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| 1 | Sausage: protein threading with flexible force fields显示文摘 | Thomas Huber Anthony J Russell Daniel Ayers | 1999 | Bioinformatics1999，15，12： | 1 |
| 2 | Sausage: protein threading with flexible force fields 显示文摘 | Thomas Huber Anthony J Russell Daniel Ayers | 1999 | Bioinformaties1999，15，： | 1 |
| 3 | Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma显示文摘 | Hitoshi Yoshiji Shigeki Kuriyama Junichi Yoshii Yasuhide Ikenaka Ryuichi Noguchi Daniel J. Hicklin James Huber Toshiya Nakatani Hirohisa Tsujinoue Koji Yanase Hiroo Imazu Hiroshi Fukui | 2002 | Hepatology2002，，4： | 1 |
| 4 | Impaired in vitro lymphocyte responses in patients with elevated pentacholorophenol blood levels显示文摘 | Daniel V Huber W Bauer K | 1995 | Archives of Environmental Health1995，50，4： | 1 |
| 5 | Clinical impact of programmed cell death ligand 1 expression in colorectal cancer显示文摘 | Raoul A. Droeser Christian Hirt Carsten T. Viehl Daniel M. Frey Christian Nebiker Xaver Huber Inti Zlobec Serenella Eppenberger-Castori Alexander Tzankov Raffaele Rosso Markus Zuber Manuele Giuseppe Muraro Francesca Amicarella Eleonora Cremonesi Michael H | 2013 | European Journal of Cancer2013，，9： | 1 |
| 6 | Association of elevated blood levels of pentachlomphenol (PCP) with cellular and humoral immunodeficiencies 显示文摘 | DANIEL V HUBER W BAUER K | 2001 | Arch Environ Health2001，56，1： | 1 |
| 7 | Immunode sign of experimental sepsis by cecal ligation and puneture显示文摘 | Daniel Rittirseh Markus S Huber -Lang Michael A Flied | 2009 | Nature Protocols2009，4，： | 1 |
| 8 | Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration显示文摘 | C. Bettina Portmann-Lanz Andreina Schoeberlein Alexander Huber Ruth Sager Antoine Malek Wolfgang Holzgreve Daniel V. Surbek | 2006 | American Journal of Obstetrics and Gynecology2006，，3： | 1 |
| 9 | Neoadjuvant radiochemotherapy for locally advanced gastric cancer: Long-term results of a phase I trial显示文摘 | Abdelkarim S. Allal Daniel Zwahlen Marie-Anne Bründler Raymond de Peyer Philippe Morel Olivier Huber Arnaud D. Roth | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，5： | 1 |
| 10 | The market timing skills of hedge funds during the financial crisis显示文摘 | Arnaut Cave Georges Huber Danielle Soigne | 2011 | Managerial Finance2011，38，1： | 1 |
| 11 | Fully Automatic Registration of Multiple 3D Data Sets 显示文摘 | Daniel F Huber Martial Hebert | 2003 | Image and Vision Computing2003，21，： | 1 |
| 12 | Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration显示文摘 | C. Bettina Portmann-Lanz Andreina Schoeberlein Alexander Huber Ruth Sager Antoine Malek Wolfgang Holzgreve Daniel V. Surbek | 2006 | American Journal of Obstetrics and Gynecology2006，，3： | 1 |
| 13 | Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion?Findings from the NCAA and Department of Defense CARE Consortium显示文摘Background:Current protein biomarkers are only moderately predictive at identifying individuals with mild traumatic brain injury or concussion.Therefore,more accurate diagnostic markers are needed for sport-related concussion.Methods:This was a multicenter,prospective,case-control study of athletes who provided blood samples and were diagnosed with a concussion or were a matched non-concussed control within the National Collegiate Athletic Association-Department of Defense Concussion Assessment,Research,and Education Consortium conducted between 2015 and 2019.The blood was collected within 48 h of injury to identify protein abnormalities at the acute and subacute timepoints.Athletes with concussion were divided into 6 h post-injury(0-6 h post-injury)and after 6 h postinjury(7-48 h post-injury)groups.We applied a highly multiplexed proteomic technique that used a DNA aptamers assay to target 1305proteins in plasma samples from athletes with and without sport-related concussion.Results:A total of 140 athletes with concussion(79.3%males;aged 18.71±1.10 years,mean±SD)and 21 non-concussed athletes(76.2%males;19.14±1.10 years)were included in this study.We identified 338 plasma proteins that significantly differed in abundance(319 upregulated and 19 downregulated)in concussed athletes compared to non-concussed athletes.The top 20 most differentially abundant proteins discriminated concussed athletes from non-concussed athletes with an area under the curve(AUC)of 0.954(95%confidence interval:0.922-0.986).Specifically,after 6 h of injury,the individual AUC of plasma erythrocyte membrane protein band 4.1(EPB41)and alpha-synuclein(SNCA)were 0.956 and 0.875,respectively.The combination of EPB41 and SNCA provided the best AUC(1.000),which suggests this combination of candidate plasma biomarkers is the best for diagnosing concussion in athletes after 6 h of injury.Conclusion:Our data suggest that proteomic profiling may provide novel diagnostic protein markers and that a combination of EPB41 and SNCA is the most predictive biomarker of concussion after 6 h of injury. | Rany Vorn Christina Devoto Timothy B.Meier Chen Lai Sijung Yun Steven P.Broglio Sara Mithani Thomas W.McAllister Christopher C.Giza Hyung-Suk Kim Daniel Huber Jaroslaw Harezlak Kenneth L.Cameron Gerald McGinty Jonathan Jackson Kevin M.Guskiewicz Jason P.Mihalik Alison Brooks Stefan Duma Steven Rowson Lindsay D.Nelson Paul Pasquina Michael A.McCrea Jessica M.Gill the CARE Consortium Investigators | 2023 | Journal of Sport and Health Science2023，12，3： | 0 |
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