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| 1 | Hepatitis C virus genotypes in Serbia and Montenegro: The prevalence and clinical signifi cance显示文摘AIM: To investigate the prevalence of hepatitis C virus (HCV) genotypes in Serbia and Montenegro and their in? uence on some clinical characteristics in patients with chronic HCV infection.METHODS: A total of 164 patients was investigated. Complete history, route of infection, assessment of al-cohol consumption, an abdominal ultrasound, standard biochemical tests and liver biopsy were done. Gene se-quencing of 5’ NTR type-specifi c PCR or commercial kits was performed for HCV genotyping and subtyping. The SPSS for Windows (version 10.0) was used for univariate regression analysis with further multivariate analysis. RESULTS: The genotypes 1, 2, 3, 4, 1b3a and 1b4 were present in 57.9%, 3.7%, 23.2%, 6.7%, 6.7% and 1.8% of the patients, respectively. The genotype 1 (mainly the subtype 1b) was found to be independent of age in sub-jects older than 40 years, high viral load, more severe necro-in? ammatory activity, advanced stage of fi brosis, and absence of intravenous drug abuse. The genotype 3a was associated with intravenous drug abuse and the age below 40. Multivariate analysis demonstrated age over 40 and intravenous drug abuse as the positive pre-dictive factors for the genotypes 1b and 3a, respectively. CONCLUSION: In Serbia and Montenegro, the geno-types 1b and 3a predominate in patients with chronic HCV infection. The subtype 1b is characteristic of older patients, while the genotype 3a is common in drug abus-ers. Association of the subtype 1b with advanced liverdisease, higher viral load and histological activity sug-gests earlier infection with this genotype and eventually its increased pathogenicity. | Neda Svirtlih Dragan Delic Jasmina Simonovic Djordje Jevtovic Ljubisa Dokic Eleonora Gvozdenovic Ivan Boricic Dragica Terzic Sladjana Pavic Gorana Neskovic Sonja Zerjav Vladimir Urban | 2007 | World Journal of Gastroenterology2007，13，3： | 5 |
| 2 | The influence of single and combined IL28B polymorphisms on response to treatment of chronic hepatitis C显示文摘 | Ivana Lazarevic Jelena Djordjevic Maja Cupic Danijela Karalic Dragan Delic Neda Svirtlih Jasmina Simonovic Petar Svorcan Natasa Milic Tanja Jovanovic | 2013 | Journal of Clinical Virology2013，，： | 2 |
| 3 | The role of sequestosome 1/p62 protein in amyotrophic lateral sclerosis and frontotemporal dementia pathogenesis显示文摘Amyotrophic lateral sclerosis and frontotemporal lobar degeneration are multifaceted diseases with genotypic,pathological and clinical overlap.One such overlap is the presence of SQSTM1/p62 mutations.While traditionally mutations manifesting in the ubiquitin-associated domain of p62 were associated with Paget’s disease of bone,mutations affecting all functional domains of p62 have now been identified in amyotrophic lateral sclerosis and frontotemporal lobar degeneration patients.p62 is a multifunctional protein that facilitates protein degradation through autophagy and the ubiquitin-proteasome system,and also regulates cell survival via the Nrf2 antioxidant response pathway,the nuclear factor-kappa B signaling pathway and apoptosis.Dysfunction in these signaling and protein degradation pathways have been observed in amyotrophic lateral sclerosis and frontotemporal lobar degeneration,and mutations that affect the role of p62 in these pathways may contribute to disease pathogenesis.In this review we discuss the role of p62 in these pathways,the effects of p62 mutations and the effect of mutations in the p62 modulator TANK-binding kinase 1,in relation to amyotrophic lateral sclerosis-frontotemporal lobar degeneration pathogenesis. | Adriana Delice Foster Sarah Lyn Rea | 2020 | Neural Regeneration Research2020，15，12： | 2 |
| 4 | A mixed integer goal program- ming model for discrete values of design requirements in QFD显示文摘 | DELICE E K GUNGOR Z | 2011 | International Journal of Production Research2011，49，29： | 1 |
| 5 | In vitro radiation-induced apoptosis and early response to low-dose radiotherapy in non- Hodgkins lymphomas显示文摘 | Dubray B Breton C Delic J | 1998 | Radiother Oncol1998，46，2： | 1 |
| 6 | A new mixed integer linear programming model for product development using quality function deployment 显示文摘 | Delice E K Gtingro Z | 2009 | Computer & Industrial Engineering2009，57，3： | 1 |
| 7 | New product design using FDMS and FANP under fuzzy environment显示文摘 | GO ¨ NG O ¨ R Z KILIC E DELICE | | 0，，11： | 1 |
| 8 | The role of lamivudine in the treatment of HBe antigen negative liver cirrhosis显示文摘 | Simonovic BJ Delic D Svirtlih N | 2006 | Med Pregl2006，59，9： | 1 |
| 9 | Eimeria papillata:up- regulation of specific miRNA-species in the mouse jejunum显示文摘 | Dkhil M Abdel-Baki AA Delic D | 2011 | Exp Parasitol2011，127，2： | 1 |
| 10 | Wireless sensor net- works for intrusion detection: packet traffic modeling 显示文摘 | Demirkol I Alagoz F Delic H | 2006 | IEEE Corn Letters2006，10，1： | 1 |
| 11 | The utility of PBPK in the safety assessment of chloroform and carbon tetrachloride显示文摘 | DELIC J I LILLY P D MACdONALD A J | 2000 | Regulatory Toxicology and Pharmacology2000，32，2： | 1 |
| 12 | Transmitter Diversity for Robustness to Channel Estimation Errors显示文摘 | Kurt T Delic H | 2005 | IEEE Letters2005，41，5： | 1 |
| 13 | Protein-carotenoid Concentrate from Lucerne Juice as the Source of Xanthophy and Protein for Layers 显示文摘 | Delic I | 2004 | Biotechnology Atocarstva2004，，10： | 1 |
| 14 | Doubly iterative equalization of continuous-phase modulation 显示文摘 | Ozgul B Koca M Delic H | 2007 | IEEE Trans on Communications2007，55，11： | 1 |
| 15 | Two-dimensional CRC for efficient transmission of ATM cells over CDMA 显示文摘 | Hocanin A Delic H and Sarin S V | 2000 | IEEE Communications Letters2000，4，4： | 1 |
| 16 | Maximum entropy aggregation of individual opinions显示文摘 | DELIC H | 1994 | IEEE Transactions on Systems Man and Cybernetics1994，24，4： | 1 |
| 17 | Investigation of ganciclovir resistance in CMV UL54 and UL97 gene regions in immunocompromised patients receiving gancyclovir treatment显示文摘 | Delice S G?kahmeto?lu S Kaynar L | 2015 | Mikrobiyol Bul2015，49，3： | 1 |
| 18 | Distrubution of HBV genotypes,subgenotypes and HBsAg subtypes among chronically infected patients in Serbia显示文摘 | Lazarevic I Cupic M Delic D | 2007 | Arch Virol2007，152，： | 1 |
| 19 | Two-dimensional CRC for efficient transmission of ATM cells over CDMA显示文摘 | Hocanin Aykut Delic Hakan Sarin Shanuj V | | 0，，04： | 1 |
| 20 | Histopathology of chronic hepatitis C in relation to virus genotype显示文摘 | Delic' D Nesic' Z Prostran M | 2006 | Vojnosanit Pregl2006，63，9： | 1 |
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