维普中文期刊产品整合服务
142篇 您的检索式:作者名="Panke"
    题名 作者 年代 出处 被引量
1Aqueous Self-Assembly of Block Copolymers to Form Manganese Oxide-Based Polymeric Vesicles for Tumor Microenvironment-Activated Drug Delivery显示文摘Molecular self-assembly is crucially fundamental to nature.However,the aqueous self-assembly of polymers is still a challenge.To achieve self-assembly of block copolymers [(polyacrylic acid-block-polyethylene glycol-block-polyacrylic acid(PAA68-b-PEG86-b-PAA68)] in an aqueous phase,manganese oxide(MnO2) is first generated to drive phase separation of the PAA block to form the PAA68-b-PEG68-b-PAA68/MnO2 polymeric assembly that exhibits a stable structure in a physiological medium.The polymeric assembly exhibits vesicular morphology with a diameter of approximately 30 nm and high doxorubicin(DOX) loading capacity of approximately 94%.The transformation from MnO2 to Mn2+caused by endogenous glutathione(GSH)facilitates the disassembly of PAA68-b-PEG68-b-PAA68/MnO2 to enable its drug delivery at the tumor sites.The toxicity of DOXloaded PAA68-b-PEG68-b-PAA69/MnO2 to tumor cells has been verified in vitro and in vivo.Notably,drug-loaded polymeric vesicles have been demonstrated,especially in in vivo studies,to overcome the cardiotoxicity of DOX.We expect this work to encourage the potential application of polymer self-assembly.Yalei Miao Yudian Qiu Mengna Zhang Ke Yan Panke Zhang Siyu Lu Zhongyi Liu Xiaojing Shi Xubo Zhao 2020Nano-Micro Letters2020,12,9:2
2Degree Reduction of B6zier Curves and It's Error Analysis显示文摘Pank YB Chui UJ 1997Austral Soc Ser B1997,36,:1
3Kinematics and dynamics models of hybrid robot manipulator for propeller grinding 显示文摘Min Ki Lee Kun Woo pank 1999Journal of Robotic Systems1999,16,3:1
4Management of constipation in residents with dementia:sorbitol effectiveness and cost显示文摘Volicer L Lane P Panke J 2005J Am Med Dir Assoc2005,6,3:1
5Neurophysiologic monitoring to assure delivery of retrograde cerebral perfusion 显示文摘 Edmonds HL Pank JR 1997J Thorac Cardiovasc Surg1997,113,:1
6Trends and innovations in industrial biocatalysis for the production of fine chemicals 显示文摘Panke S Held M Wubbolts M 2004Curt Opin Biotechnol2004,15,:1
7Carbon blacks for lead-acid batteries in micro-hybrid applications-Studied by transmission electron microscopy and Raman spectroscopy显示文摘Ebner E Burow D Panke J 2013Journal of Power Sources2013,222,0:1
8The production of fine chemicals by biotrans -formations 显示文摘Straathof A J J Panke S Schmid A 2002Curt Opin Biotechnol2002,13,:1
9A bound of generalized competition index of a primitive digraph 显示文摘Kim H K Pank S G 2012Linear Algebra and its Applications2012,436,1:1
10Simultaneous induction of neuropeptide Y and gonadotrophin releasing hormone release in the rabbit hypotlhalamus显示文摘PANK Y F KHORRAM O KYANARD A H 1986Neuroendocrinol1986,49,:1
11Analysis of Pseudomonas putida alkane degradation gene clusters and flanking insertion sequences:evolution and regulation of the alk genes 显示文摘VAN BEILEN J B PANKE S LUCCHINI S 2001Microbiology2001,147,:1
12Effect of IL-1 and IL- 6 oxytocin secretion in human uterine smooth muscle cell 显示文摘Friebe HU Chiao TP Pank PN 2001Am J of Reprod Immunol2001,46,3:1
13Normal-incidenceintersubband ( In, Ga) As/GaAs quantum dot infraredphotodetectors显示文摘PANK D TOWL E KENNERLY S 1998Applied Physics Letter1998,,14:1
14Systematic assignment of thermodynamic constraints in metabolic network models 显示文摘Kummel A Panke S Heinemann M 2006BMC Bioinformatics2006,7,:1
15The production of fine chemicals by biotransformations显示文摘Straathof A J J Panke S Schmid A 2002Current Opinion in Biotechnology2002,13,6:1
16Endoscope-assisted microsurgery for microvascular compression syndromes 显示文摘Pank R Sckhar LN Stimac D 2004Neurosurgery2004,54,4:1
17Reduction in resource Utilization bgan asthma outroach program 显示文摘 Loane KG Panks P 1995Archp-cdiatr Adiaetr Adolesc Med1995,149,4:1
18Technical Project Guide-Marine Application 显示文摘Gerhard Gotz Carsten Panke Karl Steinbeck 2004MTU2004,,:1
19Effect of increasing serum albumin on serum lipoptotein concentrateion in patients receiving CAPD显示文摘Yang WS Min WK Pank JS 2002Am J Kidney Dis2002,30,4:1
20A practical approach of continuous processing to high energetic nitration reactions in microreacotrs 显示文摘Panke G Schwalbe T Stirner W 2003Synthesis2003,18,:1
返回顶部 每页显示:
共8页 首页 上一页 第1页 下一页 末页 /8 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费