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2篇 您的检索式:作者名="David R Booth"
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1Interaction of IFNL3 with insulin resistance,steatosis and lipid metabolism in chronic hepatitis C virus infection显示文摘Metabolic changes are inextricably linked to chronic hepatitis C(CHC).Recently polymorphisms in the IFNL3(IL28B)region have been shown to be strongly associated with spontaneous and treatment induced recovery from hepatitis C virus(HCV)infection.Further,circumstantial evidence suggests a link between IFNL3single nucleotide polymorphisms and lipid metabolism,steatosis and insulin resistance in CHC.The emerging picture suggests that the responder genotypes of IFNL3polymorphisms are associated with a higher serum lipid profile,and less frequent steatosis and insulin resistance.This review analyzes the current data regarding this interaction and its meaning for HCV pathogenesis and disease progression.Mohammed Eslam David R Booth Jacob George Golo Ahlenstiel 2013World Journal of Gastroenterology2013,19,41:2
2Resistance to hepatitis C virus: potential genetic and immunological determinants显示文摘Michael M Mina Fabio Luciani Barbara Cameron Rowena A Bull Michael R Beard David Booth Andrew R Lloyd 2015The Lancet Infectious Diseases2015,,4:1
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