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| 1 | Pembrolizumab-emerging treatment of pulmonary sarcomatoid carcinoma: A case report显示文摘BACKGROUND Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma(PSC),a rare,previously rapidly fatal subtype of nonsmall-cell lung cancer.CASE SUMMARY We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells.The patient was started on pembrolizumab and,after 5 cycles,there was a more than 80 percent decrease in the size of the tumor mass.Further decrease was seen at the end of 10 cycles.The patient has been tolerating pembrolizumab well,with no limiting side-effects.Fourteen months after first coming into the hospital,he remains asymptomatic.CONCLUSION Pembrolizumab appears as a viable emerging treatment for PSC. | Emanuela Cimpeanu Jibran Ahmed Wahib Zafar Adreana DeMarinis Svetoslav S Bardarov Shamim Salman Dennis Bloomfield | 2020 | World Journal of Clinical Cases2020，8，1： | 2 |
| 2 | Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research显示文摘 | Susan D. Richardson Michael J. Plewa Elizabeth D. Wagner Rita Schoeny David M. DeMarini | 2007 | Mutation Research-Reviews in Mutation Research2007，，1： | 2 |
| 3 | Survival update for the phase Ⅲ study of pemetrexed vs docetaxel in non-small cell lung cancer (NSCLC)显示文摘 | Demarinis F Paul S Hanna N | 2006 | J Clin Oncol2006，24，18： | 1 |
| 4 | Mutation spectra in salmonella of chlorinated, chloraminated, or ozonated drinking water extracts: comparison to MX 显示文摘 | DeMarini DM Abu-Shakra A Felton CF | 1995 | Environ Mol Mutagen1995，26，4： | 1 |
| 5 | Drowning in disinfection byproducts? Assessing swimming pool water 显示文摘 | Zwiener C Richardson S D DeMarini D M | 2008 | Environ Sci Technol2008，42，5： | 1 |
| 6 | Evidence forthe presence of mutagenic arylamines in human breast milk andDNA adducts in exfoliated breast ductal epithelial cells 显示文摘 | Thompson PA DeMarini DM Kadlubar FF | 2002 | En-viron Mol Mutagen2002，39，23： | 1 |
| 7 | Genotoxicity of tobacco smoke and tobacco smoke condensate: a review 显示文摘 | DeMarini D M | 2004 | Mutat Res2004，567，23： | 1 |
| 8 | Survival update for the phase Ⅲ study of pemetrexed vs docetaxel in non - small cell lung cancer (NSCLC) 显示文摘 | Demarinis F Paul S Hanna N etal | 2006 | Proc ASCO2006，7133，： | 1 |
| 9 | Research opportunities for cancer associated with indoor air pollution from solid-fuel combustion显示文摘 | Reid BC Ghazarian AA DeMarini DM | 2012 | Environ Health Perspect2012，120，11： | 1 |
| 10 | What's in the pool? a comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water显示文摘 | Richardson S D DeMarini D M Kogevinas M | 2010 | Environmental Health Perspectives2010，118，11： | 1 |
| 11 | Risph0sphonates:Prevention of bone metastases in lung cancer显示文摘 | Decoster L deMarinis F Syrigos K et a1 | 2012 | Rec Results Cancer Res2012，192，： | 1 |
| 12 | Survival update for the phase Ⅲ study of pemetrexed vs docetaxel in non - small cell lung cancer ( NSCLC ) 显示文摘 | Demarinis F Paul S Hanna N | 2006 | J Clin Oncol2006，，： | 1 |
| 13 | Do arsenosugars pose a risk to human health? The comparative toxieities of a trivalent and pentavalent arsenosugar 显示文摘 | Andrewes P Demarini D M Funasaka K | 2004 | Environ Sci Technol2004，38，： | 1 |
| 14 | PhaseⅢrandom-ized trial comparing three platinum-based doublets in advancednon small cell lung cancer显示文摘 | Scarliotti GV DeMarinis F RinaldiM | 2002 | J Clin Oncol2002，20，： | 1 |
| 15 | The septins:Roles in cytokinesis and other processes显示文摘 | DEMARINI D J VALENCIK M L | 1996 | Curr Opin Cell Biol1996，8，： | 1 |
| 16 | Estrogens, phytoestrogens and colorectal neoproliferative lesions显示文摘 | Michele Barone Sabina Tanzi Katia Lofano Maria Principia Scavo Raffaella Guido Lucia Demarinis Maria Beatrice Principi Antongiulio Bucci Alfredo Di Leo | 2008 | Genes & Nutrition2008，，1： | 1 |
| 17 | A randomised phase II trial of two sequential schedules of docetaxel and cisplatin followed by gemcitabine in patients with advanced non-small-cell lung cancer显示文摘 | Grossi F DeMarinis F Gebbia V | 2012 | Cancer Chemoth Pharrn2012，69，2： | 1 |
| 18 | Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae显示文摘 | Longtine M S McKenzie A Ⅲ Demarini D J | 1998 | Yeast1998，14，10： | 1 |
| 19 | Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research显示文摘 | Susan D. Richardson Michael J. Plewa Elizabeth D. Wagner Rita Schoeny David M. DeMarini | 2007 | Mutation Research-Reviews in Mutation Research2007，，1： | 1 |
| 20 | Dopamine receptor agonists显示文摘 | DeMarinis RM Hieble JP | 1998 | Drugs Future1998，14，8： | 1 |
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