|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection显示文摘Interleukin-17(IL-17),a member of the IL-17 cytokine family,plays a crucial role in mediating the immune response against extracellular bacteria and fungi in the lung.Although there is increasing evidence that IL-17 is involved in protective immunity against H1 and H3 influenza virus infections,little is known about the role of IL-17 in the highly pathogenic H5N1 influenza virus infection.In this study,we show that H5N1-infected IL-17 knockout(KO)mice exhibit markedly increased weight loss,more pronounced lung immunopathology and significantly reduced survival rates as compared with infected wild-type controls.Moreover,the frequency of B cells in the lung were substantially decreased in IL-17 KO mice after virus infection,which correlated with reduced CXCR5 expression in B cells and decreased CXCL13 production in the lung tissue of IL-17 KO mice.Consistent with this observation,B cells from IL-17 KO mice exhibited a significant reduction in chemokine-mediated migration in culture.Taken together,these findings demonstrate a critical role for IL-17 in mediating the recruitment of B cells to the site of pulmonary influenza virus infection in mice. | Xiaohui Wang Chris CS Chan Min Yang Jun Deng Vincent KM Poon Virtual HC Leung King-Hung Ko Jie Zhou Kwok Yung Yuen Bo-Jian Zheng Liwei Lu | 2011 | Cellular & Molecular Immunology2011，8，6： | 2 |
| 2 | Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction显示文摘 | Bivalacqua TJ Deng W Champion HC | 2004 | Methods Mol Biol2004，279，： | 1 |
| 3 | Establishment and char- acterization of a human first - trimester extravillous trophoblast cell line (TEV- 1 ) 显示文摘 | Feng HC Choy MY Deng W | 2005 | J Soc Gynecol Investig2005，12，4： | 1 |
| 4 | Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes 显示文摘 | DENG Y BI HC ZHAO LZ | 2008 | Drug Metab Lett2008，2，1： | 1 |
| 5 | The effects of sodiumferulate on early diabetic nephropathy显示文摘 | Zheng D Deng HC Zhao TF | 2001 | J Clin In-tern Med2001，18，6： | 1 |
| 6 | Suppression of mesangial cell proliferation and cxtracellular matrix production in streptozotocin- induced diabetic mice by adiponectin in vitro and in vivo 显示文摘 | Huang X Su YX Deng HC | 2014 | HormMetab Res2014，46，10： | 1 |
| 7 | Streptococcus mutans competencestimulating peptide inhibits Candida albicans hypha formation显示文摘 | Jarosz LM Deng DM vanderMei HC | 2009 | Eukaryot Cell2009，8，11： | 1 |
| 8 | Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in hu- man and rat primary hepatocytes显示文摘 | Deng Y Bi HC Zhao LZ | 2008 | Drug Metab Lett2008，2，1： | 1 |
| 9 | Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction显示文摘 | Bivalacqua TJ Deng W Champion HC | 2004 | Methods Mol Biol2004，279，： | 1 |
| 10 | Establishment and charac- terization of a human first - trimester extravillous trophoblast cell line (TEV- 1) 显示文摘 | Feng HC Choy MY Deng W | 2005 | J Soc Gynecol Investig2005，12，4： | 1 |
| 11 | Oxidative stress disrupts glucocorticoid hormone-dependent transcription of the amiloride-sensitive epithelial sodium channel alpha-subunit in lung epithelial cells through ERK-dependent and thioredoxin-sensitive pathways显示文摘 | Wang HC Zentner MD Deng HT | 2000 | J Biol Chem2000，275，： | 1 |
| 12 | Alteration of fatty acid components of erythrocyte membrane and insulin resistance in diabetic patients显示文摘 | Yang GY Li L Deng HC Qiu HX Wang SP Zhang SH | 1998 | Natl Med J China(中华医学杂志)1998，78，4： | 1 |
| 13 | Induction of eytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes 显示文摘 | Deng Y' Bi HC Zhao LZ | 2008 | Drug Metab Lett2008，2，1： | 1 |
| 14 | Microbial diversity in two cold spring on the Qing hai-Tibetan Plateau显示文摘 | Li GY Jiang HC Hou WG Wang shang Huang LQ Ren HL Deng SH Dong HL | | 0，，03： | 1 |
| 15 | Information processing in schizophrenia and bipolar disorder: A discriminant analysis 显示文摘 | Tam WCC Sewell KW Deng HC | 1998 | J Nerv Merit Di1998，186，： | 1 |
| 16 | Liver involvement in epidemic haemorrhagie fever, in situ hybridization, immunohistochemical and pathological studies 显示文摘 | SUN HC DENG PF WANG CJ | 1997 | J Gastroenterol Hepatol1997，12，7： | 1 |
| 17 | Modulation of ceramide- activated protein phosphatase 2A activity by low molecular weight aromatic compounds 显示文摘 | Leoni LM Shih HC Deng L | 1998 | Biochem Pharmacol1998，55，7： | 1 |
| 18 | Adiponectin inhibits PDGF-induced mesangial cell proliferation: regulation of mammalian target of rapamycin mediated survival pathway by adenosine 5-monophosphate activated protein kinase显示文摘 | SU YX DENG HC ZHANG MX | 2012 | Horm Metab Res2012，44，1： | 1 |
| 19 | Induction of cytochrome P450 3A by the ginkgo biloba extract and bilobalides in human and rat primary hepatocytes显示文摘 | Deng Y Bi HC Zhao LZ | 2008 | Drug Metabolism Letters2008，2，1： | 1 |
| 20 | Adiponectin inhibits PDGF-induced mesangial cell proliferation: regulation of mammalian target of rapamycimmediated survival pathway by adenosine 5-monophosphate-activated protein kinase显示文摘 | Su YX Deng HC Zhang MX | 2011 | Horm Metab Res2011，21，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员