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| 1 | An eco-environmental friendly operation: An effective method to mitigate the harmful blooms in the tributary bays of Three Gorges Reservoir显示文摘Harmful algal blooms, which frequently occur in different tributaries, have become a serious water quality problem of the Three Gorges Reservoir (TGR) since its initial filling. A three-year monitoring campaign from 2008 to 2010 was conducted to identify the controlling factors of algal blooms and effective preventive measures. The following results were obtained: 1) Layered and bidirectional currents, called intrusive density currents, dominate the tributary bays of the TGR year round; 2) continuously increasing water level can make the intruding density current shift from the middle to the surface, and surface intrusive water can reduce the surface water temperature and break the stable stratification of the tributary; 3) the appearing or fading away of algal blooms is closely associated with fluctuations in the TGR water level. Thus, the water level fluctuation patterns of different 'tide-types' may prevent the occurrence of algal blooms in the spring and summer, and the 'stair-type' tides may control autumn blooms during the impounding period. These methods were feasible and effective throughout the actual TGR's operation in 2009 2011. These patterns formed an eco-environmentally friendly operation (EEFO) to mitigate algal blooms. As an in situ treatment with easier operation and less negative impact and loss, compared with chemical and filter-feeding fish methods, the EEFO is currently considered as the most feasible remedial measure to remit the eco-environmental problems at the Three Gorges Dam (TGD). | YANG ZhengJian LIU DeFu JI DaoBin XIAO ShangBin HUANG YuLing MA Jun | 2013 | Science China(Technological Sciences)2013，56，6： | 14 |
| 2 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5huquu90xk0kqb6q00.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 3 | Lithium insertion/desertion properties of LiFePO 4 cathode in a low temperature electrolyte modified with sodium chloride additive显示文摘 | Borong Wu Yonghuan Ren Daobin Mu Xiaojiang Liu Guchang Yang Zhe Sun | 2014 | Solid State Ionics2014，，： | 1 |
| 4 | Stable cycling of LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)/lithium metal batteries enabled by synergistic tuning the surface stability of cathode/anode显示文摘Ni-rich layered oxides(LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2))show great potential in long-range and low-cost lithiumion batteries.However,due to the high surface sensitivity,their practical application is hindered by interfacial instability with electrolytes under high voltage for long cyclic life.Herein,by combining both firstprinciple calculations and time-of-flight secondary ion mass spectrometry(TOF-SIMS),a novel surface fluorinated reconstruction(SFR)mechanism is proposed to improve the interfacial stability under high voltage,which could effectively regulate the surface fluoride species to desensitize the LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)interface.We demonstrate here that by tuning the ratio of fluoride species,the LiNi_(0.9)Co_(0.05)Mn_(0.05)O_(2)/Li battery could achieve excellent long-term and high voltage performance(163.5 mA h g^(-1)at 0.5 C for 300 cycles under 4.4 V),while the controlled sample decayed to 125.4 mA h g^(-1)after 300 cycles.Moreover,the favorable cross-talk effect induced by SFR further facilitates the incorporation of suitable amounts of Ni ions into the construction of stable solid electrolyte interface(SEI)layer for anode surface.Therefore,the ultra-long cycling stability under high voltage can be achieved by the robust cathode/electrolyte and Li/electrolyte interfaces,which results in excellent interfacial stability after long cycling.This work provides new insights into the surface design of cathode materials and improves the stability of the electrode-electrode interface under high voltage. | Chunli Li Xinyu Zhang Zhuolin Yang Haijian Lv Tinglu Song Shijie Lu Yuxiang Zhang Tianwen Yang Fan Xu Feng Wu Daobin Mu | 2023 | Journal of Energy Chemistry2023，，12： | 0 |
| 5 | Two star-shaped small molecule donors based on benzodithiophene unit for organic solar cells显示文摘Star-shaped small molecules have attracted great attention for organic solar cells(OSCs)because they have three-dimensional charge-transport characteristics,strong light absorption capacities and easily tunable energy levels.Herein,three-and four-armed star-shaped small molecule donors,namely BDT-3 Th and BDT-4 Th,respectively,have been successfully designed and synthesized,which used benzodithiophene(BDT)as the central unit.The two star-shaped intermediates(2 a and 2 b)could be simultaneously obtained by one-step of Suzuki coupling,and 1,2-dimethoxyethane played a key role in the Suzuki coupling.Both of them have excellent thermal stability,good solubility and broad absorption.Four-armed BDT-4 Th shows a slightly higher extinction coefficient,a deeper HOMO energy level and an obviously better phase separation morphology when blended with Y6 than three-armed BDT-3 Th.As a result,increased power conversion efficiency(PCE)of 5.83%is obtained in the BDT-4 Th:Y6-based OSC devices,which is obviously higher than that of the BDT-3 Th:Y6-based devices(PCE=3.78%).To the best of our knowledge,this is the highest PCE among the BDT-based star-shaped donors-based OSCs.This result provides an effective strategy to obtain star-shaped small molecule donor materials for high efficient organic solar cells. | Jun Xu Jinsheng Zhang Daobin Yang Kuibao Yu Dandan Li Zihao Xia Ziyi Ge | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 6 | An Open-Label Study of Pegylated Liposomal Doxorubicin,Vincristine, and Reduced-Dose Dexamethasone Combination Therapy in Newly Diagnosed Multiple Myeloma Patients in the Chinese Population显示文摘OBJECTIVE Though doxorubicin is highly activein the treatment of multiple myeloma, its toxicityprofile limits its therapeutic index. We performed thisstudy to evaluate the efficacy and safety of pegylatedliposomal doxorubicin (PLD, Caelyx^(?)), vincristine,and reduced-dose dexamethasone combinationtherapy in newly diagnosed multiple myeloma (MM)patients in a Chinese population.METHODS This was an open-label, single-armstudy in which newly diagnosed patients with MMreceived PLD 40 mg/m^2 intravenously on Day 1,vincristine 1.4 mg/m^2 intravenously (maximum 2 mg)on Day 1, and 40 mg of dexarnethasone (intravenouslyor orally) from Day 1 to Day 4. Treatment wasrepeated every 28 days for at least 4 cycles.RESULTS In the intent-to-treat (ITT) analysis, theoverall response rate was 68.29%, and the completeremission rate was 10.98%. The incidence of alladverse events was 46.34%. The most commonnon-hematologic toxicities were palmar-plantarerythrodysesthesia (13.4%) and stomatitis (6.1%).CONCLUSION PLD, vincristine, and a reduceddosedexamethasone combination (DVd) is aneffective and safe regimen in newly diagnosed MMpatients in a Chinese population. | Yang Shen Zhixiang Shen Bin Jiang Jian Hou Rong Zhan Lugui Qiu Daobin Zhou Jie Jin Juan Li Fanyi Meng Ping Zou Ting Liu Jianyong Li Chun Wang Depei Wu Jun Ma | 2009 | Clinical oncology and cancer resexreh2009，6，6： | 0 |
| 7 | Influence of asymmetric tidal mixing on sediment dynamics in a partially mixed estuary显示文摘To investigate the influence of asymmetric tidal mixing(ATM) on sediment dynamics in tidal estuaries, we developed a vertically one-dimensional idealized analytical model, in which the M_2 tidal flow, residual flow and suspended sediment concentration(SSC) are described. Model solutions are obtained in terms of tidallyaveraged, and tidally-varying components(M_2 and M_4) of both hydrodynamics and sediment dynamics. The effect of ATM was considered with a time-varying eddy viscosity and time-varying eddy diffusivity of SSC. For the first time, an analytical solution for SSC variation driven by varying diffusivity could be derived. The model was applied to York River Estuary, where higher(or lower) eddy diffusivity was observed during flood(or ebb) in a previous study. The model results agreed well with the observation in both hydrodynamics and sediment dynamics. The vertical sediment distribution under the influence of ATM was analyzed in terms of the phase lag of the M_2 component of SSC relative to tidal flow. The phase lag increases significantly in estuaries with typical ATM(higher diffusivity during flood and lower diffusivity during ebb) for the case of seaward-directed net bottom shear stress(e.g., strong river discharge). In contrary, the phase lag is reduced by ATM, if the tidally-averaged bottom shear stress is landward(e.g., strong horizontal density gradient). The dynamics of sediment transport was analyzed as a function of ATM phase lag to identify the time of highest sediment diffusivity, as well as a function of the residual flow, to evaluate the relative importance of seaward and landward residual flows. In estuaries with relative strong fresh water discharge or weak tidal forcing(in case of flood season or neap tide), the near bottom SSC could be higher during ebb than during flood, since the bottom shear stress is higher during ebb due to seaward residual flow. However, landward net sediment transport can be expected in these estuaries in case of a typical ATM, because higher diffusivity causes higher SSC and landward transport during the flood period, while both SSC and seaward transport could be lower during ebb. On the contrary, seaward sediment transport can be expected in estuaries with landward tidally mean bottom shear stress in case of a reverse ATM,where sediment diffusivity is higher during the ebb. | Zhongyong Yang Zhiming Liang Yufeng Ren Daobin Ji Hualong Luan Changwen Li Yujie Cui Andreas Lorke | 2023 | Acta Oceanologica Sinica2023，42，9： | 0 |
| 8 | Facile access to C-N bonds via unexpected side reactions of Knoevenagel condensation and their application in high-efficiency organic solar cells显示文摘The construction of C-N bonds is of great importance in the fields of biology,medicine,chemistry and materials science.Here,the replacement of organic base from pyridine to piperidine in the Knoevenagel condensation process unexpectedly yields a series of novel organic molecules containing C-N bonds.Interestingly,the synthesis method does not require any external transition-metals catalysis,and photo-/electro-catalysis.Additionally,when the new compound 1b is added as a third component to a well-known binary system of PM6:Y6,the efficiency of the organic solar cell is significantly improved,resulting in an outstanding efficiency of 18.0%,which is one of the highest values reported to date for PM6:Y6-based ternary organic solar cells. | Daobin Yang Shuncheng Yang Hongqian Wang Lin Xie Pengyu Yan Ziyi Ge | 2024 | Science China Chemistry2024，67，1： | 0 |
| 9 | Lithiated VO2(M)@Carbon Fibers Hybrid Host for Improving the Cycling Stability of Sulfur Cathode in Lithium-Sulfur Batteries显示文摘of main observation and conclusion We successfully prepared the Li-VO2(M)nanosheets via a facile lithiation method.After compositing with conductive carbon fibers,the sulfur host(Li-VO2(M)@CFs)combines the efficient adsorption ability of the VO2(M)with superior electronic conductivity of the carbon fibers.Besides,carbon fiber cloth used as the current collector can provide the 30 electronic channels.Therefore,the coin cells exhibited the superior reversible capacity of 1250 mA h g^-1 at 0.2 C and a low capacity decay value of 0.068%per cycle within 416 cycles at 1C,indicative of the favorable cycling stability.Moreover,even at a high rate of 5C,it also kept at a high discharge capacity of 401 mA h g^-1.In conclusion,this work discloses an attractive route to reduce the dissolution loss of lithium polysulfides(UPSs)and enhance the overall performance of Li-S batteries. | Yuxin Wang Ling Zhang Jiaying Bi Hao Yang Zhikun Zhao Daobin Mu Borong Wu | 2020 | Chinese Journal of Chemistry2020，38，12： | 0 |
| 10 | Complete blood and urine paraprotein tests as response assessments in multiple myeloma patients treated with bortezomib,cyclophosphamide,and dexamethasone显示文摘Background: This study assessed the effect of standardized efficacy markers on prognosis in patients with newly diagnosed multiple myeloma(MM)during the induction phase of treatment with bortezomib,cyclophosphamide,and dexamethasone(BCD).Methods :We retrospectively analyzed clinical data in 197 newly diagnosed MM patients treated with BCD as front-line regimen at Peking Union Medical College Hospital from January 1,2013 to December 31,2018.Results: There were 107 patients with International Staging System(ISS)III and 51 with paraprotein of light chain.Of these,77 completed nine cycles of the BCD regimen.As the number of treatment cycles increased,the proportions of serum and urine immunofixation electrophoresis(IFE)tests elevated from 40.39%to 62.22%and 16.75%to 37.78%,respectively.More than 90%of intact immunoglobulin chain MM patients were evaluated for blood M protein per cycle,but that of urinary M protein was less than 60%.The detection rate of urinary M protein in light chain MM was more than 70%per cycle.Patients with a very good partial response(VGPR)had longer progression-free survival(PFS)than those with uncertain VGPR(32 vs.26 months,p=0.0336).Of the 141 patients who completed at least four cycles without undergoing autologous hematopoietic stem cell transplantation,those who were regularly assessed at every other cycle showed more favorable PFS than those who visited irregularly(27 vs.22 months,p=0.059).Conclusion: Urinary M protein detection rate is significantly lower than that in serum,leading to an overestimation of efficacy,premature reduction of treatment intensity,and shortened PFS.Precise response assessments are critical to treatment decisions and clinical diagnoses. | Xialu Lan Fujing Zhang Chen Yang Wei Su Jianhua Du Shuangjiao Liu Miao Chen Bing Han Daobin Zhou Junling Zhuang | 2024 | Chronic Diseases and Translational Medicine2024，10，1： | 0 |
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