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| 1 | uorescence microendoscopy imaging based on GRIN lenses with one- and two-photon excitation modes显示文摘 | Wei YAN Xiao PENG Danying LIN Qi WANG Jian GAO Teng LUO Jie ZHOU Tong YE Junle QU Hanben NIU | 2015 | Frontiers of Optoelectronics2015，8，2： | 2 |
| 2 | Physiological and genetic properties of tomato fruits from 2 cultivars differing in chilling tolerance at cold storage显示文摘 | ZHAO Danying SHEN Lin FAN Bei | 2009 | J Food Sci2009，74，5： | 1 |
| 3 | Ethylene and cold partici- pate in the regulation ofLeCBF1 gene expression in postharvest tomato fruits显示文摘 | ZHAO Danying SHEN Lin FAN Bei | 2009 | FEBS Lett2009，583，20： | 1 |
| 4 | Ethylene and cold participate in the regulation of LeCBF1 gene expression in postharvest tomato fruits显示文摘 | Danying Zhao Lin Shen Bei Fan Mengmeng Yu Yang Zheng Shengnan Lv Jiping Sheng | 2009 | FEBS Letters2009，，20： | 1 |
| 5 | COVID-19 reinfection in the presence of neutralizing antibodies显示文摘Due to the high transmissibility of the SARS-CoV-2 virus,it continues to infect over 300000 people worldwide per day(WHO statistics,December 2020),even almost one year after the first COVID-19 cases were confirmed[1,2].One of the most important public health discussions being undertaken currently concerns the protective nature of the immune response and the possibility of reinfection in recovered individuals. | Ju Zhang Nan Ding Lili Ren Rui Song Danying Chen Xuesen Zhao Budong Chen Junyan Han Jiarui Li Yangzi Song Lin Di Kai Han Fengting Yu Ruming Xie Zhihai Chen Wen Xie Jingyuan Liu Shan Cen Yuhai Bi Angela R.Wu Fujie Zhang Chen Chen Hui Zeng | 2021 | National Science Review2021，8，4： | 1 |
| 6 | Nitric oxide synthase as a postharvest response in pathogen resistance of tomato fruit显示文摘 | Yang Zheng Lin Shen Mengmeng Yu Bei Fan Danying Zhao Lingyi Liu Jiping Sheng | 2010 | Postharvest Biology and Technology2010，，1： | 1 |
| 7 | Enhancing tylosin production by combinatorial overexpression of efflux,SAM biosynthesis,and regulatory genes in hyperproducing Streptomyces xinghaiensis strain显示文摘Tylosin is a 16-membered macrolide antibiotic widely used in veterinary medicine to control infections caused by Gram-positive pathogens and mycoplasmas.To improve the fermentation titer of tylosin in the hyperproducing Streptomyces xinghaiensis strain TL01,we sequenced its whole genome and identified the biosynthetic gene cluster therein.Overexpression of the tylosin efflux gene tlrC,the cluster-situated S-adenosyl methionine(SAM)synthetase gene metK_(cs),the SAM biosynthetic genes adoK_(cs)-metFcs,or the pathway-specific activator gene tylR enhanced tylosin production by 18%,12%,11%,and 11%in the respective engineered strains TLPH08-2,TLPH09,TLPH10,and TLPH12.Co-overexpression of metK_(cs)and adoK_(cs)-metFcs as two transcripts increased tylosin production by 22%in the resultant strain TLPH11 compared to that in TL01.Furthermore,combinational overexpression of tlrC,metK_(cs),adoK_(cs)-metFcs,and tylR as four transcripts increased tylosin production by 23%(10.93g/L)in the resultant strain TLPH17 compared to that in TL01.However,a negligible additive effect was displayed upon combinational overexpression in TLPH17 as suggested by the limited increment of fermentation titer compared to that in TLPH08-2.Transcription analyses indicated that the expression of tlrC and three SAM biosynthetic genes in TLPH17 was considerably lower than that of TLPH08-2 and TLPH11.Based on this observation,the five genes were rearranged into one or two operons to coordinate their overexpression,yielding two engineered strains TLPH23 and TLPH24,and leading to further enhancement of tylosin production over TLPH17.In particular,the production of TLPH23 reached 11.35 g/L.These findings indicated that the combinatorial strategy is a promising approach for enhancing tylosin production in high-yielding industrial strains. | Penghui Dai Yuyao Qin Luyuan Li Haidi Li Lihuo Lv Danying Xu Yuqing Song Tingting Huang Shuangjun Lin Zixin Deng Meifeng Tao | 2023 | Synthetic and Systems Biotechnology2023，8，3： | 0 |
| 8 | Fast fluorescence lifetime imaging techniques:A review on challenge and development显示文摘Fluorescence lifetime imaging microscopy(FLIM)is increasingly used in biomedicine,material science,chemistry,and other related research fields,because of its advantages of high specificity and sensitivity in monitoring cellular microenvironments,studying interaction between proteins,metabolic state,screening drugs and analyzing their efficacy,characterizing novel materials,and diagnosing early cancers.Understandably,there is a large interest in obtaining FLIM data within an acquisition time as short as possible.Consequently,there is currently a technology that advances towards faster and faster FLIM recording.However,the maximum speed of a recording technique is only part of the problerm.The acquisition time of a FLIM image is a complex function of many factors.These include the photon rate that can be obtained from the sample,the amount of information a technique extracts from the decay functions,the fficiency at which it determines fluorescence decay parameters from the recorded photons,the demands for the accuracy of these parameters,the number of pixels,and the lateral and axial resolutions that are obtained in biological materials.Starting from a discussion of the parameters which determine the acquisition time,this review will describe existing and emerging FLIM techniques and data analysis algo-rithms,and analyze their performance and recording speed in biological and biomedical applications. | Xiongbo Liu Danying Lin Wolfgang Becker Jingjing Niu Bin Yu Liwei Liu Junle Qu | 2019 | Journal of Innovative Optical Health Sciences2019，，5： | 0 |
| 9 | Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity显示文摘Dear Editor,The coronavirus disease 2019(COVID-19)pandemic is generating a demand for simultaneous vaccine development,which is expected to prevent future outbreaks by eliciting sufficient and protective immunity. | Junyan Han Ning Zhang Danying Chen Yuhuan Gong Guoli Li Yaxian Kong Lin Pu Chen Chen Jingyuan Liu Qi Wang Ju Zhang Xuesen Zhao Juan Du Kai Han Chuan Song Linghang Wang Mingxi Hua Yu Hao Rui Song Yangzi Song Fengting Yu Siyuan Yang Haofeng Xiong Wei Zhang George F.Gao Fujie Zhang Ang Li Hui Zeng Yuhai Bi | 2022 | Science China(Life Sciences)2022，65，1： | 0 |
| 10 | Weakly supervised 2D human pose transfer显示文摘We present a novel method for pose transfer between two 2 D human skeletons. When the bone lengths and proportions between the two skeletons are significantly different, pose transfer becomes a challenging task, which cannot be accomplished by simply copying the joint positions or the bone directions.Our data-driven approach utilizes a deep neural network trained, in a weakly supervised fashion, to encode a skeleton into two separate latent codes, one representing its pose, and another representing the skeleton’s proportions(skeleton-ID). The network is given two skeletons, and learns to combine the pose of one with the skeleton-ID of the other. Lacking supervision on the poses, we develop a novel loss that qualitatively compares poses of different skeletons. We evaluate the performance of our method on a large set of poses.The advantages of avoiding supervision are demonstrated by showing transfer of extreme poses, as well as between uncommon skeleton proportions. | Qian ZHENG Yajie LIU Zhizhao LIN Dani LISCHINSKI Daniel COHEN-OR Hui HUANG | 2021 | Science China(Information Sciences)2021，64，11： | 0 |
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