维普中文期刊产品整合服务
12篇 您的检索式:作者名="Daniel Ebner"
    题名 作者 年代 出处 被引量
1Application of high gradient magnetic separation principles to magnetic drug targeting显示文摘Ritter James A Ebner Armin D Daniel Karen D 2004Journal of Magnetism and Magnetic Materials2004,280,2:1
2Application of high gradient magnetic separation principles to magnetic drugtargeting 显示文摘Ritter James A Ebner Amain D Daniel Karen D 2004Journal of Magnetism and Magnetic Materials2004,280,2:1
3Application of high gradient magnetic separation principles to magnetic drug targeting显示文摘RITTER J A EBNER A D DANIEL K D 2004Journal of Magnetism and Magnetic Materials2004,280,9:1
4Application of high gradient magnetic separation principles to magnetic drug targeting 显示文摘James A Ritter Armin D Ebner Karen D Daniel 2004J Mag Mag Mat2004,280,23:1
5Carbon blacks for lead-acid batteries in micro-hybrid applications – Studied by transmission electron microscopy and Raman spectroscopy显示文摘Ellen Ebner Daniel Burow Jana Panke Alexander B?rger Armin Feldhoff Paolina Atanassova Jesus Valenciano Michael Wark Eckart Rühl 2013Journal of Power Sources2013,,:1
6Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer显示文摘Objective: Patients with BRAF-mutant colorectal cancer(CRC) have a poor prognosis. Molecular status is not currently used to select which drug to use in combination with radiotherapy. Our aim was to identify drugs that radiosensitise CRC cells with known BRAF status.Methods: We screened 298 oncological drugs with and without ionising radiation in colorectal cancer cells isogenic for BRAF. Hits from rank product analysis were validated in a 16-cell line panel of human CRC cell lines, using clonogenic survival assays and xenograft models in vivo.Results: Most consistently identified hits were drugs targeting cell growth/proliferation or DNA damage repair. The most effective class of drugs that radiosensitised wild-type and mutant cell lines was PARP inhibitors. In clonogenic survival assays, talazoparib produced a radiation enhancement ratio of 1.9 in DLD1(BRAF-wildtype) cells and 1.8 in RKO(BRAF V600 E) cells. In DLD1 xenografts, talazoparib significantly increased the inhibitory effect of radiation on tumour growth(P ≤ 0.01).Conclusions: Our method for screening large drug libraries for radiosensitisation has identified PARP inhibitors as promising radiosensitisers of colorectal cancer cells with wild-type and mutant BRAF backgrounds.Rebecca Carter Azadeh Cheraghchi-Bashi Adam Westhorpe Sheng Yu Yasmin Shanneik Elena Seraia Djamila Ouaret Yasuhiro Inoue Catherine Koch Jenny Wilding Daniel Ebner Anderson J. Ryan Francesca M. Buffa Ricky A. Sharma 2019Cancer Biology & Medicine2019,16,2:1
7显示文摘Ritter J A Ebner A D Daniel K D 2004J Magn Magn Mater2004,280,23:1
8How to Rescue CRM 显示文摘Ebner Manuel Arthur Levitt Daniel 2002McKinsey Quarterly2002,,:1
9Application of high gradient magnetic separation principles to magnetic drug targeting显示文摘 Ebner A D Daniel K D 2004J Mag Mag Mat2004,,280:1
10Carbon blacks for lead-acid batteries in micro-hybrid applica- tions -- Studied by transmission electron microscopy and Raman spe ctroscopy 显示文摘Ebner Ellen Burow Daniel Panke Jana 2013Journal of Power Sources2013,222,:1
11Carbon blacks for the extension of the cycle life in flooded lead acid batteries for micro-hybrid applications显示文摘Ellen Ebner Daniel Burow Alexander B?rger Michael Wark Paolina Atanassova Jesús Valenciano 2013Journal of Power Sources2013,,:1
12How to Rescue CRM显示文摘EBNER MANUEL HU ARTHUR LEVITT DANIEL MCCRORY JIM 2002The McKinsey Quarterly2002,10,3:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费