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| 1 | Correlation between expectations of recovery and injury severity perception in whiplash-associated disorders显示文摘Objective:To assess the correlation between expectations of recovery and whiplash patients' perceptions of injury severity using a simplified instrument.Expectations of recovery have been shown to predict rate of recovery from whiplash injury in population-based studies.The perception of having more severe pathology or more ominous diagnostic labels has also been associated with a worse prognosis.Methods:Consecutive patients with whiplash-associated disorder grade 1 or 2,presenting in the acute stage to a primary care centre,were asked 'do you think that your injury will…' with response options 'get better soon;get better slowly;never get better;don't know.' Injury severity perception (ISP) was measured with a numerical rating scale which ranged from 0-10,on which subjects were asked to rate how severe (in terms of damage) they thought their injury was.The anchors were labeled 'no damage' (0) and 'severe,and maybe permanent damage' (10).The primary outcome measure was the correlation between the subject's ISP score and expectation of recovery.Results:A total of 94 subjects (34 males,60 females,and mean age (40.6±10.0) years,range 19-60 years) were included.The initial responses to expectation of recovery were:get better soon (29/94);get better slowly (22/94);never get better (11/94);don't know (32/94).The mean ISP score was 4.9±1.7 (range 2-9 out of 10).There was a high correlation between expectations and ISP scores (Spearman's rank correlation coefficient 0.68).Those who expected to recover soon and those who expected to get better slowly had the lowest ISP scores.Conclusions:The more slowly whiplash patients expect to recover,or the less sure they are of recovery,the more severe their initial perceptions of injury. | Robert FERRARI Deon LOUW | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，8： | 2 |
| 2 | NOTUM inhibition increases endocortical bone formation and bone strength显示文摘The disability,mortality and costs caused by non-vertebral osteoporotic fractures are enormous.Existing osteoporosis therapies are highly effective at reducing vertebral but not non-vertebral fractures.Cortical bone is a major determinant of non-vertebral bone strength.To identify novel osteoporosis drug targets,we phenotyped cortical bone of 3 366 viable mouse strains with global knockouts of druggable genes.Cortical bone thickness was substantially elevated in Notum?/?mice.NOTUM is a secreted WNT lipase and we observed high NOTUM expression in cortical bone and osteoblasts but not osteoclasts.Three orally active small molecules and a neutralizing antibody inhibiting NOTUM lipase activity were developed.They increased cortical bone thickness and strength at multiple skeletal sites in both gonadal intact and ovariectomized rodents by stimulating endocortical bone formation.Thus,inhibition of NOTUM activity is a potential novel anabolic therapy for strengthening cortical bone and preventing non-vertebral fractures. | Robert Brommage Jeff Liu Peter Voge Faika Mseeh Andrea Y.Thompson David G.Potter Melanie K.Shadoan Gwenn M.Hansen Sabrina Jeter-Jones Jie Cui Dawn Bright Jennifer P.Bardenhagen Deon D.Doree Sofia Moverare-Skrtic Karin H.Nilsson Petra Henning Ulf H.Lerner Claes Ohlsson Arthur T.Sands James E.Tarver David R.Powell Brian Zambrowicz Qingyun Liu | 2019 | Bone Research2019，7，1： | 2 |
| 3 | Oxidative stress in plasma from maple syrup urine disease patients during treatment 显示文摘 | Barschak AG Sirra A Deon M et ul | 2008 | Metab Brain Dis2008，23，1： | 1 |
| 4 | A Review on Mosquitocidal Activity of Botanical Seed Derivatives显示文摘 | Essam A. Shaalan Deon V. Canyon | 2015 | Current Bioactive Compounds2015，，2： | 1 |
| 5 | Who Blinks in Volatile Markets, Individuals or Institutions 显示文摘 | Patrick J Dennis Deon Strickland | 2002 | The Journal of Finance October2002，57，5： | 1 |
| 6 | Factors influencing family business succession显示文摘 | Michael H Morris Roy W Williams Deon Nel | 1996 | International Journal Entrepreneurial Behavior & Research1996，2，3： | 1 |
| 7 | L-carnitine blood levels and oxidative stress in treated phenylketonuric patients显示文摘 | Sitta A Barschak AG Deon M | 2009 | Cell Mol Neurobio12009，29，2： | 1 |
| 8 | Snow depth as a function of canopy cover and other site attributes in a forested ungulate winter range in southeast British Columbia显示文摘 | DEon R | 2004 | BC Journal of Ecosys- tems and Management2004，3，2： | 1 |
| 9 | Do non-US firms issue equity on US stock exchanges to relax capital constraints显示文摘 | Lins Karl V Stfiekland Deon and Zenner Mare | | Journal of Financial and Quantitative Analysis 200 50，40，1： | 1 |
| 10 | Contribution of proteomics to the molecular analysis of renal cell carcinoma with an emphasis onmanganese superoxide dismutase 显示文摘 | Sarto C Deon C Doro G | 2001 | Proteomics2001，1，： | 1 |
| 11 | Characterization of a Novel Human Cell-Cycle-Regulated Homologue of Drosophila dlg1显示文摘 | Sahar Bassal Nobuo Nomura Deon Venter Karl Brand Michael J. McKay Peter J. van der Spek | 2001 | Genomics2001，，1： | 1 |
| 12 | L-carnitine blood levels and oxidative stress in treated phenylketonuric patients显示文摘 | Sitta A Barschak A G Deon M | 2009 | Cell Mol Neurobiol2009，29，2： | 1 |
| 13 | The vitamin D questions:How much do you need and how should you get it?显示文摘 | Wolpowitz Deon Gilchrest Barbara A | 2006 | Journal of the American Academy of Dermatology2006，54，2： | 1 |
| 14 | Rapid three-dimensional quantification of VEGF-induced scaffold neovascularisation by microcomputed tomography显示文摘 | Christian S Deon B Michael B | | 0，，： | 1 |
| 15 | L-carnitlne blood levels and oxidative stress in treated phenylketonuric patients 显示文摘 | Sitta A Barschak AG Deon M de Mari JF Barden AT Vanzin CS | 2009 | Cell Mol Neurobiol2009，29，2： | 1 |
| 16 | Do non-us firms issue stock on us equity markets to relax capital constraints显示文摘 | Lins Karl Deon Strickland Marc Zenner | 2005 | Journal of Financial and Quantitative Analysis2005，40，： | 1 |
| 17 | Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts显示文摘 | Deon D Ahmed S Tai K | 2001 | J Immunol2001，167，9： | 1 |
| 18 | Speaker model clustering for efficient speaker identification in large population appli- cations显示文摘 | Apsingekar V Deon P L | 2009 | IEEE Trans on Audio Speech and Language Proc2009，4，7： | 1 |
| 19 | Chips with everything: DNA microarrays in infectious diseases显示文摘 | Penelope A Bryant Deon Venter Roy Robins-Browne Nigel Curtis | 2004 | The Lancet Infectious Diseases2004，，： | 1 |
| 20 | Proteomic survey of the pathogenic Mycoplasma hyopneumoniae strain 7448 and identification of novel post-translationally modified and antigenic proteins显示文摘 | Paulo Marcos Pinto Gustavo Chemale Luiza Amaral de Castro Ana Paula Metz Costa Jalusa Deon Kich Marilene Henning Vainstein Arnaldo Zaha Henrique Bunselmeyer Ferreira | 2006 | Veterinary Microbiology2006，，1： | 1 |
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