newsham Martin Filipits Eva-Maria Markis-Ritzinger Daniela Kandioler Walter Berger Wolfgang Stiglbauer Dieter Depisch Robert Pirker Christoph C. Zielinski Sabine Z?chbauer-Müller | 2007 | Breast Cancer Research and Treatment2007,,3: | 1 |
| 14 | Adjuvant intraperi- tonealcisplatin chemotherapy does not improve long-term survival after sur-gery for advanced gastric cancer 显示文摘 | SautnerT HofbauerF Depisch D | 2004 | J Clin Oncol2004,12,5: | 1 |
| 15 | Mdr1 gene expression and its clinical relevancein primary gastric carcinomas显示文摘 | Wallner J Depisch D Gsur A | 1993 | Cancer1993,71,: | 1 |
| 16 | Adjuvant intraperitoneal cisplatin chemotherapy does not improve long-term survivalafter surgery for advanced gastric cancer显示文摘 | SAUTNER T HOFBAUER F DEPISCH D | 1994 | J Clin Oncol1994,12,: | 1 |
| 17 | M drl gene expression and its clinical relevancein primary gastric carcimmas显示文摘 | Wallnet J Depisch D Gsur A | 1993 | Cancer1993,71,: | 1 |
| 18 | Randomized comparison of fluorouracil and leucovorin versus fluorouracil leucovorin and cisplatin therapy in patients with Advanced colorectal cancer显示文摘 | Scheithauer W Depisch D Korner G | 1994 | Cancer1994,73,: | 1 |
| 19 | Experimental nerve transfer model in the neonatal rat显示文摘Clinically,peripheral nerve reconstructions in neonates are most frequently applied in brachial plexus birth injuries.Most surgical concepts,however,have investigated nerve reconstructions in adult animal models.The immature neuromuscular system reacts differently to the effects of nerve lesion and surgery and is poorly investigated due to the lack of reliable experimental models.Here,we describe an experimental forelimb model in the neonatal rat,to study these effects on both the peripheral and central nervous systems.Within 24 hours after birth,three groups were prepared:In the nerve transfer group,a lesion of the musculocutaneous nerve was reconstructed by selectively transferring the ulnar nerve.In the negative control group,the musculocutaneous nerve was divided and not reconstructed and in the positive control group,a sham surgery was performed.The animal's ability to adapt to nerve lesions and progressive improvement over time were depict by the Bertelli test,which observes the development of grooming.Twelve weeks postoperatively,animals were fully matured and the nerve transfer successfully reinnervated their target muscles,which was indicated by muscle force,muscle weight,and cross sectional area evaluation.On the contrary,no spontaneous regeneration was found in the negative control group.In the positive control group,reference values were established.Retrograde labeling indicated that the motoneuron pool of the ulnar nerve was reduced following nerve transfer.Due to this post-axotomy motoneuron death,a diminished amount of motoneurons reinnervated the biceps muscle in the nerve transfer group,when compared to the native motoneuron pool of the musculocutaneous nerve.These findings indicate that the immature neuromuscular system behaves profoundly different than similar lesions in adult rats and explains reduced muscle force.Ultimately,pathophysiologic adaptations are inevitable.The maturing neuromuscular system,however,utilizes neonatal capacity of regeneration and seizes a variety of compensation mechanism to restore a functional extremity.The above described neonatal rat model demonstrates a constant anatomy,suitable for nerve transfers and allows all standard neuromuscular analyses.Hence,detailed investigations on the pathophysiological changes and subsequent effects of trauma on the various levels within the neuromuscular system as well as neural reorganization of the neonatal rat may be elucidated.This study was approved by the Ethics Committee of the Medical University of Vienna and the Austrian Ministry for Research and Science(BMWF-66.009/0187-WF/V/3 b/2015)on March 20,2015. | Matthias E.Sporer Martin Aman Konstantin D.Bergmeister Dieter Depisch Katharina M.Scheuba Ewald Unger Bruno K.Podesser Oskar C.Aszmann | 2022 | Neural Regeneration Research2022,17,5: | 0 |